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Publikováno v:
Toxicologic Pathology. 49:334-348
Afrezza delivers inhaled insulin using the Gen2 inhaler for the treatment of patients with type 1 and type 2 Diabetes. Afrezza was evaluated in long-term nonclinical pulmonary safety studies in 2 toxicology species. Chronic inhalation toxicology stud
Autor:
Dolorès Carballo, Sherwin Silo, Patricia Stotland, Myriam Triest, Kevin McInally, Patrick Normand, Frederick E. Reno, Claude A. Piché
Publikováno v:
BMC Pharmacology & Toxicology
Background Glucagon nasal powder (GNP), a novel intranasal formulation of glucagon being developed to treat insulin-induced severe hypoglycemia, contains synthetic glucagon (10 % w/w), beta-cyclodextrin, and dodecylphosphocholine. The safety of this