Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Kevin L, Grove"'
Autor:
Eunsang Hwang, Jarrad M. Scarlett, Arian F. Baquero, Camdin M. Bennett, Yanbin Dong, Dominic Chau, Jenny M. Brown, Aaron J. Mercer, Thomas H. Meek, Kevin L. Grove, Bao Anh N. Phan, Gregory J. Morton, Kevin W. Williams, Michael W. Schwartz
Publikováno v:
JCI Insight, Vol 7, Iss 17 (2022)
In rodent models of type 2 diabetes (T2D), central administration of FGF1 normalizes elevated blood glucose levels in a manner that is sustained for weeks or months. Increased activity of NPY/AgRP neurons in the hypothalamic arcuate nucleus (ARC) is
Externí odkaz:
https://doaj.org/article/df6556bb07904915ad6da9a771a2e516
Autor:
Marie A. Bentsen, Dylan M. Rausch, Zaman Mirzadeh, Kenjiro Muta, Jarrad M. Scarlett, Jenny M. Brown, Vicente Herranz-Pérez, Arian F. Baquero, Jonatan Thompson, Kimberly M. Alonge, Chelsea L. Faber, Karl J. Kaiyala, Camdin Bennett, Charles Pyke, Cecilia Ratner, Kristoffer L. Egerod, Birgitte Holst, Thomas H. Meek, Burak Kutlu, Yu Zhang, Thomas Sparso, Kevin L. Grove, Gregory J. Morton, Birgitte R. Kornum, José-Manuel García-Verdugo, Anna Secher, Rasmus Jorgensen, Michael W. Schwartz, Tune H. Pers
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
In rodent models of type 2 diabetes, sustained remission of hyperglycemia can be induced by FGF1 action in the mediobasal hypothalamus. Here, the authors show that FGF1-injection is followed by marked changes in glial cell populations and that the su
Externí odkaz:
https://doaj.org/article/3be801c6633040a49c4814f636359746
Autor:
Brandon L. Roberts, Baylin J. Bennett, Camdin M. Bennett, Julie M. Carroll, Louise S. Dalbøge, Colin Hall, Wafa Hassouneh, Kristy M. Heppner, Melissa A. Kirigiti, Sarah R. Lindsley, Katherine G. Tennant, Cadence A. True, Andrew Whittle, Anitra C. Wolf, Charles T. Roberts, Jr., Mads Tang-Christensen, Mark W. Sleeman, Michael A. Cowley, Kevin L. Grove, Paul Kievit
Publikováno v:
Molecular Metabolism, Vol 26, Iss , Pp 18-29 (2019)
Objective: Reelin (RELN) is a large glycoprotein involved in synapse maturation and neuronal organization throughout development. Deficits in RELN signaling contribute to multiple psychological disorders, such as autism spectrum disorder, schizophren
Externí odkaz:
https://doaj.org/article/2fb89f157ba64298a2342ca376aaca21
Autor:
Pablo J. Enriori, Weiyi Chen, Maria C. Garcia-Rudaz, Bernadette E. Grayson, Anne E. Evans, Sarah M. Comstock, Ursel Gebhardt, Hermann L. Müller, Thomas Reinehr, Belinda A. Henry, Russell D. Brown, Clinton R. Bruce, Stephanie E. Simonds, Sara A. Litwak, Sean L. McGee, Serge Luquet, Sarah Martinez, Martin Jastroch, Matthias H. Tschöp, Matthew J. Watt, Iain J. Clarke, Christian L. Roth, Kevin L. Grove, Michael A. Cowley
Publikováno v:
Molecular Metabolism, Vol 5, Iss 10, Pp 807-822 (2016)
Objective: Central melanocortin pathways are well-established regulators of energy balance. However, scant data exist about the role of systemic melanocortin peptides. We set out to determine if peripheral α-melanocyte stimulating hormone (α-MSH) p
Externí odkaz:
https://doaj.org/article/6eebea40ad004d3084746b4f5118b1a3
Publikováno v:
Molecular Metabolism, Vol 5, Iss 3, Pp 198-209 (2016)
