Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Kevin Macon"'
Autor:
Limbo Liu, John C. Kappes, Peter A. Sloane, Liping Tang, Marina Mazur, Carmel M. McNicholas, Kevin Macon, Lawrence J. DeLucas, Stephen Barnes, Wei Wang, Guillermo J. Tearney, Landon Wilson, Patricia L. Jackson, Suman Karki, Kevin L. Kirk, Steven M. Rowe, S. Vamsee Raju, Vivian Y. Lin
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 56:99-108
Acquired cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction may contribute to chronic obstructive pulmonary disease pathogenesis and is a potential therapeutic target. We sought to determine the acute effects of cigarette smoke on
Autor:
Kartik Manne, Kevin Macon, Sthanam V.L. Narayana, Chen Chen, Olaf Schneewind, Vengadesan Krishnan
Publikováno v:
The Journal of Biological Chemistry
Background: Esp, a secreted protease of Staphylococcus epidermidis, blocks biofilm formation of Staphylococcus aureus and its ability to colonize human nares. Results: Esp cleaves autolysin, thereby preventing the release of staphylococcal DNA as bio
Autor:
Krishnan Vengadesan, Sthanam V.L. Narayana, Tadayuki Iwase, Yoshimitsu Mizunoe, Shinya Sugumoto, Kevin Macon
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 69:49-52
Esp, an extracellular serine protease from Staphylococcus epidermidis, has been shown to inhibit S. aureus biofilm formation and nasal colonization. The full-length 27 kDa pro-Esp was purified and digested with thermolysin to obtain mature Esp. The m
Autor:
D. Moore, Sthanam V.L. Narayana, John E. Volanakis, Karthe Ponnuraj, Yuanyuan Xu, Kevin Macon
Publikováno v:
Molecular Cell. 14(1):17-28
The C-terminal fragment, Bb, of factor B combines with C3b to form the pivotal C3-convertase, C3bBb, of alternative complement pathway. Bb consists of a von Willebrand factor type A (vWFA) domain that is structurally similar to the I domains of integ
Autor:
H. Jing, Kevin Macon, Sthanam V.L. Narayana, Lawrence J. DeLucas, John E. Volanakis, D. Moore
Publikováno v:
The EMBO Journal. 18:804-814
The crystal structure of profactor D, determined at 2.1 A resolution with an Rfree and an R-factor of 25.1 and 20.4%, respectively, displays highly flexible or disordered conformation for five regions: N-22, 71-76, 143-152, 187-193 and 215-223. A com
Autor:
Xin Ma, Arunima Mishra, Hung Ton-That, Prabhat Dwivedi, Alexandra B. Samal, Sthanam V.L. Narayana, Brandon J. Kim, Kelly S. Doran, Vengadesan Krishnan, Kevin Macon
The crystal structure of a 75 kDa central fragment of GBS104, a tip pilin from the 2063V/R strain of Streptococcus agalactiae (group B streptococcus; GBS), is reported. In addition, a homology model of the remaining two domains of GBS104 was built an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a581732551312e2ade92a91457fef888
https://europepmc.org/articles/PMC3663123/
https://europepmc.org/articles/PMC3663123/
We study the community structure of networks representing voting on resolutions in the United Nations General Assembly. We construct networks from the voting records of the separate annual sessions between 1946 and 2008 in three different ways: (1) b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef49d5eefe1c24f83674d23c0357ae5
Publikováno v:
Journal of Biological Chemistry. 267:25352-25358
Human C-reactive protein (CRP) can activate the classical pathway of complement and function as an opsonin only when it is complexed to an appropriate ligand. Most known CRP ligands bind to the phosphocholine (PCh)-binding site of the protein. In the
The second component of complement (C2) is a multi-domain serine protease that provides catalytic activity for the C3 and C5 convertases of the classical and lectin pathways of human complement. The formation of these convertases requires the Mg(2+)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f96619e4f675f85dbadfc02ed884857a
https://europepmc.org/articles/PMC2651757/
https://europepmc.org/articles/PMC2651757/
Network science is an interdisciplinary endeavor, with methods and applications drawn from across the natural, social, and information sciences. A prominent problem in network science is the algorithmic detection of tightly-connected groups of nodes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9767f7207b1fd78794de28f5700d3320