Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kevin L, Allen"'
Autor:
Kevin L Allen, Jennifer Cann, Weiguang Zhao, Norman Peterson, Michelle Lazzaro, Haihong Zhong, Herren Wu, William F Dall'Acqua, M Jack Borrok, Melissa M Damschroder, Ping Tsui, Qing Li
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0252060 (2021)
[This corrects the article DOI: 10.1371/journal.pone.0234268.].
Externí odkaz:
https://doaj.org/article/51640645047d4adba46ece38f8fabcce
Autor:
Kevin L Allen, Jennifer Cann, Weiguang Zhao, Norman Peterson, Michelle Lazzaro, Haihong Zhong, Herren Wu, William F Dall'Acqua, M Jack Borrok, Melissa M Damschroder, Ping Tsui, Qing Li
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234268 (2020)
Annexin A1 (anxA1) is an immunomodulatory protein that has been proposed as a tumor vascular target for antitumor biologic agents, yet to date the vascular expression of anxA1 in specific tumor indications has not been systematically assessed. Attemp
Externí odkaz:
https://doaj.org/article/0083d0c4b3bf4781a3221ea58fe585e7
Autor:
Qing Li, William Dall'acqua, Chingshen Chan, Richard N. Hanna, Norman C. Peterson, Alex Alfaro, José Luís Guedes dos Santos, Kevin L Allen, M. Jack Borrok, Herren Wu
Publikováno v:
ACS chemical biology. 15(4)
Efficacious use of therapeutic gene delivery via nanoparticles is hampered by the challenges associated with targeted delivery to tissues of interest. Systemic administration of lipid nanoparticle (LNP)-encapsulated mRNA leads to a protein expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518ad2e466339bcf890a8a4e07d5931c
https://pubmed.ncbi.nlm.nih.gov/32155049
https://pubmed.ncbi.nlm.nih.gov/32155049
Autor:
Norman C. Peterson, Jason White, Keith W Rickert, M. Jack Borrok, Kevin L Allen, William Dall'acqua, Lu Shan, Ping Tsui, Kyle Kuszpit, Richard N. Hanna, Qing Li, Arnita Barnes, Herren Wu
Publikováno v:
Molecular Pharmaceutics.
Targeted strategies to deliver and retain drugs to kidneys are needed to improve drug accumulation and efficacy in a myriad of kidney diseases. These drug delivery systems show potential for improving the therapeutic windows of drugs acting in the ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b40c2786c81a544dd2d2842429b7bf7
https://doi.org/10.1021/acs.molpharmaceut.9b00939
https://doi.org/10.1021/acs.molpharmaceut.9b00939
Autor:
Qing, Li, Norman, Peterson, Richard N, Hanna, Kyle, Kuszpit, Jason, White, Kevin L, Allen, Arnita, Barnes, Keith W, Rickert, Lu, Shan, Herren, Wu, William F, Dall'Acqua, Ping, Tsui, M Jack, Borrok
Publikováno v:
Molecular pharmaceutics. 17(2)
Targeted strategies to deliver and retain drugs to kidneys are needed to improve drug accumulation and efficacy in a myriad of kidney diseases. These drug delivery systems show potential for improving the therapeutic windows of drugs acting in the ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75db3937acf4248ee8829b3cfa9c3bf5
https://pubmed.ncbi.nlm.nih.gov/31841002
https://pubmed.ncbi.nlm.nih.gov/31841002
Autor:
William Dall'acqua, Kevin L Allen, Keith W Rickert, Jason White, Kim Rosenthal, Ping Tsui, Norman C. Peterson, Qing Li, Chris Lloyd, Xizhe Gao, M. Jack Borrok, Herren Wu
Publikováno v:
Journal of Controlled Release. 279:126-135
The accumulation, dissemination and clearance of monoclonal antibody-based therapeutics or imaging reagents targeting tumor associated antigens is governed by several factors including affinity, size, charge, and valency. Tumor targeting antibody fra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eeb1e87904ba1ce567ceb02a6d38b11
https://doi.org/10.1016/j.jconrel.2018.04.013
https://doi.org/10.1016/j.jconrel.2018.04.013
Autor:
Balakumar Vijayakrishnan, Qing Li, Philip Howard, M. Jack Borrok, Arnaud C. Tiberghien, Keith W Rickert, Allison M. Barrett, Kevin L Allen, Changshou Gao, Ping Tsui, William Dall'acqua, R Jim Christie, Jay Harper, Marcello Marelli, Rhiannon Beard, Herren Wu
Publikováno v:
Bioconjugate chemistry. 30(4)
Despite some clinical success with antibody-drug conjugates (ADCs) in patients with solid tumors and hematological malignancies, improvements in ADC design are still desirable due to the narrow therapeutic window of these compounds. Tumor-targeting a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1daefaf386f5538098578d7d47f70b56
https://pubmed.ncbi.nlm.nih.gov/30912649
https://pubmed.ncbi.nlm.nih.gov/30912649
Autor:
Norman C. Peterson, Michelle Lazzaro, Jennifer Cann, Kevin L. Allen, Weiguang Zhao, Haihong Zhong, Qing Li, Ping Tsui, William F Dall'Acqua, Herren Wu, Melissa Damschroder, M. Jack Borrok
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0252060 (2021)
Annexin A1 (anxA1) is an immunomodulatory protein that has been proposed as a tumor vascular target for antitumor biologic agents, yet to date the vascular expression of anxA1 in specific tumor indications has not been systematically assessed. Attemp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422b2c510cf4d52b47dae81db2add409
https://doi.org/10.1371/journal.pone.0252060
https://doi.org/10.1371/journal.pone.0252060
Autor:
Supriyo De, Tennison L. Malcolm, Pradeep K. Chatterjee, Ken R. Harewood, Kevin L. Allen, Leighcraft A. Shakes
Publikováno v:
Nucleic Acids Research
An enhancer within intron 1 of the amyloid precursor protein gene (APPb) of zebrafish is identified functionally using a novel approach. Bacterial artificial chromosomes (BACs) were retrofitted with enhancer traps, and expressed as transgenes in zebr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd738e5a30dc5a7bbd1e2241ffe5100
http://europepmc.org/articles/PMC2577333
http://europepmc.org/articles/PMC2577333
Autor:
Saïd Kourrich, Mark J. Thomas, José O. Colón-Sáez, Kevin Wickman, Kirill A. Martemyanov, Keqiang Xie, Kevin L. Allen
Publikováno v:
Nature neuroscience
The type 5 G protein beta subunit (Gbeta5) can form complexes with members of the regulator of G protein signaling 7 (RGS7) family, but its relevance to neuronal G protein signaling is unclear. We found that mouse RGS7-Gbeta5 complexes bound to G pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe1ca8d2c1c2312f7c4090090873f14
http://europepmc.org/articles/PMC2876203
http://europepmc.org/articles/PMC2876203