Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Kevin M Vannella"'
Autor:
Kevin M Vannella, Luke Barron, Lee A Borthwick, Kristen N Kindrachuk, Prakash Babu Narasimhan, Kevin M Hart, Robert W Thompson, Sandra White, Allen W Cheever, Thirumalai R Ramalingam, Thomas A Wynn
Publikováno v:
PLoS Pathogens, Vol 10, Iss 9, p e1004372 (2014)
Mice expressing a Cre recombinase from the lysozyme M-encoding locus (Lyz2) have been widely used to dissect gene function in macrophages and neutrophils. Here, we show that while naïve resident tissue macrophages from IL-4Rαf(lox/delta)LysM(Cre) m
Externí odkaz:
https://doaj.org/article/f6ebeffb5bf74f55ad6766d2236a5225
Autor:
J Philip Nance, Kevin M Vannella, Danielle Worth, Clément David, David Carter, Shahani Noor, Cedric Hubeau, Lori Fitz, Thomas E Lane, Thomas A Wynn, Emma H Wilson
Publikováno v:
PLoS Pathogens, Vol 8, Iss 11, p e1002990 (2012)
Chronic infections represent a continuous battle between the host's immune system and pathogen replication. Many protozoan parasites have evolved a cyst lifecycle stage that provides it with increased protection from environmental degradation as well
Externí odkaz:
https://doaj.org/article/8a5cbad8be0c4e56abe471ec055b1d30
Autor:
Luis J. Perez-Valencia, Kevin M. Vannella, Marcos J. Ramos-Benitez, Junfeng Sun, Mones Abu-Asab, David W. Dorward, Keytam S. Awad, Andrew Platt, Eliana Jacobson, Jason Kindrachuk, Daniel S. Chertow
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107323- (2023)
Summary: Lymphocyte depletion is a distinctive feature of Ebola virus (EBOV) disease. The ectodomain of EBOV glycoprotein (GP) is cleaved off the surface of infected cells into circulation as shed GP. To test the hypothesis that shed GP induces lymph
Externí odkaz:
https://doaj.org/article/1e7999ed972e4794bc00999e02c13e6e
Autor:
Kaia E. Barth, Natasha Spottiswoode, Charlotte Hurabielle, Lakshmi Subbaraj, COMET Consortium, Carolyn S. Calfee, Michael A. Matthay, Sarah French, Andrew Connolly, Stephen M. Hewitt, Kevin M. Vannella, Christopher Barnett, Charles R. Langelier, Sarah Patterson
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
ImportanceMultisystem inflammatory syndrome in adults (MIS-A) is a poorly understood complication of SARS-CoV-2 infection with significant morbidity and mortality.ObjectiveIdentify clinical, immunological, and histopathologic features of MIS-A to imp
Externí odkaz:
https://doaj.org/article/6545ff54e0cd48c0ac63dd25066a0f97
Autor:
Andrew P. Platt, Benjamin T. Bradley, Nadia Nasir, Sydney R. Stein, Sabrina C. Ramelli, Marcos J. Ramos-Benitez, James M. Dickey, Madeleine Purcell, Shreya Singireddy, Nicole Hays, Jocelyn Wu, Katherine Raja, Ryan Curto, Stephen J. Salipante, Claire Chisholm, Stephanie Carnes, Desiree A. Marshall, Brad T. Cookson, Kevin M. Vannella, Ronson J. Madathil, Shahabuddin Soherwardi, Michael T. McCurdy, Kapil K. Saharia, Joseph Rabin, NIH COVID-19 Autopsy Consortium, Alison Grazioli, David E. Kleiner, Stephen M. Hewitt, Joshua A. Lieberman, Daniel S. Chertow
Publikováno v:
Pathogens, Vol 12, Iss 7, p 932 (2023)
Bacterial and fungal co-infections are reported complications of coronavirus disease 2019 (COVID-19) in critically ill patients but may go unrecognized premortem due to diagnostic limitations. We compared the premortem with the postmortem detection o
Externí odkaz:
https://doaj.org/article/53657f01d4ef40ee97de0ac8d53b14e7
Autor:
Kevin M. Vannella, Cihan Oguz, Sydney R. Stein, Stefania Pittaluga, Esra Dikoglu, Arjun Kanwal, Sabrina C. Ramelli, Thomas Briese, Ling Su, Xiaolin Wu, Marcos J. Ramos-Benitez, Luis J. Perez-Valencia, Ashley Babyak, Nu Ri Cha, Joon-Yong Chung, Kris Ylaya, Ronson J. Madathil, Kapil K. Saharia, Thomas M. Scalea, Quincy K. Tran, Daniel L. Herr, David E. Kleiner, Stephen M. Hewitt, Luigi D. Notarangelo, Alison Grazioli, Daniel S. Chertow
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
