Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kevin Lüthy"'
Autor:
Martin Helmstädter, Kevin Lüthy, Markus Gödel, Matias Simons, Ashish, Deepak Nihalani, Stefan A Rensing, Karl-Friedrich Fischbach, Tobias B Huber
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40300 (2012)
Neph molecules are highly conserved immunoglobulin superfamily proteins (IgSF) which are essential for multiple morphogenetic processes, including glomerular development in mammals and neuronal as well as nephrocyte development in D. melanogaster. Wh
Externí odkaz:
https://doaj.org/article/c9bc8bbf71a24f9582410edccb150a54
Autor:
Paul Lasko, Kevin Lüthy
Publikováno v:
Faculty Reviews, 10, 1-9
Faculty Reviews
Faculty Reviews, 10, 10, pp. 1-9
Faculty Reviews
Faculty Reviews, 10, 10, pp. 1-9
One in three epilepsy cases is drug resistant, and seizures often begin in infancy, when they are life-threatening and when therapeutic options are highly limited. An important tool for prioritizing and validating genes associated with epileptic cond
Autor:
Baptiste Fischer, Inge A. Meijer, Renzo Guerrini, Naomi Lubarr, Paolo Aridon, Nils Schoovaerts, Maurizio De Fusco, Elena Parrini, Jef Swerts, Giorgio Casari, Patrik Verstreken, Katherine M. Mackenzie, Wim Versées, Wang-Tso Lee, Jone Paesmans, Davide Cittaro, Davide Mei, Kevin Lüthy
Publikováno v:
Brain
Genetic mutations in TBC1D24 have been associated with multiple phenotypes, with epilepsy being the main clinical manifestation. The TBC1D24 protein consists of the unique association of a Tre2/Bub2/Cdc16 (TBC) domain and a TBC/lysin motif domain/cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652286af42bf1dc5ebe84c1211b0f53f
Autor:
Karl-Friedrich Fischbach, Shilpa Rawal, Kevin Lüthy, Zhiyuan Lu, Dorota Tarnogorska, Ian A. Meinertzhagen, Birgit Ahrens
Publikováno v:
Journal of Neurogenetics. 28:291-301
Each neuropil module, or cartridge, in the fly's lamina has a fixed complement of cells. Of five types of monopolar cell interneurons, only L4 has collaterals that invade neighboring cartridges. In the proximal lamina, these collaterals form reciproc
Autor:
Stefan Feske, Claire Hivroz, Gideon Rechavi, Anjana Rao, Capucine Picard, Alexander Papolos, Francoise LeDeist, Frédéric Rieux-Laucat, Kevin Lüthy, Alain Fischer, Christie Ann McCarl, Sara Khalil
Publikováno v:
New England Journal of Medicine. 360:1971-1980
A mutation in ORAI1, the gene encoding the pore-forming subunit of the Ca(2+)-release-activated Ca(2+) (CRAC) channel, abrogates the store-operated entry of Ca(2+) into cells and impairs lymphocyte activation. Stromal interaction molecule 1 (STIM1) i
T cell function is dependent on store-operated Ca2+ influx that is activated by the stromal interaction molecules (STIM) 1 and 2. We show that mice with T-cell specific deletion of STIM1 or STIM2 are protected from experimental autoimmune encephalomy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d05faffbd418a207ffba7b289c7c1a
https://europepmc.org/articles/PMC3517124/
https://europepmc.org/articles/PMC3517124/
Autor:
Jone Paesmans, Valerie Uytterhoeven, Jef Swerts, Baptiste Fischer, Ine Maes, Kevin Lüthy, Wim Versées, Sabine Kuenen, Charlotte De Koninck, Patrik Verstreken
Publikováno v:
Nature Structural & Molecular Biology
Mutations in TBC1D24 cause severe epilepsy and DOORS syndrome, but the molecular mechanisms underlying these pathologies are unresolved. We solved the crystal structure of the TBC domain of the Drosophila ortholog Skywalker, revealing an unanticipate
Publikováno v:
Vrije Universiteit Brussel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1793581281621687c498f464ccbf14a3
https://cris.vub.be/en/publications/compounds-for-treatment-of-intractable-epilepsy-and-doors-syndrome(e12a165b-5789-46b5-927b-e6eb4249f9a8).html
https://cris.vub.be/en/publications/compounds-for-treatment-of-intractable-epilepsy-and-doors-syndrome(e12a165b-5789-46b5-927b-e6eb4249f9a8).html
Autor:
Jone Paesmans, Baptiste Fischer, Kevin Lüthy, Charlotte De Koninck, Maes, I., Swerts, J., Kuenen, S., Uytterhoeven, V., Patrik Verstreken, Wim Versées
Publikováno v:
Vrije Universiteit Brussel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::aabc8d8eef806d78c78c469d9a52378b
https://researchportal.vub.be/en/publications/3deceab7-08f3-45e4-92a1-7df5d42e35a1
https://researchportal.vub.be/en/publications/3deceab7-08f3-45e4-92a1-7df5d42e35a1