Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Kevin J. Schwartz"'
Autor:
Rajdeep Banerjee, Erin Weisenhorn, Kevin J. Schwartz, Kevin S. Myers, Jeremy D. Glasner, Nicole T. Perna, Joshua J. Coon, Rodney A. Welch, Patricia J. Kiley
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Pathogenicity islands and plasmids bear genes for pathogenesis of various Escherichia coli pathotypes. Although there is a basic understanding of the contribution of these virulence factors to disease, less is known about variation in regula
Externí odkaz:
https://doaj.org/article/46c78f9e257041319a1a801093a3653b
Autor:
Laura C. Ristow, Vy Tran, Kevin J. Schwartz, Lillie Pankratz, Andrew Mehle, John-Demian Sauer, Rodney A. Welch
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT The Escherichia coli hemolysin (HlyA) is a pore-forming exotoxin associated with severe complications of human urinary tract infections. HlyA is the prototype of the repeats-in-toxin (RTX) family, which includes LtxA from Aggregatibacter act
Externí odkaz:
https://doaj.org/article/07258d37f51446f99ca294545c1ad19d
Publikováno v:
Journal of Biological Chemistry. 295:2227-2238
The transferrin receptor (TfR) of the bloodstream form (BSF) of Trypanosoma brucei is a heterodimer comprising glycosylphosphatidylinositol (GPI)-anchored expression site–associated gene 6 (ESAG6 or E6) and soluble ESAG7. Mature E6 has five N-glyca
Autor:
Kevin J. Schwartz, Patricia J. Kiley, Rodney A. Welch, Jeremy D. Glasner, Nicole T. Perna, Erin Weisenhorn, Kevin S. Myers, Rajdeep Banerjee, Joshua J. Coon
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
mBio
mBio, Vol 11, Iss 2, p e00351-20 (2020)
mBio
mBio, Vol 11, Iss 2, p e00351-20 (2020)
Host iron restriction is a common mechanism for limiting the growth of pathogens. We compared the regulatory network controlled by Fur in uropathogenic E. coli (UPEC) to that of nonpathogenic E. coli K-12 to uncover strategies that pathogenic bacteri
Publikováno v:
J Biol Chem
The transferrin receptor (TfR) of the bloodstream form (BSF) of Trypanosoma brucei is a heterodimer comprising glycosylphosphatidylinositol (GPI)-anchored expression site–associated gene 6 (ESAG6 or E6) and soluble ESAG7. Mature E6 has five N-glyca
Autor:
Laura C. Ristow, Vy Tran, Kevin J. Schwartz, Lillie Pankratz, Andrew Mehle, John-Demian Sauer, Rodney A. Welch
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
The Escherichia coli hemolysin (HlyA) is a pore-forming exotoxin associated with severe complications of human urinary tract infections. HlyA is the prototype of the repeats-in-toxin (RTX) family, which includes LtxA from Aggregatibacter actinomycete
Autor:
Kevin J. Schwartz, Laura C. Ristow, Rodney A. Welch, Lillie Pankratz, John-Demian Sauer, Andrew Mehle, Vy Tran
Publikováno v:
mBio, Vol 10, Iss 4, p e01459-19 (2019)
mBio
mBio
Urinary tract infections are one of the most common bacterial infections worldwide. Uropathogenic Escherichia coli strains are responsible for more than 80% of community-acquired urinary tract infections. Although we have known for nearly a century t
Autor:
Tensin S Atruksang, Eric J. Battaglioli, Kevin J. Schwartz, Rene Welch, Mark A. Schembri, Kelvin G. K. Goh
Publikováno v:
mBio
mBio, Vol 9, Iss 4 (2018)
mBio, Vol 9, Iss 4, p e01360-18 (2018)
mBio, Vol 9, Iss 4 (2018)
mBio, Vol 9, Iss 4, p e01360-18 (2018)
Uropathogenic Escherichia coli (UPEC) is the most common etiologic agent of uncomplicated urinary tract infection (UTI). An important mechanism of gene regulation in UPEC is phase variation that involves inversion of a promoter-containing DNA element
Autor:
John Turk, Fong-Fu Hsu, James D. Bangs, Elitza S. Sevova, Kevin J. Schwartz, Michael A. Goren, Brian G. Fox
Publikováno v:
Journal of Biological Chemistry. 285:20580-20587
The Trypanosoma brucei genome has four highly similar genes encoding sphingolipid synthases (TbSLS1-4). TbSLSs are polytopic membrane proteins that are essential for viability of the pathogenic bloodstream stage of this human protozoan parasite and,
Autor:
Kevin J. Schwartz, Jason S. Silverman, Elitza S. Sevova, James D. Bangs, Shaheen S. Sutterwala, Ngii N. Tazeh
Publikováno v:
Eukaryotic Cell. 8:1352-1361
African trypanosomes are the causative agents of human trypanosomiasis (sleeping sickness). The pathogenic stage of the parasite has unique adaptations to life in the bloodstream of the mammalian host, including upregulation of endocytic and lysosoma