Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kevin Lee Stark"'
Autor:
Dimitry M. Danilenko, Brian Varnum, Jerry M. Housman, Randall M. Rossi, Karen A. Augustine, Eugene Medlock, Gwenyth Van, Kevin Lee Stark
Publikováno v:
Journal of Cellular Physiology. 181:433-447
The axl tyrosine kinase receptor is aberrantly expressed on myeloid cells of many individuals afflicted with chronic myelogenous leukemia (CML) and other myeloid leukemias. Although previous studies demonstrated this kinase to have oncogenic potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21af567c27de0ab66f62acc3bcabba6e
https://doi.org/10.1002/(sici)1097-4652(199912)181:3<433::aid-jcp7>3.0.co
https://doi.org/10.1002/(sici)1097-4652(199912)181:3<433::aid-jcp7>3.0.co
Publikováno v:
The Journal of Peptide Research. 54:514-521
We have assigned the disulfide structure of Md-65 agouti-related protein (Md65-AGRP) using differential reduction and alkylation followed by direct sequencing analysis. The mature human AGRP is a single polypeptide chain of 112 amino acid residues, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::841d48cdb6eeaeaf5ae20669eadfb854
https://doi.org/10.1034/j.1399-3011.1999.00126.x
https://doi.org/10.1034/j.1399-3011.1999.00126.x
Autor:
John M. Delaney, Melissa Graham, Andrew A. Welcher, Viswanathan Katta, Kevin Lee Stark, Jamie Baumgartner, Julie Marasco, William Karbon, Clarence Hale, Robert Rosenfeld, Linda O. Narhi, John O. Hui, John S. Philo, Lisa Zeni, Tom Gleason
Publikováno v:
Biochemistry. 37:16041-16052
The agouti-related protein gene (Agrp) is a novel gene implicated in the control of feeding behavior. The hypothalamic expression of Agrp is regulated by leptin, and overexpression of Agrp in transgenic animals results in obesity and diabetes. By ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42bb24573335938302f67f44435d78c
https://doi.org/10.1021/bi981027m
https://doi.org/10.1021/bi981027m
Autor:
Kevin Lee Stark
Publikováno v:
Expert Opinion on Investigational Drugs. 7:859-864
Rapid progress has recently been made to characterise a new pathway involved in the control of feeding behaviour, referred to as the melanocortinergic pathway. Studies of the obese phenotype of the yellow mouse mutant (Ay) suggested the existence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd98e44257e46696fd392d2fd2912ac
https://doi.org/10.1517/13543784.7.6.859
https://doi.org/10.1517/13543784.7.6.859
Publikováno v:
Genes & Development. 11:593-602
We have isolated cDNA clones that encode a novel human gene related to agouti. Sequence analysis of this gene, named ART, for agouti-related transcript, predicts a 132-amino-acid protein that is 25% identical to human agouti. The highest degree of id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263e6fadfe23971e1222d01dcb9965b5
https://doi.org/10.1101/gad.11.5.593
https://doi.org/10.1101/gad.11.5.593
Autor:
Xiaohu Ouyang, Christopher H. Fotsch, Kevin Lee Stark, Mark H. Norman, Bill Karbon, Nuria A. Tamayo, Janet Cheetham, James W. Baumgartner, Martha Zambrano, Michael G. Kelly, Premilla Arasasingham, Clarence Hale
Publikováno v:
Journal of Medicinal Chemistry. 46:9-11
Agouti-related protein (AGRP) is an endogenous antagonist of the melanocortin action.(1) In the hypothalamus, melanocortin peptide agonists act as satiety-inducing factors that mediate their action through the melanocortin-4 receptor (MC4R) whereas A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::297a05d8180b0d7331be2fa82a9dd52e
https://doi.org/10.1021/jm0255522
https://doi.org/10.1021/jm0255522
Autor:
Kevin Lee Stark, Yunjen Young, John O. Hui, David T. Chow, Edward J. Bures, Michael F. Rohde, Lisa Zeni, Mitsuru Haniu, Robert Rosenfeld, Vishwanatham Katta
Publikováno v:
Biochemistry. 37(35)
The agouti-related protein gene (Agrp) plays an important role in body weight regulation. The mature human protein is a single polypeptide chain of 112 amino acid residues, consisting of an N-terminal acidic region and a unique C-terminal cysteine-ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0060e52a1d8668136c35828da2281a2
https://pubmed.ncbi.nlm.nih.gov/9724530
https://pubmed.ncbi.nlm.nih.gov/9724530
Autor:
Dimitry M. Danilenko, Melissa L. Graham, J M Cunningham, V Mar, John R. Shutter, R A Bosselman, J del Castillo, Kevin Lee Stark, Eugene Medlock, I L Ponting, Y Zuo, C P Perkins
Publikováno v:
Genesdevelopment. 11(7)
The mCAT-1 gene encodes a basic amino acid transporter that also acts as the receptor for murine ecotropic leukemia viruses. Targeted mutagenesis in embryonic stem cells has been used to introduce a germ-line null mutation into this gene. This mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1235eae6df2b039ef3a420535049b661
https://pubmed.ncbi.nlm.nih.gov/9106662
https://pubmed.ncbi.nlm.nih.gov/9106662
Publikováno v:
Nature Genetics. 17:273-274
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e1350c8b83f7ae8515ab67aba18f75
https://doi.org/10.1038/ng1197-273
https://doi.org/10.1038/ng1197-273