Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Kevin L Duffin"'
Autor:
Kim Henriksen, Yaguo Wang, Mette G Sørensen, Natasha Barascuk, Joyce Suhy, Jan T Pedersen, Kevin L Duffin, Robert A Dean, Monika Pajak, Claus Christiansen, Qinlong Zheng, Morten A Karsdal
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64990 (2013)
ObjectiveAlzheimer's disease (AD) is a devastating neurological disease characterized by pathological proteolytic cleavage of tau protein, which appears to initiate death of the neurons. The objective of this study was to investigate whether a proteo
Externí odkaz:
https://doaj.org/article/2b6f9215175d48329c9c1c6a33b5e397
Autor:
Michael Kammer, Andreas Heinzel, Karin Hu, Heike Meiselbach, Mariella Gregorich, Martin Busch, Kevin L. Duffin, Maria F. Gomez, Kai-Uwe Eckardt, Rainer Oberbauer, for the BEAt-DKD consortium
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-10 (2023)
Abstract Background Chronic kidney disease (CKD) is a common comorbidity in people with diabetes mellitus, and a key risk factor for further life-threatening conditions such as cardiovascular disease. The early prediction of progression of CKD theref
Externí odkaz:
https://doaj.org/article/e1be205a485743f2afe079c7e9c5230b
Autor:
Hiddo J.L. Heerspink, Naveed Sattar, Imre Pavo, Axel Haupt, Kevin L. Duffin, Zhengyu Yang, Russell John Wiese, Katherine R. Tuttle, David Z.I. Cherney, Jochen Seufert
Publikováno v:
Diabetologie und Stoffwechsel.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c1be4acd39e077d74ed3ceeabd7e119
https://doi.org/10.1055/s-0043-1767986
https://doi.org/10.1055/s-0043-1767986
Autor:
Hertzel C. Gerstein, Shun-Fu Lee, Guillaume Paré, M. Angelyn Bethel, Helen M. Colhoun, Anastasia Hoover, Mark Lakshmanan, Yanzhu Lin, Valentino Pirro, Hui-Rong Qian, Giacomo Ruotolo, Lars Ryden, Jonathan M. Wilson, Kevin L. Duffin
OBJECTIVE The glucagon-like peptide-1 receptor agonist dulaglutide reduced MACE in the Researching Cardiovascular Events with a Weekly Incretin in Diabetes (REWIND) trial. This article expores the relationship of selected biomarkers to both dulagluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2640ca757c8cf50993017da4bd7b9737
https://doi.org/10.2337/figshare.22120097
https://doi.org/10.2337/figshare.22120097
Autor:
Hiroki Kobayashi, Helen C. Looker, Eiichiro Satake, Francesca D’Addio, Jonathan M. Wilson, Pierre Jean Saulnier, Zaipul I. Md Dom, Kristina O’Neil, Katsuhito Ihara, Bozena Krolewski, Hannah S. Badger, Adriana Petrazzuolo, Domenico Corradi, Andrzej Galecki, Parker C. Wilson, Behzad Najafian, Michael Mauer, Monika A. Niewczas, Alessandro Doria, Benjamin D. Humphreys, Kevin L. Duffin, Paolo Fiorina, Robert G. Nelson, Andrzej S. Krolewski
Publikováno v:
Sci Transl Med
Circulating proteins associated with transforming growth factor-β (TGF-β) signaling are implicated in the development of diabetic kidney disease (DKD). No study has comprehensively examined which of these proteins are involved in the pathogenesis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0ce2222672f29b59c3bc4fbd3fc7550
https://pubmed.ncbi.nlm.nih.gov/35947673
https://pubmed.ncbi.nlm.nih.gov/35947673
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Growth/differentiation factor-15 (GDF-15) is a distant member of the transforming growth factor β (TGF-β) superfamily and is widely expressed in multiple mammalian tissues. Its expression is highly regulated and is often induced in response to cond
Externí odkaz:
https://doaj.org/article/e62acf91ab594e15a9557fc257b53462
Autor:
Kenneth D. Roth, Valentina Pirro, Kevin L. Duffin, Jonathan M. Wilson, Yanzhu Lin, Jill A. Willency, Axel Haupt, Paul L. Milligan, Christopher B. Newgard, Giacomo Ruotolo
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 107:363-378
Context Tirzepatide substantially reduced hemoglobin A1c (HbA1c) and body weight in subjects with type 2 diabetes (T2D) compared with the glucagon-like peptide 1 receptor agonist dulaglutide. Improved glycemic control was associated with lower circul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3140a92fd3671aef505b0ff756594a2c
https://doi.org/10.1210/clinem/dgab722
https://doi.org/10.1210/clinem/dgab722
Autor:
Caterina Pipino, Andrzej S. Krolewski, C. Ronald Kahn, Meda E. Pavkov, Helen C. Looker, Bozena Krolewski, Behzad Najafian, Rohit N. Kulkarni, Michael Mauer, Zaipul I. Md Dom, Marcus G. Pezzolesi, Pierre-Jean Saulnier, Viji Nair, Matthias Kretzler, Monika A. Niewczas, Eiichiro Satake, Robert G. Nelson, Manoj K. Gupta, Hiroki Kobayashi, Alessandro Doria, Kristina O’Neil, Kevin L. Duffin, Jonathan M. Wilson, Markus Bitzer, Katsuhito Ihara
Publikováno v:
J Am Soc Nephrol
BACKGROUND: Mechanisms underlying the pro gression of diabetic kidney disease to ESKD are not fully understood. METHODS: We performed global microRNA (miRNA) analysis on plasma from two cohorts consisting of 375 individuals with type 1 and type 2 dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26743561cbc88e3c5896747d85c25e2c
https://doi.org/10.1681/asn.2021010105
https://doi.org/10.1681/asn.2021010105
Autor:
Hiddo J L, Heerspink, Naveed, Sattar, Imre, Pavo, Axel, Haupt, Kevin L, Duffin, Zhengyu, Yang, Russell J, Wiese, Katherine R, Tuttle, David Z I, Cherney
Publikováno v:
The Lancet Diabetes and Endocrinology, 10(11), 774-785. ELSEVIER SCIENCE INC
Background: In the SURPASS-4 trial, the dual GIP and GLP-1 receptor agonist tirzepatide reduced HbA1c concentrations, bodyweight, and blood pressure more than titrated daily insulin glargine in people with type 2 diabetes inadequately controlled on o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e32ba5e7ec793343b56a3763241de9
https://research.rug.nl/en/publications/9fd182d5-8590-4916-a1a3-8301509299bf
https://research.rug.nl/en/publications/9fd182d5-8590-4916-a1a3-8301509299bf
Autor:
Guanlin Li, Grace Lai-Hung Wong, Terry Cheuk-Fung Yip, Qingxiong Tan, Huapeng Lin, Jonathan Matthew Wilson, Lenden M Bowsman, Joseph V Haas, Anthony Wing-Hung Chan, Howard Ho-Wai Leung, Xinrong Zhang, Yee-Kit Tse, Sally She-Ting Shu, Angel Mei-Ling Chim, Henry Lik-Yuen Chan, Pong Chi Yuen, Vincent Wai-Sun Wong, Kevin L. Duffin, Yu Chen
Background: A number of protein biomarkers have been proposed for the assessment of non-alcoholic fatty liver disease (NAFLD), but few have been externally validated and directly compared. The aim of this study was to compare the diagnostic accuracie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd9b3fef1e7201d42071066eede5d386
https://doi.org/10.21203/rs.3.rs-2118271/v1
https://doi.org/10.21203/rs.3.rs-2118271/v1