Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kevin M. Arnold"'
Publikováno v:
Journal of Biological Chemistry. 286:24694-24701
Rtt109 is a yeast histone acetyltransferase (HAT) that associates with histone chaperones Asf1 and Vps75 to acetylate H3K56, H3K9, and H3K27 and is important in DNA replication and maintaining genomic integrity. Recently, mass spectrometry and struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7ced43056e36c94522e11752123c73
https://doi.org/10.1074/jbc.m111.251579
https://doi.org/10.1074/jbc.m111.251579
Publikováno v:
ChemBioChem. 12:290-298
Post-translational modifications of histones elicit structural and functional changes within chromatin that regulate various epigenetic processes. Epigenetic mechanisms rely on enzymes whose activities are driven by co-enzymes and metabolites from in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15c317372f0b9186ac845a01f0e6eed
https://doi.org/10.1002/cbic.201000438
https://doi.org/10.1002/cbic.201000438
Autor:
Emily A. Olsen, David A. Kocisko, Kil Sun Lee, Kevin M. Arnold, Nadine Bertholet, Jean-Marc Juteau, Byron Caughey, Andrew Vaillant, Richard E. Race
Publikováno v:
Antimicrobial Agents and Chemotherapy. 50:1034-1044
Although transmissible spongiform encephalopathies (TSEs) are incurable, a key therapeutic approach is prevention of conversion of the normal, protease-sensitive form of prion protein (PrP-sen) to the disease-specific protease-resistant form of prion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98b7fe3d7cf82a1d1571386b6fefe8c
https://doi.org/10.1128/aac.50.3.1034-1044.2006
https://doi.org/10.1128/aac.50.3.1034-1044.2006
Autor:
Kevin M. Arnold, Catharine B. Stack, Krishnan Nandabalan, Dennis W. McGraw, Connie M. Drysdale, J. Claiborne Stephens, Stephen B. Liggett, Gualberto Ruaño, Richard S. Judson
Publikováno v:
Proceedings of the National Academy of Sciences. 97:10483-10488
The human β 2 -adrenergic receptor gene has multiple single-nucleotide polymorphisms (SNPs), but the relevance of chromosomally phased SNPs (haplotypes) is not known. The phylogeny and the in vitro and in vivo consequences of variations in the 5′
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b838ef5ca1513691e7f1f18d6b206cdd
https://doi.org/10.1073/pnas.97.19.10483
https://doi.org/10.1073/pnas.97.19.10483
Publikováno v:
ChemInform. 42
Post-translational modifications of histones elicit structural and functional changes within chromatin that regulate various epigenetic processes. Epigenetic mechanisms rely on enzymes whose activities are driven by coenzymes and metabolites from int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8626f0a5bf634c38e3cff351c5f84367
https://doi.org/10.1002/chin.201119267
https://doi.org/10.1002/chin.201119267
Publikováno v:
Biochemistry. 50(5)
Eukaryotic DNA is packaged in the nucleoprotein structure chromatin, the smallest component of which is the nucleosome core particle (NCP). Each core particle consists of 147 bp of DNA wrapped 1.7 times around an octamer of the four canonical histone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c379d0980bc3167797be5e5ef0f7e0
https://pubmed.ncbi.nlm.nih.gov/21182309
https://pubmed.ncbi.nlm.nih.gov/21182309
Autor:
Brittany N. Albaugh, Scott E. Lindner, Kevin M. Arnold, John M. Denu, Kenneth A. Satyshur, Erin M. Kolonko, Paul D. Kaufman, Yuanyuan Chen, James L. Keck
Most histone acetyltransferases (HATs) function as multisubunit complexes in which accessory proteins regulate substrate specificity and catalytic efficiency. Rtt109 is a particularly interesting example of a HAT whose specificity and catalytic activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd6eb1bd10c4c0d9a059573009fac63
https://europepmc.org/articles/PMC2996700/
https://europepmc.org/articles/PMC2996700/
Autor:
Byron Caughey, David A. Kocisko, Lynne D. Raymond, Kevin M. Arnold, Abbi L. Engel, Emily A. Olsen, Didier Vilette, Kristin Harbuck
Publikováno v:
Neuroscience Letters
Neuroscience Letters, Elsevier, 2005, 388 (2), pp.106-111. ⟨10.1016/j.neulet.2005.06.053⟩
Neuroscience Letters, Elsevier, 2005, 388 (2), pp.106-111. ⟨10.1016/j.neulet.2005.06.053⟩
International audience; The transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative diseases. A primary therapeutic target for TSE intervention has been a protease-resistant form of prion protein known as PrPSc or PrP-res. In vit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::984161cc66250b5b14749607b8590ded
https://hal.inrae.fr/hal-02680208
https://hal.inrae.fr/hal-02680208
Autor:
A. Madan Kumar, Chad Messer, Julie . Choi, Ge Zhang, Connie M. Drysdale, Vincent P. Schulz, Krishnan Nandabalan, Ruhong Jiang, Min Seob Lee, Beena Koshy, Gualberto Ruaño, Debra A. Tanguay, Anne Chew, Theodore S. Kalbfleisch, J. Claiborne Stephens, Kevin M. Arnold, Tara Acharya, Julie A. Schneider, Jin-Hua Han, Chuanbo Xu, Scott E. Stanley, Jicheng Duan, Sandra L. Shaner, Richard S. Judson, Gerald F. Vovis, William R. Newell, Janet L. Carr, Andreas Windemuth
Publikováno v:
Science (New York, N.Y.). 293(5529)
Variation within genes has important implications for all biological traits. We identified 3899 single nucleotide polymorphisms (SNPs) that were present within 313 genes from 82 unrelated individuals of diverse ancestry, and we organized the SNPs int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::484bcbf1384ad38d88a9bf64c49fe5ae
https://pubmed.ncbi.nlm.nih.gov/11452081
https://pubmed.ncbi.nlm.nih.gov/11452081