Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Kevin L, Duffin"'
Autor:
Michael Kammer, Andreas Heinzel, Karin Hu, Heike Meiselbach, Mariella Gregorich, Martin Busch, Kevin L. Duffin, Maria F. Gomez, Kai-Uwe Eckardt, Rainer Oberbauer, for the BEAt-DKD consortium
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-10 (2023)
Abstract Background Chronic kidney disease (CKD) is a common comorbidity in people with diabetes mellitus, and a key risk factor for further life-threatening conditions such as cardiovascular disease. The early prediction of progression of CKD theref
Externí odkaz:
https://doaj.org/article/e1be205a485743f2afe079c7e9c5230b
Autor:
Chuanyan Wu, Yan Borné, Rui Gao, Maykel López Rodriguez, William C. Roell, Jonathan M. Wilson, Ajit Regmi, Cheng Luan, Dina Mansour Aly, Andreas Peter, Jürgen Machann, Harald Staiger, Andreas Fritsche, Andreas L. Birkenfeld, Rongya Tao, Robert Wagner, Mickaël Canouil, Mun-Gwan Hong, Jochen M. Schwenk, Emma Ahlqvist, Minna U. Kaikkonen, Peter Nilsson, Angela C. Shore, Faisel Khan, Andrea Natali, Olle Melander, Marju Orho-Melander, Jan Nilsson, Hans-Ulrich Häring, Erik Renström, Claes B. Wollheim, Gunnar Engström, Jianping Weng, Ewan R. Pearson, Paul W. Franks, Morris F. White, Kevin L. Duffin, Allan Arthur Vaag, Markku Laakso, Norbert Stefan, Leif Groop, Yang De Marinis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Follistatin promotes in type 2 diabetes (T2D) pathogenesis in model animals and is elevated in patients with T2D. Here the authors report that plasma follistatin associates with increased risk of incident T2D in two longitudinal cohorts, and show tha
Externí odkaz:
https://doaj.org/article/718976e80f5648f99659b5ea904f47e5
Autor:
Hiddo J.L. Heerspink, Naveed Sattar, Imre Pavo, Axel Haupt, Kevin L. Duffin, Zhengyu Yang, Russell John Wiese, Katherine R. Tuttle, David Z.I. Cherney, Jochen Seufert
Publikováno v:
Diabetologie und Stoffwechsel.
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Growth/differentiation factor-15 (GDF-15) is a distant member of the transforming growth factor β (TGF-β) superfamily and is widely expressed in multiple mammalian tissues. Its expression is highly regulated and is often induced in response to cond
Externí odkaz:
https://doaj.org/article/e62acf91ab594e15a9557fc257b53462
Autor:
Hertzel C. Gerstein, Shun-Fu Lee, Guillaume Paré, M. Angelyn Bethel, Helen M. Colhoun, Anastasia Hoover, Mark Lakshmanan, Yanzhu Lin, Valentino Pirro, Hui-Rong Qian, Giacomo Ruotolo, Lars Ryden, Jonathan M. Wilson, Kevin L. Duffin
OBJECTIVE The glucagon-like peptide-1 receptor agonist dulaglutide reduced MACE in the Researching Cardiovascular Events with a Weekly Incretin in Diabetes (REWIND) trial. This article expores the relationship of selected biomarkers to both dulagluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2640ca757c8cf50993017da4bd7b9737
https://doi.org/10.2337/figshare.22120097
https://doi.org/10.2337/figshare.22120097
Autor:
Hiroki Kobayashi, Helen C. Looker, Eiichiro Satake, Francesca D’Addio, Jonathan M. Wilson, Pierre Jean Saulnier, Zaipul I. Md Dom, Kristina O’Neil, Katsuhito Ihara, Bozena Krolewski, Hannah S. Badger, Adriana Petrazzuolo, Domenico Corradi, Andrzej Galecki, Parker C. Wilson, Behzad Najafian, Michael Mauer, Monika A. Niewczas, Alessandro Doria, Benjamin D. Humphreys, Kevin L. Duffin, Paolo Fiorina, Robert G. Nelson, Andrzej S. Krolewski
Publikováno v:
Sci Transl Med
Circulating proteins associated with transforming growth factor-β (TGF-β) signaling are implicated in the development of diabetic kidney disease (DKD). No study has comprehensively examined which of these proteins are involved in the pathogenesis o
Autor:
Katherine R. Tuttle, Jonathan Matthew Wilson, Yanzhu Lin, Hui-Rong Qian, Federica Genovese, Morten Asser Karsdal, Kevin L. Duffin, Fady T Botros
Publikováno v:
American Journal of Nephrology.
Introduction: In the AWARD-7 study in patients with type 2 diabetes and moderate-to-severe chronic kidney disease, once-weekly dulaglutide slowed the decline in estimated glomerular filtration rate (eGFR) and decreased the urine albumin/creatinine ra
Autor:
Kenneth D. Roth, Valentina Pirro, Kevin L. Duffin, Jonathan M. Wilson, Yanzhu Lin, Jill A. Willency, Axel Haupt, Paul L. Milligan, Christopher B. Newgard, Giacomo Ruotolo
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 107:363-378
Context Tirzepatide substantially reduced hemoglobin A1c (HbA1c) and body weight in subjects with type 2 diabetes (T2D) compared with the glucagon-like peptide 1 receptor agonist dulaglutide. Improved glycemic control was associated with lower circul
Autor:
Hiddo J L, Heerspink, Naveed, Sattar, Imre, Pavo, Axel, Haupt, Kevin L, Duffin, Zhengyu, Yang, Russell J, Wiese, Katherine R, Tuttle, David Z I, Cherney
Publikováno v:
The Lancet Diabetes and Endocrinology, 10(11), 774-785. ELSEVIER SCIENCE INC
Background: In the SURPASS-4 trial, the dual GIP and GLP-1 receptor agonist tirzepatide reduced HbA1c concentrations, bodyweight, and blood pressure more than titrated daily insulin glargine in people with type 2 diabetes inadequately controlled on o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e32ba5e7ec793343b56a3763241de9
https://research.rug.nl/en/publications/9fd182d5-8590-4916-a1a3-8301509299bf
https://research.rug.nl/en/publications/9fd182d5-8590-4916-a1a3-8301509299bf
Autor:
Guanlin Li, Grace Lai-Hung Wong, Terry Cheuk-Fung Yip, Qingxiong Tan, Huapeng Lin, Jonathan Matthew Wilson, Lenden M Bowsman, Joseph V Haas, Anthony Wing-Hung Chan, Howard Ho-Wai Leung, Xinrong Zhang, Yee-Kit Tse, Sally She-Ting Shu, Angel Mei-Ling Chim, Henry Lik-Yuen Chan, Pong Chi Yuen, Vincent Wai-Sun Wong, Kevin L. Duffin, Yu Chen
Background: A number of protein biomarkers have been proposed for the assessment of non-alcoholic fatty liver disease (NAFLD), but few have been externally validated and directly compared. The aim of this study was to compare the diagnostic accuracie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd9b3fef1e7201d42071066eede5d386
https://doi.org/10.21203/rs.3.rs-2118271/v1
https://doi.org/10.21203/rs.3.rs-2118271/v1