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For millennia, “the North” has held a powerful sway in Western culture. Long seen through contradictions—empty of life yet full of promise, populated by indigenous communities yet ripe for conquest, pristine yet marked by a long human history�

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Toward Artificial Immunotoxins: Traceless Reversible Conjugation of RNase A with Receptor Targeting and Endosomal Escape Domains

Autor: Xiaowen Liu, Ulrich Lächelt, Wolfgang Rödl, Ernst Wagner, Kevin Maier, Peng Zhang

Publikováno v: Molecular pharmaceutics. 14(5)

The specific transport of bioactive proteins into designated target cells is an interesting and challenging perspective for the generation of innovative biopharmaceuticals. Natural protein cytotoxins perform this task with outstanding efficacy. They

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd823106dcfb740ae4902d242890e68d
https://pubmed.ncbi.nlm.nih.gov/28457141

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Sequence Defined Disulfide-Linked Shuttle for Strongly Enhanced Intracellular Protein Delivery

Autor: Kevin Maier, Ernst Wagner, Irene Martin

Publikováno v: Molecular Pharmaceutics. 9:3560-3568

Intracellular protein transduction technology is opening the door for a promising alternative to gene therapy. Techniques have to address all critical steps, like efficient cell uptake, endolysosomal escape, low toxicity, while maintaining full funct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f0c716a846dac5ff5e4fb141f77369
https://doi.org/10.1021/mp300404d

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