Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kevin M. Johnston"'
Autor:
Gregory A. Weiss, Joseph W. Ziller, Kevin M. Johnston, Derek B. Brown, Mark B. Richardson, Carlos A. Vasquez
Publikováno v:
The Journal of Organic Chemistry. 83:4525-4536
A reliable, scalable, cost-effective, and chromatography-free synthesis of 4-azido-L-phenylalanine beginning from L-phenylalanine is described. Investigations into the safety of the synthesis reveal that the Ullman-like Cu(I)-catalyzed azidation step
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785e87a1d3759f63b4ffaf59fc2b1fad
https://doi.org/10.1021/acs.joc.8b00270
https://doi.org/10.1021/acs.joc.8b00270
Autor:
Dmitry A. Fishman, Gregory A. Weiss, Kevin M. Johnston, Amanda J. H. Gilliam, Joshua N. Smith, Mark Balk, Sudipta Majumdar, Joshua M. Edgar, Andrew M. Gansmiller, Dylan Flather
Publikováno v:
Gilliam, AJH; Smith, JN; Flather, D; Johnston, KM; Gansmiller, AM; Fishman, DA; et al.(2016). Affinity-Guided Design of Caveolin-1 Ligands for Deoligomerization. JOURNAL OF MEDICINAL CHEMISTRY, 59(8), 4019-4025. doi: 10.1021/acs.jmedchem.5b01536. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/84m9p0sc
Journal of medicinal chemistry, vol 59, iss 8
Journal of medicinal chemistry, vol 59, iss 8
Caveolin-1 is a target for academic and pharmaceutical research due to its many cellular roles and associated diseases. We report peptide WL47 (1), a small, high-affinity, selective disrupter of caveolin-1 oligomers. Developed and optimized through s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937c3155b2c102d7bd2c8665ac90e660
https://doi.org/10.1021/acs.jmedchem.5b01536
https://doi.org/10.1021/acs.jmedchem.5b01536
Autor:
D. John Pierce, Mary L. Klein, Gary Knight, Douglas A. Boyce, William R. Singleton, Jason Bulluck, Stephen C. Trombulak, Craig Groves, James R. Strittholt, David M. Theobald, Kit Muller, Anne M. Trainor, Oswald J. Schmitz, Paul Beier, Kevin M. Johnston, Joshua J. Lawler
Publikováno v:
Natural Areas Journal. 35:190-203
As species' geographic ranges and ecosystem functions are altered in response to climate change, there is a need to integrate biodiversity conservation approaches that promote natural adaptation into land use planning. Successful conservation will ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da6fe8aee01ba2fcb13614004c81316e
https://doi.org/10.3375/043.035.0120
https://doi.org/10.3375/043.035.0120
Publikováno v:
Proceedings of the National Academy of Sciences. 100:11474-11477
National parks and bioreserves are key conservation tools used to protect species and their habitats within the confines of fixed political boundaries. This inflexibility may be their “Achilles' heel” as conservation tools in the face of emerging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60908dad34a16a6ba00a0d46d3eead78
https://doi.org/10.1073/pnas.1635115100
https://doi.org/10.1073/pnas.1635115100
Publikováno v:
Ecosphere. 3:art97
We examined potential impacts of climate change over the next century on eight mammal species of conservation concern in western Washington State, under four warming scenarios. Using two species distribution models, including a logistic regression-ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af39476da281ddc8a1e2c8d5d4bdc016
https://doi.org/10.1890/es12-00077.1
https://doi.org/10.1890/es12-00077.1
Autor:
Kevin M. Johnston
Publikováno v:
The GeoJournal Library ISBN: 9789048140718
The past twenty years have seen the development of certain computer-based applications that have changed the way people think about and perform their work. For example, word processing has revolutionised the way text is dealt with. No longer do the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be89d5845334422293abdde3a16b3b4b
https://doi.org/10.1007/978-94-017-1677-2_19
https://doi.org/10.1007/978-94-017-1677-2_19
Publikováno v:
BioScience. 53:1199
Current assessments of climate-change effects on ecosystems use two key approaches: (1) empirical synthesis and modeling of species range shifts and life-cycle processes that coincide with recent evidence of climate warming, from which scenarios of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7721c40277d200f368d9adb2f1abe82
https://doi.org/10.1641/0006-3568(2003)053[1199:ertgcc]2.0.co
https://doi.org/10.1641/0006-3568(2003)053[1199:ertgcc]2.0.co
Publikováno v:
Landscape Ecology. 2:101-110
Organisms may be constrained by the energetic costs incurred while obtaining resources in fragmented landscapes. We used a spatially neutral model of deer wintering habitat to evaluate the effects of landscape fragmentation on the aggregation of deer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc5decec270dd7f8c0b00bf482b0ce6b
https://doi.org/10.1007/bf00137154
https://doi.org/10.1007/bf00137154