Objective: Humans and animals exposed to undernutrition (UN) during development often experience accelerated “catch-up” growth when food supplies are plentiful. Little is known about the mechanisms regulating early growth rates. We previously rep
Externí odkaz:
https://doaj.org/article/dbcd927f74134d3e8720fa3bc68cb834
Autor:
Yosuke Tanigawa, Jiekun Yang, Päivi Pajukanta, Maria Vamvini, Laurie J. Goodyear, Manolis Kellis, Roeland J.W. Middelbeek, Kiki Galani, Leandro Z. Agudelo, Markku Laakso, Kevin L. Grove, Pasquale Nigro, Li-Lun Ho, Marcus Alvarez
Regular physical exercise has long been recognized to reverse the effects of diet-induced obesity, but the molecular mechanisms mediating these multi-tissue beneficial effects remain uncharacterized. Here, we address this challenge by studying the op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fa52d28e5e2106a254fa43d5c414dfc
https://doi.org/10.1101/2021.11.22.469622
https://doi.org/10.1101/2021.11.22.469622
Autor:
Leandro Z. Agudelo, Teresa Femenía, Suvi Linna-Kuosmanen, Na Sun, Claudia Llinares, Yongjin Park, Burak Kutlu, Kevin L. Grove, Li Lun Ho, Manolis Kellis, Naeimeh Atabaki-Pasdar, Rémy Tuyéras, Galani K, Alvaro Morcuende, Paul W. Franks
Metabolism plays a central role in evolution, as resource conservation is a selective pressure for fitness and survival. Resource-driven adaptations offer a good model to study evolutionary innovation more broadly. It remains unknown how resource-dri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f599e82e3d8aaff5946818b645d910c9
https://doi.org/10.21203/rs.3.rs-716965/v1
https://doi.org/10.21203/rs.3.rs-716965/v1
Autor:
Katherine G. Tennant, Camdin M. Bennett, Kevin L. Grove, Kristy M. Heppner, Paul Kievit, Baylin J. Bennett, Charles T. Roberts, Wafa Hassouneh, Julie M. Carroll, Mads Tang-Christensen, Andrew J. Whittle, Mark W. Sleeman, Cadence True, Michael A. Cowley, Brandon L. Roberts, Anitra C. Wolf, Louise S. Dalbøge, Melissa A. Kirigiti, Sarah R. Lindsley, Colin Hall
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 26, Iss, Pp 18-29 (2019)
Molecular Metabolism, Vol 26, Iss, Pp 18-29 (2019)
Objective Reelin (RELN) is a large glycoprotein involved in synapse maturation and neuronal organization throughout development. Deficits in RELN signaling contribute to multiple psychological disorders, such as autism spectrum disorder, schizophreni
Autor:
Jacob Sten Petersen, Gustaf Christoffersson, Mads Tang-Christensen, Allan E. Karlsen, Kevin L. Grove, Philippe P. Pagni, Matthias von Herrath
Publikováno v:
Cell Metabolism. 29:795-802
Recent articles have highlighted the lack of reproducibility of data from scientific publications. Here we would argue that a better way to describe and also tackle this matter is to use the term "lack of robustness," since it points toward potential
Autor:
Jenny M. Brown, Arian F. Baquero, Erin J. Whalen, Gregory J. Morton, Aaron J. Mercer, Casper Gravesen Salinas, Jarrad M. Scarlett, Frank H. Koegler, Anda Cornea, Karin Hultman, Kevin L. Grove, Michael W. Schwartz, Yu Zhang
Publikováno v:
Journal of Comparative Neurology. 527:2069-2085
Central activation of fibroblast growth factor (FGF) receptors regulates peripheral glucose homeostasis and reduces food intake in preclinical models of obesity and diabetes. The current work was undertaken to advance our understanding of the recepto