Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Kevin L Bennewith"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Oral squamous cell carcinoma (OSCC) is the most common form of head and neck cancer and has a survival rate of ∼50% over 5 years. New treatment strategies are sorely needed to improve survival rates—and a better understanding of the
Externí odkaz:
https://doaj.org/article/39b40ddacc8945859dd659e02742106c
Autor:
Lisa R. Decotret, Rocky Shi, Kiersten N. Thomas, Manchi Hsu, Catherine J. Pallen, Kevin L. Bennewith
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Organotypic cultures of murine brain slices are well-established tools in neuroscience research, including electrophysiology studies, modeling neurodegeneration, and cancer research. Here, we present an optimized ex vivo brain slice invasion assay th
Externí odkaz:
https://doaj.org/article/8df087dba80a434fb6e21bfef215d29d
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2022 (2023)
Immunotherapy has changed the way many cancers are being treated. Researchers in the field of immunotherapy and tumor immunology are investigating similar questions: How can the positive benefits achieved with immunotherapies be enhanced? Can this be
Externí odkaz:
https://doaj.org/article/eb99b9eb33a04b9c94d4b5bce8a95c81
Autor:
Rachel A. Cederberg, Sarah Elizabeth Franks, Brennan J. Wadsworth, Alvina So, Lisa R. Decotret, Michael G. Hall, Rocky Shi, Michael R. Hughes, Kelly M. McNagny, Kevin L. Bennewith
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Metastatic breast cancer is challenging to effectively treat, highlighting the need for an improved understanding of host factors that influence metastatic tumor cell colonization and growth in distant tissues. The lungs are a common site of breast c
Externí odkaz:
https://doaj.org/article/cdcf48cc602a4a0791bfc7101a827e71
Autor:
Chandra Lebovitz, Nicole Wretham, Maryam Osooly, Katy Milne, Tia Dash, Shelby Thornton, Basile Tessier-Cloutier, Paalini Sathiyaseelan, Svetlana Bortnik, Nancy Erro Go, Elizabeth Halvorsen, Rachel A. Cederberg, Norman Chow, Nancy Dos Santos, Kevin L. Bennewith, Brad H. Nelson, Marcel B. Bally, Wan L. Lam, Sharon M. Gorski
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Pathological links between neurodegenerative disease and cancer are emerging. LRRK2 overactivity contributes to Parkinson’s disease, whereas our previous analyses of public cancer patient data revealed that decreased LRRK2 expression is as
Externí odkaz:
https://doaj.org/article/a628231eefc547ca89a67c8ce3fcdf31
Autor:
Etienne S. Melese, Elizabeth Franks, Rachel A. Cederberg, Bryant T. Harbourne, Rocky Shi, Brennan J. Wadsworth, Jenna L. Collier, Elizabeth C. Halvorsen, Fraser Johnson, Jennifer Luu, Min Hee Oh, Vivian Lam, Gerald Krystal, Shelley B. Hoover, Mark Raffeld, R. Mark Simpson, Arun M. Unni, Wan L. Lam, Stephen Lam, Ninan Abraham, Kevin L. Bennewith, William W. Lockwood
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Current immunotherapies for lung cancer are only effective in a subset of patients. Identifying tumor-derived factors that facilitate immunosuppression offers the opportunity to develop novel strategies to supplement and improve current therapeutics.
Externí odkaz:
https://doaj.org/article/2c2a00203bef4e89885342925d64134f
Autor:
Momir Bosiljcic, Rachel A. Cederberg, Melisa J. Hamilton, Nancy E. LePard, Bryant T. Harbourne, Jenna L. Collier, Elizabeth C. Halvorsen, Rocky Shi, S. Elizabeth Franks, Ada Y. Kim, Judit P. Banáth, Mark Hamer, Fabio M. Rossi, Kevin L. Bennewith
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-16 (2019)
Abstract Background Solid tumors produce proteins that can induce the accumulation of bone marrow-derived cells in various tissues, and these cells can enhance metastatic tumor growth by several mechanisms. 4T1 murine mammary tumors are known to prod
Externí odkaz:
https://doaj.org/article/27a7a3ac6dc84010a63536a5241f3077
Autor:
Natalie S Firmino, Rachel A Cederberg, Che-Min Lee, Rocky Shi, Brennan J Wadsworth, S Elizabeth Franks, Kiersten N Thomas, Lisa R Decotret, Kevin L Bennewith
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Hypoxia develops in germinal centers (GCs) induced by model antigens; however, it is unknown whether tumor-reactive GCs are also hypoxic. We identified GC hypoxia in lymph nodes (LNs) draining murine mammary tumors and lethally irradiated tumor cells
Externí odkaz:
https://doaj.org/article/564080d65da14b9aa13ca29d3b8f43bd
Publikováno v:
Annual Review of Analytical Chemistry. 15:221-246
Oxygen plays a fundamental role in respiration and metabolism, and quantifying oxygen levels is essential in many environmental, industrial, and research settings. Microdevices facilitate the study of dynamic, oxygen-dependent effects in real time. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ed4c20e3c7255c0cc1a5e1befbfde1
https://doi.org/10.1146/annurev-anchem-061020-111458
https://doi.org/10.1146/annurev-anchem-061020-111458
Autor:
Nicholas C. Denko, Daniel T. Chang, Amato J. Giaccia, Edward E. Graves, Kevin L. Bennewith, Rob A. Cairns
Supplementary Data from Pharmacologically Increased Tumor Hypoxia Can Be Measured by 18F-Fluoroazomycin Arabinoside Positron Emission Tomography and Enhances Tumor Response to Hypoxic Cytotoxin PR-104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff9c571e4c6f1fd6dbbcbe7bc4b52c9
https://doi.org/10.1158/1078-0432.22440321
https://doi.org/10.1158/1078-0432.22440321
