Zobrazeno 1 - 10
of 491
pro vyhledávání: '"Kevin M. BRINDLE"'
Autor:
Nikita Sushentsev, Mary A. McLean, Anne Y. Warren, Arnold J. V. Benjamin, Cara Brodie, Amy Frary, Andrew B. Gill, Julia Jones, Joshua D. Kaggie, Benjamin W. Lamb, Matthew J. Locke, Jodi L. Miller, Ian G. Mills, Andrew N. Priest, Fraser J. L. Robb, Nimish Shah, Rolf S. Schulte, Martin J. Graves, Vincent J. Gnanapragasam, Kevin M. Brindle, Tristan Barrett, Ferdia A. Gallagher
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Your paper will be accompanied by the following editor’s summary. Please let us know if there are any inaccuracies: ‘Hyperpolarised ¹³C-MRI is used to image cancer metabolism. Here the authors use this technique in prostate cancer and show that
Externí odkaz:
https://doaj.org/article/e123d7318aa540b1a93cc058ead13ca5
Autor:
Ramona Woitek, Kevin M. Brindle
Publikováno v:
Diagnostics, Vol 13, Iss 13, p 2311 (2023)
One of the hallmarks of cancer is metabolic reprogramming, including high levels of aerobic glycolysis (the Warburg effect). Pyruvate is a product of glucose metabolism, and 13C-MR imaging of the metabolism of hyperpolarized (HP) [1-13C]pyruvate (HP
Externí odkaz:
https://doaj.org/article/a51a21d2ec2541c7acef08cc249815e6
Autor:
Tatiana J. Carneiro, Joana Pinto, Eva M. Serrao, António S. Barros, Kevin M. Brindle, Ana M. Gil
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Untargeted Nuclear Magnetic Resonance (NMR) metabolomics of polar extracts from the pancreata of a caerulin-induced mouse model of pancreatitis (Pt) and of a transgenic mouse model of pancreatic cancer (PCa) were used to find metabolic markers of Pt
Externí odkaz:
https://doaj.org/article/399346a3c6134faaadb8d2f0b107f229
Autor:
Zoltan Szucs, James Joseph, Tim J. Larkin, Bangwen Xie, Sarah E. Bohndiek, Kevin M. Brindle, André A. Neves
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-11 (2021)
Abstract Background Ductal carcinoma in situ (DCIS) is a non-invasive form of early breast cancer, with a poorly understood natural history of invasive transformation. Necrosis is a well-recognized adverse prognostic feature of DCIS, and non-invasive
Externí odkaz:
https://doaj.org/article/c0b167c206304a56b02e3735454d94b4
Autor:
Flaviu Bulat, Friederike Hesse, De-En Hu, Susana Ros, Connor Willminton-Holmes, Bangwen Xie, Bala Attili, Dmitry Soloviev, Franklin Aigbirhio, Finian. J. Leeper, Kevin M. Brindle, André A. Neves
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Introduction Trialing novel cancer therapies in the clinic would benefit from imaging agents that can detect early evidence of treatment response. The timing, extent and distribution of cell death in tumors following treatment can give an in
Externí odkaz:
https://doaj.org/article/e21d4f55168b4903adafd4356cd7f69c
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100608- (2021)
Summary: 13C nuclear spin hyperpolarization can increase the sensitivity of detection in an MRI experiment by more than 10,000-fold. 13C magnetic resonance spectroscopic imaging (MRSI) of hyperpolarized 13C label exchange between injected [1-13C]pyru
Externí odkaz:
https://doaj.org/article/d060b43d8e6d465fbe71e6aea02c48c3
Autor:
Frank Riemer, Pippa G Corrie, Catherine Booth, Ferdia A Gallagher, Kevin M Brindle, Martin J Graves, Arthur Lewis, Doreen Lau, Mary A McLean, Andrew N Priest, Andrew B Gill, Francis Scott, Ilse Patterson, Bruno Carmo, Joshua D Kaggie, Amy Frary, Doreen Milne, Michal Sulikowski, Lee Brown, Jean-Martin Lapointe, Luigi Aloj
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/dcf7672568004450b3bd5e066f9c38eb
Publikováno v:
Progress in Nuclear Magnetic Resonance Spectroscopy. :39-51
Deuterium metabolic imaging (DMI) is an emerging clinically-applicable technique for the non-invasive investigation of tissue metabolism. The generally short T1 values of 2H-labeled metabolites in vivo can compensate for the relatively low sensitivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769eb8e9f425c35bc6273135c683cb90
https://doi.org/10.1016/j.pnmrs.2023.02.002
https://doi.org/10.1016/j.pnmrs.2023.02.002
Autor:
Nikita Sushentsev, Mary A. McLean, Anne Y. Warren, Arnold J. V. Benjamin, Cara Brodie, Amy Frary, Andrew B. Gill, Julia Jones, Joshua D. Kaggie, Benjamin W. Lamb, Matthew J. Locke, Jodi L. Miller, Ian G. Mills, Andrew N. Priest, Fraser J. L. Robb, Nimish Shah, Rolf F. Schulte, Martin J. Graves, Vincent J. Gnanapragasam, Kevin M. Brindle, Tristan Barrett, Ferdia A. Gallagher
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/a09e47bcae5743258611ebc46d4f4615
Autor:
Florent Mouliere, Richard Mair, Dineika Chandrananda, Francesco Marass, Christopher G Smith, Jing Su, James Morris, Colin Watts, Kevin M Brindle, Nitzan Rosenfeld
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 12, Pp 1-6 (2018)
Abstract Glioma is difficult to detect or characterize using current liquid biopsy approaches. Detection of cell‐free tumor DNA (cftDNA) in cerebrospinal fluid (CSF) has been proposed as an alternative to detection in plasma. We used shallow whole
Externí odkaz:
https://doaj.org/article/1ce875fdfe6e48c6ad6369793925f477