Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Kevin J. Stephanski"'
Autor:
Janet L. Wieber, James A. Nieman, Herbert M. Zerth, Brenda L. Schultz, Steven E. Heasley, Nancee L. Oien, Mary L. Knechtel, Ke Chen, Todd A. Hopkins, Michael W. Wathen, Kevin J. Stephanski, Richard A. Nugent, Sajiv Krishnan Nair
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:3039-3042
A series of C-2 pyrroloquinoline analogs designed to improve aqueous solubility were examined for herpesvirus polymerase and antiviral activity. Several analogs were identified that maintained the antiviral activity of the previous development candid
Autor:
Steven P. Tanis, Nancee L. Oien, Kevin J. Stephanski, Mary L. Knechtel, Janet L. Wieber, Timothy Parker, Perrault William R, Strohbach Joseph Walter, Malcom W. Moon, Todd A. Hopkins, Michael W. Wathen, Suvit Thaisrivongs
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(6)
Discovery efforts were focused on identifying a non-nucleoside antiviral for treating infections caused by human cytomegalovirus (HCMV) with equal or better potency and diminished toxicity compared to current therapeutics. This Letter describes the H