Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Kevin Murray Schaab"'
Autor:
Kevin Murray Schaab, Jane H Bentley, Jilly F. Evans, Virginia Norris, Christopher D. King, Jeroen van de Wetering de Rooij, John H. Hutchinson, Masanori Yamada, Gretchen Bain, Melissa Rewolinski, Jasmine Eleanor Zunic, Nicholas Simon Stock, Claire Ambery, Angelina M. Santini
Publikováno v:
British Journal of Clinical Pharmacology. 75:779-790
Aim To assess the pharmacokinetics, pharmacodynamics, safety and tolerability of the 5-lipoxygenase-activating protein inhibitor, GSK2190915, after oral dosing in two independent phase I studies, one in Western European and one in Japanese subjects,
Autor:
Janice Darlington, Daniel S. Lorrain, Christopher Baccei, Charles Chapman, Hutchinson John H, Christopher D. King, Catherine Lee, Lucia Correa, Gretchen Bain, Pat Prodanovich, Peppi Prasit, Kevin Murray Schaab, Nicholas Simon Stock, Angelina M. Santini, Jilly F. Evans
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(15)
AM643 (compound 6, 3-{3-tert-butylsulfanyl-1-[4-(5-methoxy-pyrimidin-2-yl)-benzyl]-5-(5-methyl-pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid) was identified as a potential candidate for formulation as a topical agent for the treatme