Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Kevin J. Ryan"'
Autor:
Kevin J. Ryan
Publikováno v:
Frontiers in Robotics and AI, Vol 10 (2023)
Understanding novelty and improvisation in music requires gathering insight from a variety of disciplines. One fruitful path for synthesizing these insights is via modeling. As such, my aim in this paper is to start building a bridge between traditio
Externí odkaz:
https://doaj.org/article/ef5d1bb76e824bacb5654198bf823413
Autor:
Lauren R. Schaff, Mina Lobbous, Dean Carlow, Ryan Schofield, Igor T. Gavrilovic, Alexandra M. Miller, Jacqueline B. Stone, Anna F. Piotrowski, Ugur Sener, Anna Skakodub, Edward P. Acosta, Kevin J. Ryan, Ingo K. Mellinghoff, Lisa M. DeAngelis, Louis B. Nabors, Christian Grommes
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background High-dose methotrexate (HD-MTX) has broad use in the treatment of central nervous system (CNS) malignancies but confers significant toxicity without inpatient hydration and monitoring. Glucarpidase is a bacterial recombinant enzym
Externí odkaz:
https://doaj.org/article/3e9f2e48ef674472afa6c947189513cd
Autor:
Alan Umfress, Sarbjit Singh, Kevin J. Ryan, Ayanabha Chakraborti, Florian Plattner, Yogesh Sonawane, Jayapal Reddy Mallareddy, Edward P. Acosta, Amarnath Natarajan, James A. Bibb
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cyclin-dependent kinase 5 (Cdk5) is a crucial regulator of neuronal signal transduction. Cdk5 activity is implicated in various neuropsychiatric and neurodegenerative conditions such as stress, anxiety, depression, addiction, Alzheimer’s disease, a
Externí odkaz:
https://doaj.org/article/f4abb12095324eafaf3ed9bba08dbea1
Publikováno v:
Frontiers in Psychology, Vol 13 (2022)
Much of our everyday, embodied action comes in the form of smooth coping. Smooth coping is skillful action that has become habituated and ingrained, generally placing less stress on cognitive load than considered and deliberative thought and action.
Externí odkaz:
https://doaj.org/article/769de4a177384f31a38325892e53b5f4
Autor:
Kevin J. Ryan, Shaun Gallagher
Publikováno v:
Frontiers in Psychology, Vol 11 (2020)
Ecological psychologists and enactivists agree that the best explanation for a large share of cognition is non-representational in kind. In both ecological psychology and enactivist philosophy, then, the task is to offer an explanans that does not re
Externí odkaz:
https://doaj.org/article/f5cf14261041438ab94c05109c6c5434
Autor:
Kevin J. Ryan JR.
Publikováno v:
Empirical Musicology Review, Vol 9, Iss 3-4, Pp 159-160 (2015)
Externí odkaz:
https://doaj.org/article/d2f8f216924b44fda9a9fea0166ecf4e
Autor:
Jennifer S, Guimbellot, Kevin J, Ryan, Justin D, Anderson, Kennedy L, Parker, Lauren, Victoria Odom, Steven M, Rowe, Edward P, Acosta
Publikováno v:
Pediatric Pulmonology. 57:2745-2753
Access to cystic fibrosis transmembrane conductance regulator (CFTR) modulators has been gradually increasing for people with cystic fibrosis, the first of which was ivacaftor, a CFTR potentiator that is part of all clinically available modulator tre
Autor:
Christos Vaklavas, Erica M. Stringer-Reasor, Ahmed M. Elkhanany, Kevin J. Ryan, Yufeng Li, Charles P. Theuer, Edward P. Acosta, Shi Wei, Eddy S. Yang, William E. Grizzle, Andres Forero-Torres
Purpose In nonmetastatic hormone receptor-positive and Her2-negative breast cancer, preoperative endocrine therapies can yield outcomes similar with chemotherapy. We evaluated the tolerability and preliminary antitumor activity of preoperative letroz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9169376e4e948e0e516012c68720fa61
https://doi.org/10.21203/rs.3.rs-2173087/v1
https://doi.org/10.21203/rs.3.rs-2173087/v1
Autor:
Edward P. Acosta, Megan Smith, Hector H. Gutierrez, Luz Helena Gutierrez Sanchez, Kevin J. Ryan, Jennifer S. Guimbellot, Janaina Nogueira Anderson, Kim W. Benner
Publikováno v:
J Cyst Fibros
The CFTR modulator combination elexacaftor/tezacaftor/ivacaftor (ETI) is a genetic mutation-targeted treatment in cystic fibrosis that results in profound improvements in clinical outcomes. Each of the compounds are substrates of CYP3A4/5, the cytoch
Autor:
Kevin J. Ryan, Jennifer S. Guimbellot, Alexander E. Dowell, Kedria D. Reed-Walker, Corenna D. Kerstner-Wood, Justin D. Anderson, Zhongyu Liu, Edward P. Acosta
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1213
The triple combination modulator therapy (ETI, elexacaftor (ELX), tezacaftor (TEZ), and ivacaftor (IVA)) is a recent advancement for the care of patients with cystic fibrosis. To aid in the development of clinical pharmacokinetics studies of this tre