Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Kevin Miyashiro"'
Autor:
Hyun-Bum Kim, Jacqueline Morris, Kevin Miyashiro, Tõnis Lehto, Ülo Langel, James Eberwine, Jai-Yoon Sul
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102436- (2021)
Summary: Ethanol (EtOH) abuse induces significant mortality and morbidity worldwide because of detrimental effects on brain function. Defining the contribution of astrocytes to this malfunction is imperative to understanding the overall EtOH effects
Externí odkaz:
https://doaj.org/article/8a873a83823d4e4a9e1672810a900d9d
Autor:
Hyun-Bum, Kim, Jacqueline, Morris, Kevin, Miyashiro, Tõnis, Lehto, Ülo, Langel, James, Eberwine, Jai-Yoon, Sul
Publikováno v:
iScience. 24(5)
Ethanol (EtOH) abuse induces significant mortality and morbidity worldwide because of detrimental effects on brain function. Defining the contribution of astrocytes to this malfunction is imperative to understanding the overall EtOH effects due to th
Autor:
James Eberwine, Jai-Yoon Sul, Jacqueline Morris, Ülo Langel, Kevin Miyashiro, Tõnis Lehto, Hyun Bum Kim
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102436-(2021)
Summary Ethanol (EtOH) abuse induces significant mortality and morbidity worldwide because of detrimental effects on brain function. Defining the contribution of astrocytes to this malfunction is imperative to understanding the overall EtOH effects d
Autor:
Peter A. Buckley, Ditte Lovatt, Jennifer M. Spaethling, Terri Schochet, Chantal Francis, James Eberwine, Junhyong Kim, Jacqueline Morris, Tae Kyung Kim, Jai-Yoon Sul, Jaehee Lee, Tiina Peritz, Kevin Miyashiro, Miler T. Lee, Hannah Dueck
Publikováno v:
Journal of the Royal Society Interface
The building blocks of complex biological systems are single cells. Fundamental insights gained from single-cell analysis promise to provide the framework for understanding normal biological systems development as well as the limits on systems/cellul
Autor:
Stephen A. Fisher, Jai-Yoon Sul, James Eberwine, Peter T. Buckley, Thomas J. Bell, Kevin Miyashiro, Miler T. Lee, Junhyong Kim
Publikováno v:
Neuron. 69:877-884
RNA precursors give rise to mRNA after splicing of intronic sequences traditionally thought to occur in the nucleus. Here, we show that intron sequences are retained in a number of dendritically-targeted mRNAs, using microarray and Illumina sequencin
Autor:
James Eberwine, Kevin Miyashiro
Publikováno v:
Cold Spring Harbor protocols. 2015(5)
The interactions between various RNA-binding proteins (RBPs) and the RNA transcripts they bind strongly influence posttranscriptional control of gene expression in vertebrates. The hundreds of vertebrate RBPs that have been identified within the geno
Autor:
Theresa J Kannanayakal, Emelía Eiríksdóttir, James Eberwine, Ülo Langel, Jennifer Zielinski, Kalle Kilk, Jeanine Jochems, Tiina Peritz, Kevin Miyashiro
Publikováno v:
Proceedings of the National Academy of Sciences. 103:1557-1562
To understand the role of RNA-binding proteins (RBPs) in the regulation of gene expression, methods are needed for the in vivo identification of RNA-protein interactions. We have developed the peptide nucleic acid (PNA)-assisted identification of RBP
Autor:
B. Belt, Jai-Yoon Sul, Philip G. Haydon, Kevin Miyashiro, Jason Glanzer, James Eberwine, Lindy E. Barrett
Publikováno v:
Proceedings of the National Academy of Sciences. 102:16859-16864
Dendrites are specialized extensions of the neuronal soma that contain components of the cellular machinery involved in RNA and protein metabolism. Several dendritically localized proteins are associated with the precursor-mRNA (pre-mRNA) splicing co
Autor:
David A. Hinkle, Tiina Pajunen, Kevin Miyashiro, Arezou Sarabi, James Eberwine, Jennifer Zielinski, Tracy K. McIntosh, Jason Glanzer, Brian Belt
Publikováno v:
Progress in Neurobiology. 72:129-142
The cellular and the inter-connective complexity of the central nervous system (CNS) necessitate's analysis of functioning at both the system and single cell levels. Systems neuroscience has developed procedures that facilitate the analysis of multic
Autor:
James Eberwine, Kevin G. Becker, Ivan Jeanne Weiler, Salvatore Carbonetto, Lei Liu, T.Patrick Purk, Tanya Barret, William T. Greenough, Kevin Miyashiro, Andrea Beckel-Mitchener
Publikováno v:
Neuron. 37(3):417-431
The Fragile X mental retardation-1 (Fmr1) gene encodes a multifunctional protein, FMRP, with intrinsic RNA binding activity. We have developed an approach, antibody-positioned RNA amplification (APRA), to identify the RNA cargoes associated with the