Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Kevin K, Lee"'
Autor:
Jaya Manjunath, BS, Viviane Liao, BS, Anusha Kambala, BS, Aaron Bao, BA, Alexander L. Kollhoff, MD, Emily Z. Ma, BS, Brenda Umenita Imo, MS, Hannah Cornman, BS, Sriya V. Reddy, BS, Kevin K. Lee, BS, Weiying Lu, BS, Selina M. Yossef, BA, Madan M. Kwatra, PhD, Shawn G. Kwatra, MD
Publikováno v:
JAAD International, Vol 16, Iss , Pp 97-102 (2024)
Background: Chronic pruritus (CP) is a poorly characterized condition associated with intense pruritus without a primary skin eruption. This condition tends to emerge more commonly in older adults, and there is limited research on triggering factors.
Externí odkaz:
https://doaj.org/article/4057541bba474abb8f97bd8604389b6b
Autor:
Jaya Manjunath, Varsha Parthasarathy, Marina Z. Joel, Junwen Deng, Emily Z. Ma, Kevin K. Lee, Thomas Pritchard, Shenghao Guo, Cissy Zhang, Madan M. Kwatra, Anne Le, Shawn G. Kwatra
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Chronic pruritus of unknown origin (CPUO) is characterized by chronic itch for 6 weeks or greater without an identifiable primary cause. Studies are needed to investigate circulating blood biomarkers to elucidate disease pathogenesis. The ob
Externí odkaz:
https://doaj.org/article/1acfa06fe5514aafb864c485e9168250
Autor:
Hannah L. Cornman, Jaya Manjunath, Sriya V. Reddy, Jackson Adams, Ahmad Rajeh, Christeen Samuel, Aaron Bao, Ryan Zhao, Emily Z. Ma, Jason Shumsky, Thomas W. Pritchard, Brenda Umenita Imo, Alexander L. Kollhoff, Kevin K. Lee, Weiying Lu, Selina Yossef, Madan M. Kwatra, Shawn G. Kwatra
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Prurigo nodularis (PN) is a chronic inflammatory skin disease that is associated with variability in peripheral blood eosinophil levels and response to T-helper 2 targeted therapies (Th2). Our objective was to determine whether circulating i
Externí odkaz:
https://doaj.org/article/ca930731bc40459eb67e7977f3cba22a
Autor:
Anusha Kambala, BS, Alexander L. Kollhoff, MD, Elena Wei, BS, Kevin K. Lee, BA, Hannah Cornman, BS, Emily Z. Ma, BA, Jaya Manjunath, BS, Brenda Umenita Imo, MS, Sriya V. Reddy, BS, Shawn G. Kwatra, MD
Publikováno v:
JAAD Case Reports, Vol 44, Iss , Pp 77-81 (2024)
Externí odkaz:
https://doaj.org/article/2faa9e70b3b145f29db86d8df4afd22c
Autor:
Emily Z. Ma, Junwen Deng, Varsha Parthasarathy, Kevin K. Lee, Thomas Pritchard, Shenghao Guo, Cissy Zhang, Madan M. Kwatra, Anne Le, Shawn G. Kwatra
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ImportanceDisease models for atopic dermatitis (AD) have primarily focused on understanding underlying environmental, immunologic, and genetic etiologies. However, the role of metabolic mechanisms in AD remains understudied.ObjectiveTo investigate th
Externí odkaz:
https://doaj.org/article/57002ae2747249f9a2e5a2266c68fcea
Autor:
Eunjeong Kwon, Kristina Todorova, Jun Wang, Rastislav Horos, Kevin K. Lee, Victor A. Neel, Gian Luca Negri, Poul H. Sorensen, Sam W. Lee, Matthias W. Hentze, Anna Mandinova
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
The integrity of the stratified epithelia relies on controlled cell turnover but it is unclear how mRNA binding proteins regulates this. Here, the authors show that the RNA binding protein Y-box binding protein-1 translationally represses cytokines,
Externí odkaz:
https://doaj.org/article/ae77c37590464e83bc58037121dc3a32
Autor:
Chirag Vasavda, Guihong Wan, Mindy D. Szeto, Melika Marani, Nishadh Sutaria, Ahmad Rajeh, Chenyue Lu, Kevin K. Lee, Nga T.T. Nguyen, Waleed Adawi, Junwen Deng, Varsha Parthasarathy, Zachary A. Bordeaux, Matthew T. Taylor, Martin P. Alphonse, Madan M. Kwatra, Sewon Kang, Yevgeniy R. Semenov, Alexander Gusev, Shawn G. Kwatra
Publikováno v:
Journal of Investigative Dermatology.
Autor:
Anna Mandinova, Sam W. Lee, G. Paolo Dotto, Vihren Kolev, Hyung-Gu Kim, Ivan Kehayov, Eunjeong Kwon, Jun Wang, Kevin K. Lee, Kristina Todorova, Zehua Zhu
PDF file - 557KB, Supplementary Methods Suppl. Table 1. Primers used for real time and conventional RT-PCR . Suppl. Figure S1. RhoE expression is down-regulated in skin SCC tumors. Suppl. Figure S2. Notch activation does not induce expression of memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257b68ebaf4bd564cdba8ca336054e53
https://doi.org/10.1158/0008-5472.22393817.v1
https://doi.org/10.1158/0008-5472.22393817.v1
Autor:
Nishadh Sutaria, Melika Marani, Justin Choi, Youkyung Sophie Roh, Varsha Parthasarathy, Junwen Deng, Zachary A. Bordeaux, Matthew T. Taylor, Kevin K. Lee, Thomas Pritchard, Ali Alajmi, Waleed Adawi, Yevgeniy R. Semenov, Martin P. Alphonse, Shawn G. Kwatra
Publikováno v:
Journal of Dermatological Science. 105:130-136
There are limited data characterizing the association between renal disease and prurigo nodularis (PN).To characterize the association and describe mechanistic disease linkages between PN and renal comorbidities.We conducted a cross-sectional analysi
Autor:
Jay R. Patel, Marina Z. Joel, Kevin K. Lee, Anusha Kambala, Hannah Cornman, Olusola Oladipo, Matthew Taylor, June Deng, Varsha Parthasarathy, Karen Cravero, Melika Marani, Ryan Zhao, Sreenidhi Sankararam, Ruixiang Li, Thomas Pritchard, Vito Rebecca, Madan M. Kwatra, Won Jin Ho, Xinzhong Dong, Sewon Kang, Shawn G. Kwatra
Prurigo nodularis (PN) is an intensely pruritic, chronic inflammatory skin disease that disproportionately affects black patients. However, the pathogenesis of PN is poorly understood. We performed single-cell transcriptomic profiling, ligand recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b782d827eb61910bc76b863e06b77ac9
https://doi.org/10.1101/2023.01.29.526050
https://doi.org/10.1101/2023.01.29.526050