A 26-year-old otherwise healthy man died of fulminant myocarditis. Nasopharyngeal specimens collected premortem tested negative for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Histopathological evaluation of the heart showed myocard
Externí odkaz:
https://doaj.org/article/6ba222e1e9c649928771644cc0bb6220
Autor:
Kapil K. Saharia, Sabrina C. Ramelli, Sydney R. Stein, Allison E. Roder, Allie Kreitman, Stephanie Banakis, Joon-Yong Chung, Peter D. Burbelo, Manmeet Singh, Robert M. Reed, Vipul Patel, Joseph Rabin, Alexander S. Krupnick, Jeffrey I. Cohen, Emmie de Wit, Elodie Ghedin, Stephen M. Hewitt, Kevin M. Vannella, Daniel S. Chertow, Alison Grazioli
Publikováno v:
American Journal of Transplantation. 23:101-107
Autor:
H. Nida Sen, Kevin M. Vannella, Yujuan Wang, Joon-Yong Chung, Shilpa Kodati, Sabrina C. Ramelli, Jung Wha Lee, Paola Perez, Sydney R. Stein, Alison Grazioli, James M. Dickey, Kris Ylaya, Manmeet Singh, Kwe Claude Yinda, Andrew Platt, Marcos J. Ramos-Benitez, Christa Zerbe, Vincent J. Munster, Emmie de Wit, Blake M. Warner, Daniel L. Herr, Joseph Rabin, Kapil K. Saharia, David E. Kleiner, Stephen M. Hewitt, Chi-Chao Chan, Daniel S. Chertow, Andrew P. Platt, Shelly J. Curran, Ashley L. Babyak, Luis Perez Valencia, Mary E. Richert, Willie J. Young, Sarah P. Young, Billel Gasmi, Michelly Sampaio De Melo, Sabina Desar, Saber Tadros, Nadia Nasir, Xueting Jin, Sharika Rajan, Esra Dikoglu, Neval Ozkaya, Stefania Pittaluga, Grace Smith, Elizabeth R. Emanuel, Brian Kelsall, Justin A. Olivera, Megan Blawas, Nicole Hays, Madeleine Purcell, Shreya Singireddy, Jocelyn Wu, Katherine Raja, Ryan Curto, Jean Chung, Amy Borth, Kimberly Bowers, Anne Weichold, Paula Minor, Mirahmad Moshref, Emily Kelly, Mohammad M. Sajadi, Thomas M. Scalea, Douglas Tran, Ronson J. Madathil, Siamak Dahi, Kristopher B. Deatrick, Eric M. Krause, Joseph A. Herrold, Ali Tabatabai, Eric Hochberg, Christopher Cornachione, Andrea R. Levine, Justin E. Richards, John Elder, Allen Burke, Michael A. Mazzeffi, Robert Christenson, Zackary Chancer, Mustafa Abdulmahdi, Sabrina Sopha, Tyler Goldberg, Shahabuddin Soherwardi, Yashvir Sangwan, Michael T. McCurdy, Kristen Sudano, Diane Blume, Bethany Radin, Madhat Arnouk, James W. Eagan
Publikováno v:
The American Journal of Pathology.
Autor:
Alexandra F. Freeman, Majid Kazemian, Jack A. Bibby, Daniel Chauss, Daniel S. Chertow, Michail S. Lionakis, Reuben McGregor, Tilo Freiwald, Nehal N. Mehta, Heather L. Teague, Luopin Wang, Audrey Kelly, Behdad Afzali, Estefania Nova-Lamperti, Kevin M. Vannella, Amna Malik, Daniella M. Schwartz, Bingyu Yan, Claudia Kemper, Didier Portilla, Giovanna Lombardi, Marcos J Ramos-Benitez, Susan D. John, Nichola Cooper, Arian Laurence, Paul Lavender, Erin E. West, Zonghao Zhang, Dhaneshwar Kumar
Publikováno v:
Nature immunology
The molecular mechanisms governing orderly shutdown and retraction of CD4+ type 1 helper T (TH1) cell responses remain poorly understood. Here we show that complement triggers contraction of TH1 responses by inducing intrinsic expression of the vitam
Autor:
Marcos J. Ramos-Benitez, Jeffrey R. Strich, Sara Alehashemi, Sydney Stein, Andre Rastegar, Adriana Almeida de Jesus, Farzana Bhuyan, Sabrina Ramelli, Ashley Babyak, Luis Perez-Valencia, Kevin M. Vannella, Gabrielle Grubbs, Surender Khurana, Robin Gross, Kyra Hadley, Janie Liang, Steven Mazur, Elena Postnikova, Seth Warner, Michael R. Holbrook, Lindsay M. Busch, Blake Warner, Willard Applefeld, Sarah Warner, Sameer S Kadri, Richard T Davey, Raphaela Goldbach-Mansky, Daniel S. Chertow
Publikováno v:
medRxiv : the preprint server for health sciences.
Understanding early innate immune responses to coronavirus disease 2019 (COVID–19) is crucial to developing targeted therapies to mitigate disease severity. Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infection elicits interferon exp