Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kevin M. Patrie"'
Autor:
Jessica A Lehoczky, Peedikayil E Thomas, Kevin M Patrie, Kailey M Owens, Lisa M Villarreal, Kenneth Galbraith, Joe Washburn, Craig N Johnson, Bryant Gavino, Alexander D Borowsky, Kathleen J Millen, Paul Wakenight, William Law, Margaret L Van Keuren, Galina Gavrilina, Elizabeth D Hughes, Thomas L Saunders, Lesil Brihn, Joseph H Nadeau, Jeffrey W Innis
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1003967 (2013)
Mouse early transposon insertions are responsible for ~10% of spontaneous mutant phenotypes. We previously reported the phenotypes and genetic mapping of Polypodia, (Ppd), a spontaneous, X-linked dominant mutation with profound effects on body plan m
Externí odkaz:
https://doaj.org/article/7e2168f239154d7b8e91247117543900
Autor:
Rakesh Verma, Iulia Kovari, Kevin M. Patrie, Deepak Nihalani, Abdul Soofi, Lawrence B. Holzman
Publikováno v:
Journal of Clinical Investigation. 116:1346-1359
A properly established and maintained podocyte intercellular junction, or slit diaphragm, is a necessary component of the selective permeability barrier of the kidney glomerulus. The observation that mutation or deletion of the slit diaphragm transme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9839a343e2979210e515ba58e373a84
https://doi.org/10.1172/jci27414
https://doi.org/10.1172/jci27414
Publikováno v:
Scopus-Elsevier
Neurofibromatosis type 1 (NF1) is among the most common inherited human diseases. The NF1 protein is a Ras-GTPase activating protein, positioning NF1 in important intracellular signaling pathways. Patients with mutations in the NF1 gene can develop b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d233a0d919f93c3d33f5740ef35ebfe
https://doi.org/10.1177/107385849700300614
https://doi.org/10.1177/107385849700300614
Publikováno v:
Journal of Biological Chemistry. 270:29018-29024
We have previously cloned and sequenced a newt keratinocyte growth factor receptor (KGFR) cDNA which exhibited a unique spatial and temporal expression pattern in the regenerating newt limb. In this report, we further characterize the biochemical and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9236abdf9c5ef7174b136646f12ec03f
https://doi.org/10.1074/jbc.270.48.29018
https://doi.org/10.1074/jbc.270.48.29018
Autor:
Kevin M. Patrie
Publikováno v:
Biochimica et biophysica acta. 1745(1)
The membrane-associated guanylate kinase protein, MAGI-1, has been shown to be a component of epithelial tight junctions in both Madin–Darby canine kidney cells and in intestinal epithelium. Because we have previously observed MAGI-1 expression in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd19f13e787f57c5f60e5f909952144c
https://pubmed.ncbi.nlm.nih.gov/16019084
https://pubmed.ncbi.nlm.nih.gov/16019084
Publikováno v:
The Journal of biological chemistry. 277(33)
In an attempt to find podocyte-expressed proteins that may interact with the tight junction protein MAGI-1, we screened a glomerulus-enriched cDNA library with a probe consisting of both WW domains of MAGI-1. One of the isolated clones contained two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672b3bef0de981ebc5758d1630afdb7d
https://pubmed.ncbi.nlm.nih.gov/12042308
https://pubmed.ncbi.nlm.nih.gov/12042308
Publikováno v:
Journal of the American Society of Nephrology : JASN. 12(4)
The transmembrane endocytic receptor glycoprotein 330/megalin (hereafter referred to as megalin) is localized to the apical membrane domain of epithelial cells, where it is involved in the uptake of proteins from extracellular sources. The cytoplasmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::571430b50f18d0a982365a733b5e4dc9
https://pubmed.ncbi.nlm.nih.gov/11274227
https://pubmed.ncbi.nlm.nih.gov/11274227
Publikováno v:
Biochemistry. 38(29)
Heparin potentiates the mitogenic activity of FGF-1 by increasing the affinity for its receptor and by extending its biological half-life. During the course of labeling human FGF-1 with Na(125)I and chloramine T, it was observed that the protein lost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b6148d46b1004c8ec636a722c9f84a
https://pubmed.ncbi.nlm.nih.gov/10413500
https://pubmed.ncbi.nlm.nih.gov/10413500
Publikováno v:
Growth factors (Chur, Switzerland). 14(1)
Recent studies have shown that fibroblast growth factors (FGF) play an important role in the diverse cellular mechanisms involved with vertebrate development. One system which has received a great deal of attention is the developing limb in part beca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ee4bd1b1616ef6a0cf8aa991f47644
https://pubmed.ncbi.nlm.nih.gov/9086327
https://pubmed.ncbi.nlm.nih.gov/9086327
Autor:
William D. Law, Paul Wakenight, Alexander D. Borowsky, Margaret L. Van Keuren, Jessica A. Lehoczky, Joseph H. Nadeau, Elizabeth D. Hughes, Kailey M. Owens, Lisa M. Villarreal, Bryant J. Gavino, Galina B. Gavrilina, Jeffrey W. Innis, Peedikayil E. Thomas, Lesil E Brihn, Kenneth Galbraith, Craig N. Johnson, Thomas L. Saunders, Kathleen J. Millen, Joe Washburn, Kevin M. Patrie
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1003967 (2013)
PLoS Genetics
PLoS Genetics
Mouse early transposon insertions are responsible for ∼10% of spontaneous mutant phenotypes. We previously reported the phenotypes and genetic mapping of Polypodia, (Ppd), a spontaneous, X-linked dominant mutation with profound effects on body plan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb507c2fd075b532a12c4889324b6cd
https://doi.org/10.1371/journal.pgen.1003967
https://doi.org/10.1371/journal.pgen.1003967