Zobrazeno 1 - 10
of 534
pro vyhledávání: '"Kevin M. Ryan"'
Autor:
Aaron O’Sullivan, Enrico Spoletti, Steven A. Ross, Matteo Lusi, Dennis Douroumis, Kevin M. Ryan, Luis Padrela
Publikováno v:
ACS Omega, Vol 9, Iss 27, Pp 29710-29722 (2024)
Externí odkaz:
https://doaj.org/article/f5996a7e3f6c48bcb44dbd8ccc692408
Publikováno v:
Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)
Abstract Semiconductor nanocrystals (NCs) are promising materials for various applications. Two of four recently identified CuαZnβSnγSeδ (CZTSe) domains demonstrate metallic character, while the other two exhibit semiconductor character. The pres
Externí odkaz:
https://doaj.org/article/c393b80e00b84f5cb141541dfd12b246
Autor:
Elżbieta Kania, Jaclyn S. Long, David G. McEwan, Kirsten Welkenhuyzen, Rita La Rovere, Tomas Luyten, John Halpin, Evy Lobbestael, Veerle Baekelandt, Geert Bultynck, Kevin M. Ryan, Jan B. Parys
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-14 (2023)
Abstract Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most common genetic cause of Parkinson’s disease (PD), with growing importance also for Crohn’s disease and cancer. LRRK2 is a large and complex protein possessing both G
Externí odkaz:
https://doaj.org/article/ac990b44ebe440e7985118a7bf10125c
Autor:
Valentin J. A. Barthet, Kevin M. Ryan
Publikováno v:
Autophagy Reports, Vol 1, Iss 1, Pp 170-174 (2022)
Macroautophagy/autophagy is a conserved catabolic process that delivers intracellular materials to lysosomes for degradation. This process promotes cell survival by maintaining cellular homeostasis and supplying substrates to produce energy during nu
Externí odkaz:
https://doaj.org/article/39ca68d79311445f8694af162d9edd9a
Autor:
Kevin M. Ryan
Publikováno v:
Molecular Oncology, Vol 16, Iss 1, Pp 3-7 (2022)
Externí odkaz:
https://doaj.org/article/f2d211a8cf7d41e3b8d3130e7ce206ce
Publikováno v:
Molecular Oncology, Vol 17, Iss 6, Pp 919-920 (2023)
The formation of organisations and societies within all areas of scientific research facilitates the bringing together of researchers in a given field and serves to aid communication, collaboration, progress of science and career development. Even gr
Externí odkaz:
https://doaj.org/article/7dd4388185df47cd97eb3656b48eb6a5
Autor:
Kevin M. Ryan
Publikováno v:
Molecular Oncology, Vol 16, Iss 12, Pp 2297-2299 (2022)
Externí odkaz:
https://doaj.org/article/58d9e738bd564b9fb09b3621c9b30cb2
Autor:
Anne-Louise Latif, Ashley Newcombe, Sha Li, Kathryn Gilroy, Neil A. Robertson, Xue Lei, Helen J. S. Stewart, John Cole, Maria Terradas Terradas, Loveena Rishi, Lynn McGarry, Claire McKeeve, Claire Reid, William Clark, Joana Campos, Kristina Kirschner, Andrew Davis, Jonathan Lopez, Jun-ichi Sakamaki, Jennifer P. Morton, Kevin M. Ryan, Stephen W. G. Tait, Sheela A. Abraham, Tessa Holyoake, Brian Higgins, Xu Huang, Karen Blyth, Mhairi Copland, Timothy J. T. Chevassut, Karen Keeshan, Peter D. Adams
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
MDM2 and BET inhibitors have shown efficacy in AML treatment. Here, the authors show that the two compounds can synergize through both p53 protein stabilization and inhibition of BRD4-mediated repression of p53 target genes.
Externí odkaz:
https://doaj.org/article/4058dbf2924543a399c2f17c8fd2a6ad
Autor:
Simone Torretta, Alessandra Scagliola, Luisa Ricci, Francesco Mainini, Sabrina Di Marco, Ivan Cuccovillo, Anna Kajaste-Rudnitski, David Sumpton, Kevin M. Ryan, Simone Cardaci
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Mannose is present at trace levels in blood and regulates cancer growth. Here the authors show that supraphysiological levels of mannose can also regulate macrophages, limiting their production of IL-1β and increasing resistance of mice to LPS-induc
Externí odkaz:
https://doaj.org/article/33a11b42ec3643e18f2c5585a702657e
Autor:
Vivek Verma, Simone Bordignon, Michele R. Chierotti, Monica Lestari, Kieran Lyons, Luis Padrela, Kevin M. Ryan, Matteo Lusi
Publikováno v:
IUCrJ, Vol 7, Iss 6, Pp 1124-1130 (2020)
Multidrug products enable more effective therapies and simpler administration regimens, provided that a stable formulation is prepared, with the desired composition. In this view, solid solutions have the advantage of combining the stability of a sin
Externí odkaz:
https://doaj.org/article/ecbf8e7fceab46978d920b4198abe11f