Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kevin M Braunscheidel"'
Autor:
Kevin M. Braunscheidel, George Voren, Christie D. Fowler, Qun Lu, Alexander Kuryatov, Michael D. Cameron, Ines Ibañez-Tallon, Jon M. Lindstrom, Theodore M. Kamenecka, Paul J. Kenny
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
BackgroundMost smokers attempting to quit will quickly relapse to tobacco use even when treated with the most efficacious smoking cessation agents currently available. This highlights the need to develop effective new smoking cessation medications. E
Externí odkaz:
https://doaj.org/article/13755185d072421ba960bb627e47c5e1
Publikováno v:
Addiction Neuroscience, Vol 5, Iss , Pp 100059- (2023)
Substance use disorder (SUD) is characterized, in part, by lack of control over drug seeking and taking. The prefrontal cortex (PFC) is highly involved in control of behavior and deficits in PFC structure and function have been demonstrated in clinic
Externí odkaz:
https://doaj.org/article/f646cc128bb145b9a050241c00961c0f
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Inhalants, including volatile organic solvents such as toluene, continue to be one of the most prevalent, and often first substances abused by adolescents. Like other drugs of abuse, toluene affects the function of neurons within key brain reward cir
Externí odkaz:
https://doaj.org/article/fae28a4a9d5c43269df833977b407f66
Autor:
Todd B. Nentwig, Dylan T. Vaughan, Kevin M. Braunscheidel, Brittney D. Browning, John J. Woodward, L. Judson Chandler
Publikováno v:
Neuropsychopharmacology. 47:2123-2131
The lateral habenula (LHb) is an epithalamic nuclei that has been shown to signal the aversive properties of ethanol. The present study tested the hypothesis that activity of the LHb is required for the acquisition and/or expression of dependence-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8efb2363f1e5c7a7f56b189fe459205f
https://doi.org/10.1038/s41386-022-01357-7
https://doi.org/10.1038/s41386-022-01357-7
Publikováno v:
Psychopharmacology (Berl)
Drugs of abuse including cannabis and inhalants impair risk/reward decision making. Cannabis use is often concurrent with inhalant intoxication; yet, preclinical studies investigating the role of endocannabinoids in inhalant misuse are limited. To ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54363c702a6442f2f9c0107cba34d792
https://doi.org/10.1007/s00213-021-05914-8
https://doi.org/10.1007/s00213-021-05914-8
Autor:
Lauren Wills, Jessica L. Ables, Kevin M. Braunscheidel, Stephanie P.B. Caligiuri, Karim S. Elayouby, Clementine Fillinger, Masago Ishikawa, Janna K. Moen, Paul J. Kenny
Publikováno v:
Pharmacological reviews. 74(1)
Neuronal nicotinic acetylcholine receptors (nAChRs) regulate the rewarding actions of nicotine contained in tobacco that establish and maintain the smoking habit. nAChRs also regulate the aversive properties of nicotine, sensitivity to which decrease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0b93b839a49572d1c50f279c7e8f94f
https://pubmed.ncbi.nlm.nih.gov/35017179
https://pubmed.ncbi.nlm.nih.gov/35017179
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 14 (2020)
Frontiers in Neuroscience, Vol 14 (2020)
Inhalants, including volatile organic solvents such as toluene, continue to be one of the most prevalent, and often first substances abused by adolescents. Like other drugs of abuse, toluene affects the function of neurons within key brain reward cir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d630bc53d4b7b2c733ac926e33584c
https://doi.org/10.3389/fnins.2020.00880
https://doi.org/10.3389/fnins.2020.00880
Autor:
Patrick J. Mulholland, Kevin M. Braunscheidel, John J. Woodward, Justin T. Gass, Stan B. Floresco
Publikováno v:
Neurobiology of Learning and Memory. 144:136-146
While the psychoactive inhalant toluene causes behavioral effects similar to those produced by other drugs of abuse, the persistent behavioral and anatomical abnormalities induced by toluene exposure are not well known. To mimic human “binge-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ad0f5eac712f22920212bc74da3fc2
https://doi.org/10.1016/j.nlm.2017.07.007
https://doi.org/10.1016/j.nlm.2017.07.007
Autor:
Linsey Passarella, Patrick J. Mulholland, Kevin M. Braunscheidel, Erin S. Calipari, Jennifer A. Rinker, Wesley N. Wayman, Dominic A. Gioia, Michaela Hoffman, John J. Woodward
Drugs of abuse are known to alter activity in areas of brain associated with reward, cognition and decision making. Changes in neural activity in these regions that follow repeated exposures to abused substances may underlie the development of addict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b44ef47953e7f87723009ca37eced2
Autor:
Jennifer A. Martin, Rachael L. Neve, David M. Dietz, Aaron Caccamise, Zi-Jun Wang, Monica S. Humby, Diane M. Damez-Werno, Kevin M Braunscheidel, Amy M. Gancarz, Gabrielle L. Schroeder, Lauren E. Mueller, Karen C. Dietz
Publikováno v:
Nature neuroscience
Cocaine addiction is a life-long relapsing disorder that results from long-term adaptations within the brain. We find that Activin-receptor signaling, including the transcription factor Smad3, is upregulated in the rat nucleus accumbens shell followi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2bcf1bd9d0769dc99fa84832729bd98
https://doi.org/10.1038/nn.4036
https://doi.org/10.1038/nn.4036