Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Kevin Lebrigand"'
Autor:
Marin Truchi, Caroline Lacoux, Cyprien Gille, Julien Fassy, Virginie Magnone, Rafael Lopes Goncalves, Cédric Girard-Riboulleau, Iris Manosalva-Pena, Marine Gautier-Isola, Kevin Lebrigand, Pascal Barbry, Salvatore Spicuglia, Georges Vassaux, Roger Rezzonico, Michel Barlaud, Bernard Mari
Publikováno v:
Frontiers in Bioinformatics, Vol 4 (2024)
Single-cell CRISPR-based transcriptome screens are potent genetic tools for concomitantly assessing the expression profiles of cells targeted by a set of guides RNA (gRNA), and inferring target gene functions from the observed perturbations. However,
Externí odkaz:
https://doaj.org/article/961d2c23e9cc4a02a8c14cc9b774b873
Autor:
Benjamin Bian, Agnès Paquet, Marie-Jeanne Arguel, Mickael Meyer, Ludovic Peyre, Asma Chalabi, Marielle Péré, Kevin Lebrigand, Rainer Waldmann, Pascal Barbry, Paul Hofman, Jérémie Roux
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101600- (2022)
Summary: Cell response variability is a starting point in cancer drug resistance that has been difficult to analyze because the tolerant cell states are short lived. Here, we present fate-seq, an approach to isolate single cells in their transient st
Externí odkaz:
https://doaj.org/article/278a66e552af47f4a13fc20d8f42b23a
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Droplet-based high throughput single cell sequencing techniques can often lose information on transcript splicing and heterogenity. Here the authors introduce ScNaUmi-seq, which uses Oxford Nanopore sequencing and barcoding to generate high accuracy
Externí odkaz:
https://doaj.org/article/338e1aedfdba41a0ba4cd63207452b26
Autor:
Clémence Medina, Martine da Rocha, Marc Magliano, Alizée Raptopoulo, Nathalie Marteu, Kevin Lebrigand, Pierre Abad, Bruno Favery, Stéphanie Jaubert-Possamai
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-16 (2018)
Abstract Background Root-knot nematodes (RKN), genus Meloidogyne, are plant parasitic worms that have the ability to transform root vascular cylinder cells into hypertrophied, multinucleate and metabolically over-active feeding cells. Redifferentiati
Externí odkaz:
https://doaj.org/article/f74f06544f66402993d561c1b2dd968d
Autor:
Álvaro Javier Feliz Morel, Anida Hasanovic, Aurélie Morin, Chloé Prunier, Virginie Magnone, Kevin Lebrigand, Amaury Aouad, Sarah Cogoluegnes, Judith Favier, Claude Pasquier, Isabelle Mus-Veteau
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 988 (2022)
Despite the development of new therapeutic strategies, cancer remains one of the leading causes of mortality worldwide. One of the current major challenges is the resistance of cancers to chemotherapy treatments inducing metastases and relapse of the
Externí odkaz:
https://doaj.org/article/80ace4a621564498b21bec9f6d15b51a
Autor:
Béatrice Cambien, Kevin Lebrigand, Alberto Baeri, Nicolas Nottet, Catherine Compin, Audrey Lamit, Olivier Ferraris, Christophe N Peyrefitte, Virginie Magnone, Jérôme Henriques, Laure-Emmanuelle Zaragosi, Sophie Giorgetti-Peraldi, Frédéric Bost, Marine Gautier-Isola, Roger Rezzonico, Pascal Barbry, Robert Barthel, Bernard Mari, Georges Vassaux
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008660 (2020)
Mammary carcinoma, including triple-negative breast carcinomas (TNBC) are tumor-types for which human and canine pathologies are closely related at the molecular level. The efficacy of an oncolytic vaccinia virus (VV) was compared in low-passage prim
Externí odkaz:
https://doaj.org/article/198a1a51898d44c0979a58f01abe50b5
Autor:
Nicole Arrighi, Claudine Moratal, Grégoire Savary, Julien Fassy, Nicolas Nottet, Nicolas Pons, Noémie Clément, Sandy Fellah, Romain Larrue, Virginie Magnone, Kevin Lebrigand, Nicolas Pottier, Claude Dechesne, Georges Vassaux, Christian Dani, Pascal Peraldi, Bernard Mari
Publikováno v:
Cells, Vol 10, Iss 7, p 1832 (2021)
Fibrosis is a deleterious invasion of tissues associated with many pathological conditions, such as Duchenne muscular dystrophy (DMD) for which no cure is at present available for its prevention or its treatment. Fibro-adipogenic progenitors (FAPs) a
Externí odkaz:
https://doaj.org/article/cdb7303874f544cd8594f9bec4dc253f
Autor:
Ilaria Bassani, Corinne Rancurel, Sophie Pagnotta, François Orange, Nicolas Pons, Kevin Lebrigand, Franck Panabières, Laurent Counillon, Xavier Noblin, Eric Galiana
Publikováno v:
Microorganisms, Vol 8, Iss 7, p 1012 (2020)
Most pathogenic oomycetes of the genus Phytophthora spread in water films as flagellated zoospores. Zoospores perceive and produce signals attracting other zoospores, resulting in autoaggregation in vitro or biofilm formation on plant surface. The me
Externí odkaz:
https://doaj.org/article/53f581f0e661459583e5471b9c6b5cf2
Autor:
Hadi Zarif, Salma Hosseiny, Agnès Paquet, Kevin Lebrigand, Marie-Jeanne Arguel, Julie Cazareth, Anne Lazzari, Catherine Heurteaux, Nicolas Glaichenhaus, Joëlle Chabry, Alice Guyon, Agnès Petit-Paitel
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 10 (2018)
Living in an enriched environment (EE) benefits health by acting synergistically on various biological systems including the immune and the central nervous systems. The dialog between the brain and the immune cells has recently gained interest and is
Externí odkaz:
https://doaj.org/article/72ce781340c74c69b4af11b97330b404
Autor:
Ludovic Pruneau, Kevin Lebrigand, Bernard Mari, Thierry Lefrançois, Damien F. Meyer, Nathalie Vachiery
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
The obligate intracellular pathogenic bacterium, Ehrlichia ruminantium, is the causal agent of heartwater, a fatal disease in ruminants transmitted by Amblyomma ticks. So far, three strains have been attenuated by successive passages in mammalian cel
Externí odkaz:
https://doaj.org/article/8f2f7c6509504be6b8a21f8a80e01752