Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Kevin Laliberte"'
Autor:
Franz Rischard, Kevin Laliberte, Jeremy Feldman, Murali M. Chakinala, Meredith Broderick, Nicole Leedom, R. James White, Michael A. Mathier
Publikováno v:
The Journal of Heart and Lung Transplantation. 36:193-201
BackgroundParenteral prostanoids are effective treatment for pulmonary arterial hypertension, but long-term pump infusion systems have significant delivery-related safety and convenience limitations.MethodsSubjects with a favorable risk profile trans
Autor:
Stanford L. Peng, Kristan D. Rollins, Robert Spiera, Robert W. Simms, Dinesh Khanna, John Varga, Virginia D. Steen, Maureen D. Mayes, Fredrick M. Wigley, Naomi F. Rothfield, Barri J. Fessler, Bashar Kahaleh, Lorinda Chung, Richard M. Silver, David H. Collier, Elena Schiopu, Robyn T. Domsic, Soumya Chatterjee, Michael Wade, Christopher P. Denton, Murray Baron, Kevin Laliberte, Jerry A. Molitor, Mary Ellen Csuka, Vivien Hsu, Thomas A. Medsger, James R. Seibold, Ariane L. Herrick, Tracy M. Frech, Janet E. Pop
Publikováno v:
Journal of Scleroderma and Related Disorders. 2:42-49
Background Prostacyclins are routinely used to treat vascular features of systemic sclerosis (SSc, scleroderma) but require parenteral infusion or inhalation. This study evaluated the safety and efficacy of oral treprostinil in digital ulcers seconda
Publikováno v:
Journal of Cardiovascular Pharmacology. 63:227-232
Background Treprostinil diolamine (oral treprostinil) is an orally available prostacyclin analog that was developed for the treatment of pulmonary arterial hypertension. This study aimed to evaluate the pharmacokinetics (PK), safety, and tolerability
Autor:
Victor F. Tapson, Zhi-Cheng Jing, Kai-Feng Xu, Lei Pan, Jeremy Feldman, David G. Kiely, Eugene Kotlyar, C. Shane McSwain, Kevin Laliberte, Carl Arneson, Lewis J. Rubin
Publikováno v:
Chest. 144:952-958
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics. 38:518-523
Summary What is known and objective Treprostinil diolamine (oral treprostinil) is a prostacyclin analogue under evaluation for the treatment for pulmonary arterial hypertension (PAH). This study assessed the pharmacokinetics (PK) and safety of trepro
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics. 38:450-455
Summary What is known Treprostinil diolamine (oral treprostinil) is a prostacyclin analogue currently being evaluated for the treatment of pulmonary arterial hypertension as a sustained-release (SR) oral tablet. Previous data have demonstrated that t
Autor:
Jean Francois Marier, Victor F. Tapson, Kevin Laliberte, Carlos Jerjes, Tomás Pulido, David Yehle, Fernando Torres, Meredith Howell, R. James White, Roblee P Allen
Publikováno v:
Journal of Cardiovascular Pharmacology. 61:474-481
Pulmonary arterial hypertension (PAH) is a progressive vascular disease that ultimately leads to right ventricular failure and death. Treprostinil diolamine is an oral prostacyclin analogue; sustained release tablets of oral treprostinil are currentl
Publikováno v:
Journal of Cardiovascular Pharmacology. 61:444-451
Treprostinil, a stable prostacyclin analogue used in the treatment of pulmonary arterial hypertension, is in development as a sustained release oral tablet, treprostinil diolamine (United Therapeutics Corp, Research Triangle Park, NC). As combination
Autor:
Shelley M. Shapiro, Victor F. Tapson, Kevin Laliberte, Roblee P Allen, Robert P. Frantz, Anne Keogh, Carl Arneson, Fernando Torres, Jeffrey Sigman, David B. Badesch, Adaani E. Frost, Fiona Kermeen, Nazzareno Galiè
Publikováno v:
Chest. 142:1383-1390
Background Treprostinil is a stable prostacyclin analog approved for the treatment of pulmonary arterial hypertension (PAH) as parenteral or inhaled therapy. Treprostinil diolamine, a sustained-release oral formulation of treprostinil, was studied to
Publikováno v:
The Journal of Vascular Access. 6:177-181
Purpose Two animal studies were conducted to determine the feasibility of infusing treprostinil via a central venous catheter at an infusion rate of 0.1 mL/hour. Currently treprostinil is administered intravenously at infusion rates of approximately