Zobrazeno 1 - 10
of 411
pro vyhledávání: '"Kevin J. Catt"'
Autor:
G. Karina Parra-Mercado, Alma M. Fuentes-Gonzalez, Judith Hernandez-Aranda, Monica Diaz-Coranguez, Frank M. Dautzenberg, Kevin J. Catt, Richard L. Hauger, J. Alberto Olivares-Reyes
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
In the present study, we determined the cellular regulators of ERK1/2 and Akt signaling pathways in response to human CRF1 receptor (CRF1R) activation in transfected COS-7 cells. We found that Pertussis Toxin (PTX) treatment or sequestering Gβγ red
Externí odkaz:
https://doaj.org/article/0f469014d60e48bdb342ec1765ed2af7
Autor:
Patrick Vanderheyden, Thomas Unger, Hamiyet Unal, Kalyan Tirupula, Pieter B. M. W. M. Timmermans, Walter G. Thomas, Jacqueline Kemp, Sadashiva Karnik, Tadashi Inagami, Ahsan Husain, László Hunyady, Mastgugu Horiuchi, Theodore L. Goodfriend, Emanuel Escher, Satoru Eguchi, Khuraijam Dhanachandra Singh, Marc De Gasparo, Kevin J. Catt, Kenneth E. Bernstein, Wayne Alexander
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
The actions of angiotensin II (Ang II) are mediated by AT1 and AT2 receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Angiotensin receptors [63, 155]), which have around 30% sequence similarity. The decapeptide angiotensin I, the octa
Autor:
Citlaly Gutierrez-Rodelo, Araceli Arellano-Plancarte, Judith Hernandez-Aranda, Huguet V. Landa-Galvan, G. Karina Parra-Mercado, Nicole J. Moreno-Licona, Karla D. Hernandez-Gonzalez, Kevin J. Catt, Rafael Villalobos-Molina, J. Alberto Olivares-Reyes
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 11; Pages: 6048
Angiotensin II (Ang II) is a critical regulator of insulin signaling in the cardiovascular system and metabolic tissues. However, in adipose cells, the regulatory role of Ang II on insulin actions remains to be elucidated. The effect of Ang II on ins
Autor:
Nigel J. M. Birdsall, Stephen J Lolait, Hans-Jürgen Wester, Paul L. Chazot, Sadashiva S. Karnik, Simon D. Harding, Celine Valant, Stephen P.H. Alexander, Olivier Civelli, Zsolt Csaba, Mastgugu Horiuchi, Khuraijam Dhanachandra Singh, Theodore L. Goodfriend, Morley D. Hollenberg, Duuamene Nyimanu, Shlomo Melmed, G. Enrico Rovati, Xavier Norel, Leigh A. Stoddart, Klemens Kaupmann, Robyn Macrae, Nicholas D. Holliday, Deborah L. Segaloff, Justo P. Castaño, Tony Ngo, Gordon Dent, Jean-Martin Beaulieu, Thomas L Williams, Antonia Cianciulli, Paweł Kozielewicz, Xaria X. Li, Jyrki P. Kukkonen, Craig A. McArdle, John D. Lee, Philippe Rondard, Steven D. Douglas, Hubert Vaudry, Khaled A. Al-Hosaini, Nan Chiang, Bernhard Bettler, Giovanni Tulipano, Corinne Bousquet, Karen J. Gregory, Craig Gerard, Robert T. Jensen, Stefan Schulz, Rithwik Ramachandran, Ross A. D. Bathgate, Deepa Jonnalagadda, David M. Thal, Takio Kitazawa, Manisha Ray, Bice Chini, Thomas Unger, Marta Fumagalli, Jean-Pierre Vilardaga, Donald T. Ward, Roger G. Pertwee, Stefan Offermanns, Marvin C. Gershengorn, Marc Parmentier, Pieter Timmermans, Eamonn Kelly, Yukihiko Sugimoto, Hamiyet Unal, Vincenzo Mitolo, Alistair Mathie, Emma L. Veale, Andrew L. Gundlach, Anthony P. Davenport, Mark T. Quinn, Jérôme Leprince, Christa E. Müller, Geoffrey Burnstock, Akos Heinemann, Jacqueline R. Kemp, Richard D. Ye, Bernard Mouillac, Roger J. Summers, Raul R. Gainetdinov, Girolamo Calò, Philip N. Murphy, Amelie Lupp, Kalyan C. Tirupula, Walter G. Thomas, Julien Hanson, Ahsan Husain, Katie Leach, Lucie H. Clapp, Hans Bräuner-Osborne, Gunnar Schulte, Kenneth E. Bernstein, Jean Mazella, Torsten Schöneberg, Satoru Eguchi, Martin C. Michel, Maria Antonietta Panaro, Kevin J. Catt, Rainer K. Reinscheid, Hans-Jürgen Kreienkamp, Wayne R. Alexander, Emanuel Escher, Anne Marie O'Carroll, Magnus Bäck, Laurence J. Miller, Jane F. Armstrong, Chiara Ruzza, Trent M. Woodruff, Daniel Hoyer, Chengcan Yao, Maria P. Abbracchio, John A. Peters, Gary B. Willars, Jean-Philippe Pin, David Vaudry, Debbie L. Hay, François Boulay, Davide Lecca, Eric R. Prossnitz, Arthur Christopoulos, Victoria A. Blaho, Yasuyuki Kihara, Charles Kennedy, Christopher Southan, László Hunyady, Pascal Dournaud, Fernand Gobeil, Cyril Goudet, Charles N. Serhan, Claes Dahlgren, Jörg Hamann, Tobias Langenhan, Ralf Jockers, Nicholas M. Barnes, Jean-Louis Nahon, Richard L. Hauger, Adam J. Pawson, Gareth J. Sanger, Tung Fong, Susan E. Leeman, Elena Faccenda, Edward J. Filardo, Valerie P. Tan, Marc de Gasparo, Ji Ming Wang, Jamie A. Davies, Jerold Chun, Stefania Ceruti, Tadashi Inagami, Réjean Couture, Kenneth A. Jacobson, Patrick Vanderheyden, Adriaan P. IJzerman, Janet J. Maguire, Christopher S. Walker
Publikováno v:
British Journal of Pharmacology, 178, S27-S156. Wiley
Alexander, S P, Christopoulos, A, Davenport, A P, Kelly, E, Mathie, A, Peters, J A, Veale, E L, Armstrong, J F, Faccenda, E, Harding, S D, Pawson, A J, Southan, C, Davies, J A, Abbracchio, M P, Alexander, W, Al-Hosaini, K, Bäck, M, Barnes, N M, Bathgate, R, Beaulieu, J-M, Bernstein, K E, Bettler, B, Birdsall, N J M, Blaho, V, Boulay, F, Bousquet, C, Bräuner-Osborne, H, Burnstock, G, Caló, G, Castaño, J P, Catt, K J, Ceruti, S, Chazot, P, Chiang, N, Chini, B, Chun, J, Cianciulli, A, Civelli, O, Clapp, L H, Couture, R, Csaba, Z, Dahlgren, C, Dent, G, Singh, K D, Douglas, S D, Dournaud, P, Eguchi, S, Escher, E, Filardo, E J, Fong, T, Fumagalli, M, Gainetdinov, R R, Gasparo, M D, Gerard, C, Gershengorn, M, Gobeil, F, Goodfriend, T L, Goudet, C, Gregory, K J, Gundlach, A L, Hamann, J, Hanson, J, Hauger, R L, Hay, D L, Heinemann, A, Hollenberg, M D, Holliday, N D, Horiuchi, M, Hoyer, D, Hunyady, L, Husain, A, IJzerman, A P, Inagami, T, Jacobson, K A, Jensen, R T, Jockers, R, Jonnalagadda, D, Karnik, S, Kaupmann, K, Kemp, J, Kennedy, C, Kihara, Y, Kitazawa, T, Kozielewicz, P, Kreienkamp, H-J, Kukkonen, J P, Langenhan, T, Leach, K, Lecca, D, Lee, J D, Leeman, S E, Leprince, J, Li, X X, Williams, T L, Lolait, S J, Lupp, A, Macrae, R, Maguire, J, Mazella, J, McArdle, C A, Melmed, S, Michel, M C, Miller, L J, Mitolo, V, Mouillac, B, Müller, C E, Murphy, P, Nahon, J-L, Ngo, T, Norel, X, Nyimanu, D, O'Carroll, A-M, Offermanns, S, Panaro, M A, Parmentier, M, Pertwee, R G, Pin, J-P, Prossnitz, E R, Quinn, M, Ramachandran, R, Ray, M, Reinscheid, R K, Rondard, P, Rovati, G E, Ruzza, C, Sanger, G J, Schöneberg, T, Schulte, G, Schulz, S, Segaloff, D L, Serhan, C N, Stoddart, L A, Sugimoto, Y, Summers, R, Tan, V P, Thal, D, Thomas, W W, Timmermans, P B M W M, Tirupula, K, Tulipano, G, Unal, H, Unger, T, Valant, C, Vanderheyden, P, Vaudry, D, Vaudry, H, Vilardaga, J-P, Walker, C S, Wang, J M, Ward, D T, Wester, H-J, Willars, G B, Woodruff, T M, Yao, C & Ye, R D 2021, ' THE CONCISE GUIDE TO PHARMACOLOGY 2021/22 : G protein-coupled receptors ', British Journal of Pharmacology, vol. 178 Suppl 1, no. S1, pp. S27-S156 . https://doi.org/10.1111/bph.15538
British journal of pharmacology, 178(S1), S27-S156. Wiley-Blackwell
Alexander, S P, Christopoulos, A, Davenport, A P, Kelly, E, Mathie, A, Peters, J A, Veale, E L, Armstrong, J F, Faccenda, E, Harding, S D, Pawson, A J, Southan, C, Davies, J A, Abbracchio, M P, Alexander, W, Al-Hosaini, K, Bäck, M, Barnes, N M, Bathgate, R, Beaulieu, J-M, Bernstein, K E, Bettler, B, Birdsall, N J M, Blaho, V, Boulay, F, Bousquet, C, Bräuner-Osborne, H, Burnstock, G, Caló, G, Castaño, J P, Catt, K J, Ceruti, S, Chazot, P, Chiang, N, Chini, B, Chun, J, Cianciulli, A, Civelli, O, Clapp, L H, Couture, R, Csaba, Z, Dahlgren, C, Dent, G, Singh, K D, Douglas, S D, Dournaud, P, Eguchi, S, Escher, E, Filardo, E J, Fong, T, Fumagalli, M, Gainetdinov, R R, Gasparo, M D, Gerard, C, Gershengorn, M, Gobeil, F, Goodfriend, T L, Goudet, C, Gregory, K J, Gundlach, A L, Hamann, J, Hanson, J, Hauger, R L, Hay, D L, Heinemann, A, Hollenberg, M D, Holliday, N D, Horiuchi, M, Hoyer, D, Hunyady, L, Husain, A, IJzerman, A P, Inagami, T, Jacobson, K A, Jensen, R T, Jockers, R, Jonnalagadda, D, Karnik, S, Kaupmann, K, Kemp, J, Kennedy, C, Kihara, Y, Kitazawa, T, Kozielewicz, P, Kreienkamp, H-J, Kukkonen, J P, Langenhan, T, Leach, K, Lecca, D, Lee, J D, Leeman, S E, Leprince, J, Li, X X, Williams, T L, Lolait, S J, Lupp, A, Macrae, R, Maguire, J, Mazella, J, McArdle, C A, Melmed, S, Michel, M C, Miller, L J, Mitolo, V, Mouillac, B, Müller, C E, Murphy, P, Nahon, J-L, Ngo, T, Norel, X, Nyimanu, D, O'Carroll, A-M, Offermanns, S, Panaro, M A, Parmentier, M, Pertwee, R G, Pin, J-P, Prossnitz, E R, Quinn, M, Ramachandran, R, Ray, M, Reinscheid, R K, Rondard, P, Rovati, G E, Ruzza, C, Sanger, G J, Schöneberg, T, Schulte, G, Schulz, S, Segaloff, D L, Serhan, C N, Stoddart, L A, Sugimoto, Y, Summers, R, Tan, V P, Thal, D, Thomas, W W, Timmermans, P B M W M, Tirupula, K, Tulipano, G, Unal, H, Unger, T, Valant, C, Vanderheyden, P, Vaudry, D, Vaudry, H, Vilardaga, J-P, Walker, C S, Wang, J M, Ward, D T, Wester, H-J, Willars, G B, Woodruff, T M, Yao, C & Ye, R D 2021, ' THE CONCISE GUIDE TO PHARMACOLOGY 2021/22 : G protein-coupled receptors ', British Journal of Pharmacology, vol. 178, no. S1, pp. S27-S156 . https://doi.org/10.1111/bph.15538
Alexander, S P, Christopoulos, A, Davenport, A P, Kelly, E, Mathie, A, Peters, J A, Veale, E L, Armstrong, J F, Faccenda, E, Harding, S D, Pawson, A J, Southan, C, Davies, J A, Abbracchio, M P, Alexander, W, Al-Hosaini, K, Bäck, M, Barnes, N M, Bathgate, R, Beaulieu, J-M, Bernstein, K E, Bettler, B, Birdsall, N J M, Blaho, V, Boulay, F, Bousquet, C, Bräuner-Osborne, H, Burnstock, G, Caló, G, Castaño, J P, Catt, K J, Ceruti, S, Chazot, P, Chiang, N, Chini, B, Chun, J, Cianciulli, A, Civelli, O, Clapp, L H, Couture, R, Csaba, Z, Dahlgren, C, Dent, G, Singh, K D, Douglas, S D, Dournaud, P, Eguchi, S, Escher, E, Filardo, E J, Fong, T, Fumagalli, M, Gainetdinov, R R, Gasparo, M D, Gerard, C, Gershengorn, M, Gobeil, F, Goodfriend, T L, Goudet, C, Gregory, K J, Gundlach, A L, Hamann, J, Hanson, J, Hauger, R L, Hay, D L, Heinemann, A, Hollenberg, M D, Holliday, N D, Horiuchi, M, Hoyer, D, Hunyady, L, Husain, A, IJzerman, A P, Inagami, T, Jacobson, K A, Jensen, R T, Jockers, R, Jonnalagadda, D, Karnik, S, Kaupmann, K, Kemp, J, Kennedy, C, Kihara, Y, Kitazawa, T, Kozielewicz, P, Kreienkamp, H-J, Kukkonen, J P, Langenhan, T, Leach, K, Lecca, D, Lee, J D, Leeman, S E, Leprince, J, Li, X X, Williams, T L, Lolait, S J, Lupp, A, Macrae, R, Maguire, J, Mazella, J, McArdle, C A, Melmed, S, Michel, M C, Miller, L J, Mitolo, V, Mouillac, B, Müller, C E, Murphy, P, Nahon, J-L, Ngo, T, Norel, X, Nyimanu, D, O'Carroll, A-M, Offermanns, S, Panaro, M A, Parmentier, M, Pertwee, R G, Pin, J-P, Prossnitz, E R, Quinn, M, Ramachandran, R, Ray, M, Reinscheid, R K, Rondard, P, Rovati, G E, Ruzza, C, Sanger, G J, Schöneberg, T, Schulte, G, Schulz, S, Segaloff, D L, Serhan, C N, Stoddart, L A, Sugimoto, Y, Summers, R, Tan, V P, Thal, D, Thomas, W W, Timmermans, P B M W M, Tirupula, K, Tulipano, G, Unal, H, Unger, T, Valant, C, Vanderheyden, P, Vaudry, D, Vaudry, H, Vilardaga, J-P, Walker, C S, Wang, J M, Ward, D T, Wester, H-J, Willars, G B, Woodruff, T M, Yao, C & Ye, R D 2021, ' THE CONCISE GUIDE TO PHARMACOLOGY 2021/22 : G protein-coupled receptors ', British Journal of Pharmacology, vol. 178 Suppl 1, no. S1, pp. S27-S156 . https://doi.org/10.1111/bph.15538
British journal of pharmacology, 178(S1), S27-S156. Wiley-Blackwell
Alexander, S P, Christopoulos, A, Davenport, A P, Kelly, E, Mathie, A, Peters, J A, Veale, E L, Armstrong, J F, Faccenda, E, Harding, S D, Pawson, A J, Southan, C, Davies, J A, Abbracchio, M P, Alexander, W, Al-Hosaini, K, Bäck, M, Barnes, N M, Bathgate, R, Beaulieu, J-M, Bernstein, K E, Bettler, B, Birdsall, N J M, Blaho, V, Boulay, F, Bousquet, C, Bräuner-Osborne, H, Burnstock, G, Caló, G, Castaño, J P, Catt, K J, Ceruti, S, Chazot, P, Chiang, N, Chini, B, Chun, J, Cianciulli, A, Civelli, O, Clapp, L H, Couture, R, Csaba, Z, Dahlgren, C, Dent, G, Singh, K D, Douglas, S D, Dournaud, P, Eguchi, S, Escher, E, Filardo, E J, Fong, T, Fumagalli, M, Gainetdinov, R R, Gasparo, M D, Gerard, C, Gershengorn, M, Gobeil, F, Goodfriend, T L, Goudet, C, Gregory, K J, Gundlach, A L, Hamann, J, Hanson, J, Hauger, R L, Hay, D L, Heinemann, A, Hollenberg, M D, Holliday, N D, Horiuchi, M, Hoyer, D, Hunyady, L, Husain, A, IJzerman, A P, Inagami, T, Jacobson, K A, Jensen, R T, Jockers, R, Jonnalagadda, D, Karnik, S, Kaupmann, K, Kemp, J, Kennedy, C, Kihara, Y, Kitazawa, T, Kozielewicz, P, Kreienkamp, H-J, Kukkonen, J P, Langenhan, T, Leach, K, Lecca, D, Lee, J D, Leeman, S E, Leprince, J, Li, X X, Williams, T L, Lolait, S J, Lupp, A, Macrae, R, Maguire, J, Mazella, J, McArdle, C A, Melmed, S, Michel, M C, Miller, L J, Mitolo, V, Mouillac, B, Müller, C E, Murphy, P, Nahon, J-L, Ngo, T, Norel, X, Nyimanu, D, O'Carroll, A-M, Offermanns, S, Panaro, M A, Parmentier, M, Pertwee, R G, Pin, J-P, Prossnitz, E R, Quinn, M, Ramachandran, R, Ray, M, Reinscheid, R K, Rondard, P, Rovati, G E, Ruzza, C, Sanger, G J, Schöneberg, T, Schulte, G, Schulz, S, Segaloff, D L, Serhan, C N, Stoddart, L A, Sugimoto, Y, Summers, R, Tan, V P, Thal, D, Thomas, W W, Timmermans, P B M W M, Tirupula, K, Tulipano, G, Unal, H, Unger, T, Valant, C, Vanderheyden, P, Vaudry, D, Vaudry, H, Vilardaga, J-P, Walker, C S, Wang, J M, Ward, D T, Wester, H-J, Willars, G B, Woodruff, T M, Yao, C & Ye, R D 2021, ' THE CONCISE GUIDE TO PHARMACOLOGY 2021/22 : G protein-coupled receptors ', British Journal of Pharmacology, vol. 178, no. S1, pp. S27-S156 . https://doi.org/10.1111/bph.15538
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef5f3d1320e3d9fb87604fe0e7987c5
https://cris.maastrichtuniversity.nl/en/publications/e6053af4-7c66-44a3-97bc-f7b87d1745a9
https://cris.maastrichtuniversity.nl/en/publications/e6053af4-7c66-44a3-97bc-f7b87d1745a9
Autor:
J. Alberto Olivares-Reyes, Frank M. Dautzenberg, Monica Diaz-Coranguez, Judith Hernandez-Aranda, Richard L. Hauger, Alma M. Fuentes-Gonzalez, Kevin J. Catt, G. Karina Parra-Mercado
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Frontiers in Endocrinology
Frontiers in Endocrinology
In the present study, we determined the cellular regulators of ERK1/2 and Akt signaling pathways in response to human CRF1 receptor (CRF1R) activation in transfected COS-7 cells. We found that Pertussis Toxin (PTX) treatment or sequestering Gβγ red
Autor:
Kevin J. Catt, Kalyan C. Tirupula, Jacqueline R. Kemp, Hamiyet Unal, Walter G. Thomas, Marc de Gasparo, Patrick Vanderheyden, László Hunyady, Tadashi Inagami, Ahsan Husain, Satoru Eguchi, Thomas Unger, Wayne R. Alexander, Sadashiva S. Karnik, Theodore L. Goodfriend, Kenneth E. Bernstein, Emanuel Escher, Mastgugu Horiuchi, Khuraijam Dhanachandra Singh, Pieter B.M.W.M. Timmermans
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2019
The actions of angiotensin II (Ang II) are mediated by AT1 and AT2 receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Angiotensin receptors [61, 152]), which have around 30% sequence similarity. The decapeptide angiotensin I, the octa
Publikováno v:
Cellular and Molecular Biology of the Renin-Angiotensin System ISBN: 9781351070492
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5a816441873c088c1f7bbba26421fbc
https://doi.org/10.1201/9781351070492-13
https://doi.org/10.1201/9781351070492-13
Autor:
László Hunyady, Mária Szekeres, Kevin J. Catt, Eszter Soltész-Katona, András Balla, Gábor Turu, Zsuzsanna Tóth, György L. Nádasy
Publikováno v:
Journal of Biological Chemistry. 287:31540-31550
In the vascular system angiotensin II (Ang II) causes vasoconstriction via the activation of type 1 angiotensin receptors. Earlier reports have shown that in cellular expression systems diacylglycerol produced during type 1 angiotensin receptor signa
Publikováno v:
Molecular and Cellular Endocrinology. 353:29-36
In the past years, the relationship between the endocannabinoid system (ECS) and other hormonal and neuromodulatory systems has been intensively studied. G protein-coupled receptors (GPCRs) can stimulate endocannabinoid (eCB) production via activatio
Publikováno v:
Molecular and Cellular Endocrinology. 314:158-163
The pulsatile secretion of GnRH from normal and immortalized hypothalamic GnRH neurons is highly calcium-dependent and is stimulated by cAMP. It is also influenced by agonist activation of the endogenous GnRH receptor (GnRH-R), which couples to multi