Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kevin K H Chow"'
Autor:
Vita S Salsman, Kevin K H Chow, Donald R Shaffer, Huseyin Kadikoy, Xiao-Nan Li, Claudia Gerken, Laszlo Perlaky, Leonid S Metelitsa, Xiuhua Gao, Meena Bhattacharjee, Karen Hirschi, Helen E Heslop, Stephen Gottschalk, Nabil Ahmed
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20267 (2011)
Cancer cells can live and grow if they succeed in creating a favorable niche that often includes elements from the immune system. While T lymphocytes play an important role in the host response to tumor growth, the mechanism of their trafficking to t
Externí odkaz:
https://doaj.org/article/8934db56267140b5836fc475bb10fb93
Publikováno v:
Journal of Immunology Research, Vol 2014 (2014)
Glioblastoma (GBM) is the most common primary brain tumor, and despite aggressive therapy with surgery, radiation, and chemotherapy, average survival remains at about 1.5 years. The highly infiltrative and invasive nature of GBM requires that alterna
Externí odkaz:
https://doaj.org/article/78a4a307c91b40828863d69924623594
Autor:
Meenakshi, Hegde, Amanda, Corder, Kevin K H, Chow, Malini, Mukherjee, Aidin, Ashoori, Yvonne, Kew, Yi Jonathan, Zhang, David S, Baskin, Fatima A, Merchant, Vita S, Brawley, Tiara T, Byrd, Simone, Krebs, Meng Fen, Wu, Hao, Liu, Helen E, Heslop, Stephen, Gottschalk, Stephen, Gottachalk, Eric, Yvon, Nabil, Ahmed
Publikováno v:
Molecular Therapy
Preclinical and early clinical studies have demonstrated that chimeric antigen receptor (CAR)-redirected T cells are highly promising in cancer therapy. We observed that targeting HER2 in a glioblastoma (GBM) cell line results in the emergence of HER