Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Kevin M Collins"'
Publikováno v:
PLoS Genetics, Vol 15, Iss 1, p e1007896 (2019)
Neurons typically release both a small-molecule neurotransmitter and one or more neuropeptides, but how these two types of signal from the same neuron might act together remains largely obscure. For example, serotonergic neurons in mammalian brain ex
Externí odkaz:
https://doaj.org/article/9eb0ea2d71334080b05216964429fe83
Publikováno v:
PLoS Genetics, Vol 13, Iss 4, p e1006697 (2017)
Animal behaviors are often composed of distinct alternating behavioral states. Neuromodulatory signals are thought to be critical for establishing stable behavioral states and for orchestrating transitions between them. However, we have only a limite
Externí odkaz:
https://doaj.org/article/308604eadaaf4337ad7d5b6162b53738
Autor:
Kevin M Collins, Addys Bode, Robert W Fernandez, Jessica E Tanis, Jacob C Brewer, Matthew S Creamer, Michael R Koelle
Publikováno v:
eLife, Vol 5 (2016)
Like many behaviors, Caenorhabditis elegans egg laying alternates between inactive and active states. To understand how the underlying neural circuit turns the behavior on and off, we optically recorded circuit activity in behaving animals while mani
Externí odkaz:
https://doaj.org/article/ebe22fcff2cc4706943a6e372af82db4
Publikováno v:
eLife, Vol 2 (2013)
The diverse cell types and the precise synaptic connectivity between them are the cardinal features of the nervous system. Little is known about how cell fate diversification is linked to synaptic target choices. Here we investigate how presynaptic n
Externí odkaz:
https://doaj.org/article/fb92d817efaa4a188727550dab8a2c15
Autor:
Emmanuel Medrano, Kevin M. Collins
Publikováno v:
Current Biology.
Autor:
Alan Hastings, Bo Zhang, Wei-Ming Ni, Kevin M. Collins, Rossana Signorelli, Lu Zhai, Donald L. DeAngelis, Zhiyuan Fu, Yuan Lou, King-Yeung Lam
Publikováno v:
Ecol Lett
Understanding mechanisms of coexistence is a central topic in ecology. Mathematical analysis of models of competition between two identical species moving at different rates of symmetric diffusion in heterogeneous environments show that the slower mo
Publikováno v:
J Neurosci
Successful execution of behavior requires coordinated activity and communication between multiple cell types. Studies using the relatively simple neural circuits of invertebrates have helped to uncover how conserved molecular and cellular signaling e
Publikováno v:
Genetics
Activated Gαq signals through phospholipase-Cβ and Trio, a Rho GTPase exchange factor (RhoGEF), but how these distinct effector pathways promote cellular responses to neurotransmitters like serotonin remains poorly understood. We used the egg-layin
Autor:
Mary O. Olagunju, Addys Bode, Kevin M. Collins, Christian Falgons, Catherine J. Munro, Marc R. Knecht, Sana Chaudhry, Carla Bobé, Michelle A. Nguyen, Manuel E. Portela
Publikováno v:
Environmental Science: Nano. 7:645-655
Previous work has shown that spherical CuO nanomaterials show negative effects on cell and animal physiology. The biological effects of Cu2O materials, which possess unique chemical features compared to CuO nanomaterials and can be synthesized in a s
Autor:
Mattingly K. Bartole, Rossana Signorelli, Sana Chaudhry, Lijun Kang, Richard J. Kopchock, Christian Guijarro, Bhavya Ravi, Joshua M. Kaplan, Jian Zhao, Kevin M. Collins
Publikováno v:
Genetics
Egg laying in the nematode worm Caenorhabditis elegans is a two-state behavior modulated by internal and external sensory input. We have previously shown that homeostatic feedback of embryo accumulation in the uterus regulates bursting activity of th