Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Kevin L Briggman"'
Autor:
Anja Günther, Silke Haverkamp, Stephan Irsen, Paul V. Watkins, Karin Dedek, Henrik Mouritsen, Kevin L. Briggman
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract In most avian retinas, double cones (consisting of a principal and accessory member) outnumber other photoreceptor types and have been associated with various functions, such as encoding luminance, sensing polarized light, and magnetorecepti
Externí odkaz:
https://doaj.org/article/4445fcba464f4782ac7b897989e1c394
Autor:
Lennart Tegethoff, Kevin L. Briggman
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Optimal epoxy resin embedding is crucial for obtaining consistent serial sections from large tissue samples, especially for block faces spanning >1 mm2. We report a method to quantify non-uniformity in resin curing using block hardness measurements f
Externí odkaz:
https://doaj.org/article/6df12df9307641558c4103eb57487767
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Serial section multibeam scanning electron microscopy (ssmSEM) is currently among the fastest technologies available for acquiring 3D anatomical data spanning relatively large neural tissue volumes, on the order of 1 mm3 or larger, at a resolution su
Externí odkaz:
https://doaj.org/article/28979740c93a48cb83eed7d9a55aa80d
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2022)
Although retinal organization is remarkably conserved, morphological anomalies can be found to different extents and varieties across animal species with each presenting unique characteristics and patterns of displaced and misplaced neurons. One of t
Externí odkaz:
https://doaj.org/article/89af0a1ac3c640d1944e022549b32203
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The mechanisms of contextual modulation in direction selective ganglion cells in the retina remain unclear. Here, the authors find that that On-Off direction-selective ganglion cells are differentially sensitive to discontinuities of dark and bright
Externí odkaz:
https://doaj.org/article/d88967dd20f44d26bf598cccde811666
Autor:
Kara A Fulton, Kevin L Briggman
Publikováno v:
eLife, Vol 10 (2021)
A dense reconstruction of neuronal synaptic connectivity typically requires high-resolution 3D electron microscopy (EM) data, but EM data alone lacks functional information about neurons and synapses. One approach to augment structural EM datasets is
Externí odkaz:
https://doaj.org/article/ff6cadc4394c4ed78b5e53f58b064555
Autor:
Silvia JH Park, Evan E Lieberman, Jiang-Bin Ke, Nao Rho, Padideh Ghorbani, Pouyan Rahmani, Na Young Jun, Hae-Lim Lee, In-Jung Kim, Kevin L Briggman, Jonathan B Demb, Joshua H Singer
Publikováno v:
eLife, Vol 9 (2020)
Night vision in mammals depends fundamentally on rod photoreceptors and the well-studied rod bipolar (RB) cell pathway. The central neuron in this pathway, the AII amacrine cell (AC), exhibits a spatially tuned receptive field, composed of an excitat
Externí odkaz:
https://doaj.org/article/1a1dcc80608b452db3fc0bfe5ad86051
Publikováno v:
PLoS Biology, Vol 17, Iss 10, p e3000480 (2019)
Many species execute ballistic escape reactions to avoid imminent danger. Despite fast reaction times, responses are often highly regulated, reflecting a trade-off between costly motor actions and perceived threat level. However, how sensory cues are
Externí odkaz:
https://doaj.org/article/449171896f264041a0db80ba58537448
Autor:
Shai Sabbah, Carin Papendorp, Inbar Behrendt, Hala Rasras, Jesse Cann, Megan L. Leyrer, Elizabeth Koplas, Marjo Beltoja, Cameron Etebari, Ali Noel Gunesch, Luis Carrete, Min Tae Kim, Gabrielle Manoff, Ananya Bhatia-Lin, Tiffany Zhao, Henry Dowling, Kevin L. Briggman, David M. Berson
Publikováno v:
SSRN Electronic Journal.
SummaryThe retina encodes environmental light intensity to drive innate physiological responses. The synaptic basis of such coding remains obscure. Intrinsically photosensitive retinal ganglion cells (ipRGCs) are the only retinal output neurons stabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1919a6d29308d059361b274198c08b0
https://doi.org/10.2139/ssrn.4081521
https://doi.org/10.2139/ssrn.4081521
Publikováno v:
eLife, Vol 4 (2015)
Dense connectomic mapping of neuronal circuits is limited by the time and effort required to analyze 3D electron microscopy (EM) datasets. Algorithms designed to automate image segmentation suffer from substantial error rates and require significant
Externí odkaz:
https://doaj.org/article/0088c1359cb84b7394cbe6c221052f75