Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Kevin J. McCarthy"'
Publikováno v:
Bioengineering, Vol 11, Iss 4, p 393 (2024)
In current-generation designs of total primary hip joint replacement, the prostheses are fabricated from alloys. The modulus of elasticity of the alloy is substantially higher than that of the surrounding bone. This discrepancy plays a role in a phen
Externí odkaz:
https://doaj.org/article/0d153a0770bc4da380bf5a84295ee413
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The fractional clearance of proteins as measured in healthy human subjects increases 10,000–100,000- fold when studied in nephrotic patients. This remarkable increase cannot be accounted for by extracellular biophysical mechanisms centered at the g
Externí odkaz:
https://doaj.org/article/cba16c62a9e6405eaec6f713c466364f
Autor:
Ana C. Vaz, Mandy Karnauskas, Claire B. Paris, Jennifer C. Doerr, Ronald L. Hill, Calusa Horn, Margaret H. Miller, Melissa Neuman, Kevin J. McCarthy, Nicholas A. Farmer
Publikováno v:
Frontiers in Marine Science, Vol 9 (2022)
The queen conch, Aliger gigas, is an endemic and iconic marine gastropod of the Wider Caribbean region that has been harvested for thousands of years. Conch are slow-moving and require contact to mate; overfishing has reduced populations in many area
Externí odkaz:
https://doaj.org/article/9abe748e6b3842e18cf5284287058cbe
Autor:
Sudha Sharma, Susmita Bhattarai, Hosne Ara, Grace Sun, Daret K. St Clair, Md Shenuarin Bhuiyan, Christopher Kevil, Megan N. Watts, Paari Dominic, Takahiko Shimizu, Kevin J. McCarthy, Hong Sun, Manikandan Panchatcharam, Sumitra Miriyala
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101740- (2020)
Electrophilic aldehyde (4-hydroxynonenal; 4-HNE), formed after lipid peroxidation, is a mediator of mitochondrial dysfunction and implicated in both the pathogenesis and the progression of cardiovascular disease. Manganese superoxide dismutase (MnSOD
Externí odkaz:
https://doaj.org/article/2e80799244c74b9aa7443b34abaa0a5a
Autor:
Mini Chandra, Diana Escalante-Alcalde, Md. Shenuarin Bhuiyan, Anthony Wayne Orr, Christopher Kevil, Andrew J. Morris, Hyung Nam, Paari Dominic, Kevin J. McCarthy, Sumitra Miriyala, Manikandan Panchatcharam
Publikováno v:
Redox Biology, Vol 14, Iss , Pp 261-271 (2018)
Lipid Phosphate phosphatase 3 (LPP3), encoded by the Plpp3 gene, is an enzyme that dephosphorylates the bioactive lipid mediator lysophosphatidic acid (LPA). To study the role of LPP3 in the myocardium, we generated a cardiac specific Plpp3 deficient
Externí odkaz:
https://doaj.org/article/487d20f3df614f78b25bf66f5fd64fdc
Autor:
Kevin J. McCarthy
Publikováno v:
Kidney International
The endothelial glycocalyx is a key component of the glomerular filtration barrier. We have shown that matrix metalloproteinase (MMP)-mediated syndecan 4 shedding is a mechanism of glomerular endothelial glycocalyx damage in vitro, resulting in incre
Autor:
Molly H. Stevens, Adyan B. Rios, Vivian M. Matter, Kevin J. McCarthy, Shannon L. Cass-Calay, William J. Harford, Nancie J. Cummings, Skyler R. Sagarese, Meaghan Bryan
Publikováno v:
North American Journal of Fisheries Management. 38:507-537
Autor:
Hyung Wook Nam, Md. Shenuarin Bhuiyan, Kevin J. McCarthy, Sumitra Miriyala, Paari Dominic, Andrew J. Morris, Manikandan Panchatcharam, Anthony W Orr, Diana Escalante-Alcalde, Christopher G. Kevil, Mini Chandra
Publikováno v:
Redox Biology, Vol 14, Iss, Pp 261-271 (2018)
Redox Biology
Redox Biology
Lipid Phosphate phosphatase 3 (LPP3), encoded by the Plpp3 gene, is an enzyme that dephosphorylates the bioactive lipid mediator lysophosphatidic acid (LPA). To study the role of LPP3 in the myocardium, we generated a cardiac specific Plpp3 deficient
Autor:
Linda J. Walters, Havalend E. Steinmuller, Christian J. Pilato, Kevin J. McCarthy, Lisa G. Chambers, Stephanie A. Gaspar, Paul Sacks
Publikováno v:
Estuaries and Coasts. 41:784-799
The restoration of dead/degraded oyster reefs is increasingly pursued worldwide to reestablish harvestable populations or renew ecosystem services. Evidence suggests that oysters can improve water quality, but less is known about the role of associat
Autor:
Kevin J. McCarthy, Md. Shenuarin Bhuiyan, Sumitra Miriyala, Manikandan Panchatcharam, Diana Escalante Alcalde, Christopher G. Kevil
Publikováno v:
Circulation Research. 125
The bioactive lysophosphatidic acid (LPA) plays a well-known role in atherosclerotic disease, whereas, its role in myocardial function remains virtually unexplored. Following acute myocardial infarction, serum LPA concentration rises by six-fold over