Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kevin M Ileka"'
Autor:
Jia Zang, Kevin M. Ileka, Jonathan G. Shackman, Peter Tattersall, Elizabeth M. Yuill, Thomas E. La Cruz, Jieming Li
Publikováno v:
Organic Process Research & Development. 25:1431-1439
Drug substance stability-indicating methods (SIMs) must undergo a litany of optimization and robustness stresses to ensure that the methods can be successfully validated, transferred, and routinely...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cac4858bd5591a8c48e5bfc828b89c50
https://doi.org/10.1021/acs.oprd.1c00121
https://doi.org/10.1021/acs.oprd.1c00121
High-molecular weight impurity screening by size-exclusion chromatography on a reversed-phase column
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 196:113908
Monitoring polymerization events leading to the discovery of new high-molecular weight (MW) impurities is challenging during chemical syntheses of active pharmaceutical ingredients. Employing reversed-phase chromatography (RPC) stationary phases (SPs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a1d017ef698cc5b0e3a4f45784d138
https://doi.org/10.1016/j.jpba.2021.113908
https://doi.org/10.1016/j.jpba.2021.113908
Autor:
Brent R. Martin, Nicholas B. Borotto, Christina A T M B Tom, Kristina Håkansson, Kevin M Ileka
Tandem mass spectrometry (MS/MS) is the primary method for discovering, identifying, and localizing post-translational modifications (PTMs) in proteins. However, conventional positive ion mode collision induced dissociation (CID)-based MS/MS often fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481fadcbc38ea0c8766233636c0a50e0
https://europepmc.org/articles/PMC6235672/
https://europepmc.org/articles/PMC6235672/
