Zobrazeno 1 - 10 of 90 pro vyhledávání: '"Kevin K.-C. Liu"'
1
Akademický článek
Racemic N-methyl-4-[2-(methylsulfanyl)pyrimidin-4-yl]-1-(tetrahydrofuran-3-yl)-1H-pyrazol-5-amine
Autor: Alex Yanovsky, Antonio DiPasquale, Arnold L. Rheingold, Kevin K.-C. Liu, Zhengyu Liu
Publikováno v: Acta Crystallographica Section E, Vol 65, Iss 5, Pp o1089-o1089 (2009)
The title compound, C13H17N5OS, was obtained by cycloaddition of 2-[2-(methylsulfanyl)pyrimidin-4-yl]-3-oxopropanenitrile with (tetrahydrofuran-3-yl)hydrazine dihydrochloride and subsequent N-methylation of 4-[2-(methylsulfanyl)pyrimidin-4-yl]-1-(tet
Externí odkaz: https://doaj.org/article/e1bc7a5eab4e47998b656704ffc7df93
Zobrazit plný text záznamu
2
Akademický článek
(R)-4-[2-(Methylsulfanyl)pyrimidin-4-yl]-1-(tetrahydrofuran-3-yl)-1H-pyrazol-5-amine
Autor: Zhengyu Liu, Kevin K.-C. Liu, Jeff Elleraas, Arnold L. Rheingold, Antonio DiPasquale, Alex Yanovsky
Publikováno v: Acta Crystallographica Section E, Vol 65, Iss 4, Pp o697-o697 (2009)
The title compound, C12H15N5OS, was obtained by reaction of 2-(2-(methylthio)pyrimidin-4-yl)-3-oxopropanenitrile with (tetrahydrofuran-3-yl)hydrazine dihydrochloride, and the racemic product was subsequently separated by chiral chromatography (first
Externí odkaz: https://doaj.org/article/107453a2bc404692bb6d04bc2ac2e6f1
Zobrazit plný text záznamu
6
Data from Targeting Small Cell Lung Cancer Harboring PIK3CA Mutation with a Selective Oral PI3K Inhibitor PF-4989216
Autor: Min-Jean Yin, Tod Smeal, Qing Zong, Michael Zientek, Chunze Li, Heather Estrella, JinJiang Zhu, Kevin K.-C. Liu, Pramod P. Mehta, Sangita M. Baxi, Marlena Walls
Purpose: Constitutive activation of phosphoinositide 3-kinase (PI3K) occurs frequently in many human tumors via either gene mutation in the p110α catalytic subunit of PI3K or functional loss of tumor suppressor PTEN. Patients with small-cell lung ca
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7977a47dd31fb4a5283b4eafce56aa2a
https://doi.org/10.1158/1078-0432.c.6521870.v1
Zobrazit plný text záznamu
8
Direct photochemical cross-coupling between aliphatic acids and BF3K salts
Autor: Bingqing Tang, Hugh Y. Zhu, Zhuming Sun, Kevin K.-C. Liu
Publikováno v: Chemical Communications. 56:1294-1297
We describe a novel photoredox hetero-coupling reaction of two C (sp3) radicals from aliphatic acids or BF3K salts. The kinetic differences in radical persistence provide cross-selectivity, using an organic photoredox catalyst and an oxidant with vis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1bf9391ac9dbdb8c2df5e1c109d5b364
https://doi.org/10.1039/c9cc09164e
Zobrazit plný text záznamu
9
Direct photochemical cross-coupling between aliphatic acids and BF
Autor: Zhuming, Sun, Bingqing, Tang, Kevin K-C, Liu, Hugh Y, Zhu
Publikováno v: Chemical communications (Cambridge, England). 56(8)
We describe a novel photoredox hetero-coupling reaction of two C (sp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c538aa3943b8bd785a56d7c7c95d50d0
https://pubmed.ncbi.nlm.nih.gov/31904043
Zobrazit plný text záznamu
10
Synthetic Approaches to the New Drugs Approved During 2015
Autor: Christopher J. O’Donnell, Carolyn A. Leverett, Sarah J. Fink, Kevin K.-C. Liu, Hong X. Ding, Andrew C. Flick, Robert E. Kyne
Publikováno v: Journal of Medicinal Chemistry. 60:6480-6515
New drugs introduced to the market every year represent privileged structures for particular biological targets. These new chemical entities (NCEs) provide insight into molecular recognition while serving as leads for designing future new drugs. This
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1c3321b98f3a63a027a7f2359e2458
https://doi.org/10.1021/acs.jmedchem.7b00010
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje