Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Kevin M. Creamer"'
Publikováno v:
Nucleus, Vol 15, Iss 1 (2024)
Cytogenetic bands reflect genomic organization in large blocks of DNA with similar properties. Because banding patterns are invariant, this organization may often be assumed unimportant for genome regulation. Results here challenge that view. Finding
Externí odkaz:
https://doaj.org/article/d1ba3c936c7b4a0ba630189b2ca1017a
Autor:
Kailin L. Hsu, A. Alfred Chahine, Bhupender Yadav, Constance R. DiAngelo, Christopher T. Rossi, Kevin M. Creamer
Publikováno v:
Journal of Pediatric Surgery Case Reports, Vol 53, Iss , Pp - (2020)
A nine year-old boy with a complex medical history, including Phelan-McDermid syndrome, autism spectrum disorder, and focal epilepsy was admitted from Infectious Disease (ID) clinic for persistent fever for over three weeks. Laboratory studies were s
Externí odkaz:
https://doaj.org/article/a701072c5aec44a0a56206a4b3be6fac
Publikováno v:
G3 Genes|Genomes|Genetics. 12
Repetitive sequences including transposable elements and transposon-derived fragments account for nearly half of the human genome. While transposition-competent transposable elements must be repressed to maintain genomic stability, mutated and fragme
Publikováno v:
Cureus
Introduction Pediatric hospitalists are expected to lead resuscitative efforts for cardiopulmonary arrests, but the infrequency of these events and pediatric advanced life support (PALS) re-certifications are insufficient to maintain skill proficienc
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 33(2)
Here we provide a brief review of relevant background before presenting results of our investigation into the interplay between scaffold attachment factor A (SAF-A), chromatin-associated RNAs, and DNA condensation. SAF-A, also termed heterogenous nuc
Publikováno v:
Hospital Pediatrics. 10:820-822
The prevalence of cardiopulmonary arrest in pediatric inpatients is roughly 1 in every 1300 admissions.1 These code situations can be both clinically challenging and anxiety producing for the anticipated code team leaders. Hospitalists practicing at
Publikováno v:
Military medicine. 187(3-4)
Introduction The authors compared pediatric thoracic patients in the Joint Theatre Trauma Registry (JTTR) to those in the National Trauma Data Bank (NTDB) to assess differences in patient mortality rates and mortality risk accounting for age, injury
Autor:
Sreenath Shanker, Godwin Job, Olivia L George, Kevin M Creamer, Alaa Shaban, Janet F Partridge
Publikováno v:
PLoS Genetics, Vol 6, Iss 10, p e1001174 (2010)
Formation of centromeric heterochromatin in fission yeast requires the combined action of chromatin modifying enzymes and small RNAs derived from centromeric transcripts. Positive feedback mechanisms that link the RNAi pathway and the Clr4/Suv39h1 hi
Externí odkaz:
https://doaj.org/article/b5dc82926482455ba31cbcc84257455b
Publikováno v:
Mol Cell
Nuclear chromosomes transcribe far more RNA than required to encode protein. Here we investigate whether non-coding RNA broadly contributes to cytological-scale chromosome territory architecture. We develop a procedure that depletes soluble proteins,
Autor:
Csenge Gal, Lakxmi Subramanian, Robin C. Allshire, Karen M Moore, Alex J Whale, Konrad Paszkiewicz, Heather E. Murton, Kevin M. Creamer, Simon K. Whitehall, Sandra Codlin, Jürg Bähler, Nicholas A. Kent, Janet F. Partridge
Publikováno v:
EMBO Reports
Gal, C, Murton, H E, Subramanian, L, Whale, A J, Moore, K M, Paszkiewicz, K, Codlin, S, Bähler, J, Creamer, K M, Partridge, J F, Allshire, R C, Kent, N A & Whitehall, S K 2016, ' Abo1, a conserved bromodomain AAA-ATPase, maintains global nucleosome occupancy and organisation ', EMBO Reports, vol. 17, no. 1, pp. 79-93 . https://doi.org/10.15252/embr.201540476
Gal, C, Murton, H E, Subramanian, L, Whale, A J, Moore, K M, Paszkiewicz, K, Codlin, S, Bähler, J, Creamer, K M, Partridge, J F, Allshire, R C, Kent, N A & Whitehall, S K 2016, ' Abo1, a conserved bromodomain AAA-ATPase, maintains global nucleosome occupancy and organisation ', EMBO Reports, vol. 17, no. 1, pp. 79-93 . https://doi.org/10.15252/embr.201540476
Maintenance of the correct level and organisation of nucleosomes is crucial for genome function. Here, we uncover a role for a conserved bromodomain AAA-ATPase, Abo1, in the maintenance of nucleosome architecture in fission yeast. Cells lacking abo1+