Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kevin K. Desai"'
Publikováno v:
Nucleic Acids Research
Archease is a 16-kDa protein that is conserved in all three domains of life. In diverse bacteria and archaea, the genes encoding Archease and the tRNA ligase RtcB are localized into an operon. Here we provide a rationale for this operon organization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd9d8999e7b662ee91bdfb570ee0c182
http://europepmc.org/articles/PMC3973293
http://europepmc.org/articles/PMC3973293
Publikováno v:
Biochemistry. 52:2518-2525
RtcB is an atypical RNA ligase that joins either 2',3'-cyclic phosphate or 3'-phosphate termini to 5'-hydroxyl termini. In contrast to typical RNA ligases, which rely on ATP and Mg(II), catalysis by RtcB is dependent on GTP and Mn(II) with ligation p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8bc3dd27f5b02dc43e7277a5991a2bc
https://doi.org/10.1021/bi4002375
https://doi.org/10.1021/bi4002375
Autor:
Kevin K. Desai, Brian G. Miller
Publikováno v:
Proceedings of the National Academy of Sciences. 107:17968-17973
Microbial niches contain toxic chemicals capable of forcing organisms into periods of intense natural selection to afford survival. Elucidating the mechanisms by which microbes evade environmental threats has direct relevance for understanding and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fac51ca42818292df35f06ac4df211d
https://doi.org/10.1073/pnas.1007559107
https://doi.org/10.1073/pnas.1007559107
Autor:
Kevin K. Desai, Brian G. Miller
Publikováno v:
Protein Engineering Handbook, Volume 1 & Volume 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::495876cf53c8757648f2c7a8fbb9edfe
https://doi.org/10.1002/9783527634026.ch13
https://doi.org/10.1002/9783527634026.ch13
Publikováno v:
RNA (New York, N.Y.). 21(11)
RtcB is a noncanonical RNA ligase that joins either 2′,3′-cyclic phosphate or 3′-phosphate termini to 5′-hydroxyl termini. The genes encoding RtcB and Archease constitute a tRNA splicing operon in many organisms. Archease is a cofactor of Rtc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d643d22b56e25d53f56dfce1436fb5f3
https://pubmed.ncbi.nlm.nih.gov/26385509
https://pubmed.ncbi.nlm.nih.gov/26385509
Autor:
Kevin K. Desai, Ronald T. Raines
Publikováno v:
Biochemistry. 51:1333-1335
The RNA ligase RtcB is conserved in all domains of life, and is essential for tRNA maturation in archaea and metazoa. Here we show that bacterial and archaeal RtcB catalyze the GTP-dependent ligation of RNA with 3′-phosphate and 5′-hydroxyl termi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3888c7605569e9dbcb26bc5fa3f7ddb
https://doi.org/10.1021/bi201921a
https://doi.org/10.1021/bi201921a
Publikováno v:
RNA (New York, N.Y.). 20(10)
RNA 3′-phosphate cyclase (RtcA) catalyzes the ATP-dependent cyclization of a 3′-phosphate to form a 2′,3′-cyclic phosphate at RNA termini. Cyclization proceeds through RtcA–AMP and RNA(3′)pp(5′)A covalent intermediates, which are analog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194942eab966d69bbf1d77df410dcf5c
https://pubmed.ncbi.nlm.nih.gov/25161314
https://pubmed.ncbi.nlm.nih.gov/25161314
Autor:
Kenneth A. Iczkowski, Seakwoo Lee, Kevin J. Wu, Mark D. Roycik, Winston Tan, Qing-Xiang Amy Sang, Robert G. Newcomer, Kevin K. Desai, Yun Ge Zhao
Publikováno v:
Cell research. 16(9)
The identification of novel biomarkers for early prostate cancer diagnosis is highly important because early detection and treatment are critical for the medical management of patients. Disruption in the continuity of both the basal cell layer and ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dace9fe1dfb16e165e8508d764fc204a
https://pubmed.ncbi.nlm.nih.gov/16971961
https://pubmed.ncbi.nlm.nih.gov/16971961
Publikováno v:
IEEE transactions on visualization and computer graphics [IEEE Trans Vis Comput Graph] 2024 May; Vol. 30 (5), pp. 2368-2378. Date of Electronic Publication: 2024 Apr 23.
Autor:
Krishna H; Division of Cardiology, University of Illinois at Chicago, Chicago, Illinois; Jesse Brown VA Medical Center, Chicago, Illinois., Desai K; Department of Medicine, University of Illinois at Chicago, Chicago, Illinois., Slostad B; Bluhm Cardiovascular Institute, Northwestern University, Chicago, Illinois., Bhayani S; Department of Medicine, University of Illinois at Chicago, Chicago, Illinois., Arnold JH; Department of Medicine, University of Illinois at Chicago, Chicago, Illinois., Ouwerkerk W; National Heart Centre Singapore, Singapore; Department of Dermatology, Amsterdam UMC, Amsterdam, Netherlands., Hummel Y; Us2.ai, Singapore., Lam CSP; National Heart Centre Singapore, Singapore; Duke-NUS Medical School, Singapore., Ezekowitz J; Canadian VIGOUR Centre, University of Alberta, Edmonton, Alberta, Canada., Frost M; Us2.ai, Singapore., Jiang Z; Us2.ai, Singapore., Equilbec C; Us2.ai, Singapore., Twing A; Division of Cardiology, University of Illinois at Chicago, Chicago, Illinois., Pellikka PA; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota., Frazin L; Division of Cardiology, University of Illinois at Chicago, Chicago, Illinois; Jesse Brown VA Medical Center, Chicago, Illinois., Kansal M; Division of Cardiology, University of Illinois at Chicago, Chicago, Illinois; Jesse Brown VA Medical Center, Chicago, Illinois. Electronic address: mmkansal@uic.edu.
Publikováno v:
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography [J Am Soc Echocardiogr] 2023 Jul; Vol. 36 (7), pp. 769-777. Date of Electronic Publication: 2023 Mar 22.