Curvature sensing lipid dynamics in a mitochondrial inner membrane model

Autor: Vinaya Kumar Golla, Kevin J. Boyd, Eric R. May

Publikováno v: Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)

Abstract Membrane curvature is essential for many cellular structures and processes, and factors such as leaflet asymmetry, lipid composition, and proteins all play important roles. Cardiolipin is the signature lipid of mitochondrial membranes and is

Externí odkaz: https://doaj.org/article/4411d732a6384f96a6a980dd9e1bcd18

Stability of Norwalk virus capsid protein interfaces evaluated by in-silico nanoindentation

Autor: Kevin J Boyd, Prakhar eBansal, Jun eFeng, Eric R May

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 3 (2015)

Norwalk virus causes severe gastroenteritis for which there is currently no specific anti-viral therapy. A stage of the infection process is uncoating of the protein capsid to expose the viral genome and allow for viral replication. A mechanical char

Externí odkaz: https://doaj.org/article/17d045ca110f498584f576ddb51c2ad2

Understanding Conformational Dynamics of Complex Lipid Mixtures Relevant to Biology

Autor: Mikkel Christensen, Frauke Gräter, Talia Zeppelin, Ana-Nicoleta Bondar, Camilo Aponte-Santamaría, Kevin J. Boyd, Carmen Domene, Peter Pohl, Pedro A. Fernandes, Lucia Sessa, Birgit Schiøtt, Maria J. Ramos, Siewert J. Marrink, Durba Sengupta, Konstantina Karathanou, M. Joanne Lemieux, Peter J. Quinn, Ran Friedman, Csaba Daday, Mónica Pickholz, Stefano Piotto, Fabian Keller, Davit Hakobyan, Valeria Zoni, Syma Khalid, Floris J. van Eerden, Stefano Vanni, Eric R. May, Andreas Heuer, João Coimbra, Marlon Becker, Richard J. Naftalin, Antara Mazumdar, Elena Arutyunova, Simona Concilio

Publikováno v: Friedman, R, Khalid, S, Aponte-Santamaría, C, Arutyunova, E, Becker, M, Boyd, K J, Christensen, M H, Coimbra, J T S, Concilio, S, Daday, C, van Eerden, F J, Fernandes, P A, Gräter, F, Hakobyan, D, Heuer, A, Karathanou, K, Keller, F, Lemieux, M J, Marrink, S J, May, E R, Mazumdar, A, Naftalin, R, Pickholz, M, Piotto, S, Pohl, P, Quinn, P, Ramos, M J, Schiøtt, B, Sengupta, D, Sessa, L, Vanni, S, Zeppelin, T, Zoni, V, Bondar, A N & Domene, C 2018, ' Understanding Conformational Dynamics of Complex Lipid Mixtures Relevant to Biology ', Journal of Membrane Biology, vol. 251, no. 5-6, pp. 609-631 . https://doi.org/10.1007/s00232-018-0050-y
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The Journal of Membrane Biology

This is a perspective article entitled “Frontiers in computational biophysics: understanding conformational dynamics of complex lipid mixtures relevant to biology” which is following a CECAM meeting with the same name. Fil: Friedman, Ran. Linnæu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d5c9e68c7426479035d0f27af9de39
https://hdl.handle.net/11370/358e5f81-077d-43c5-9ee5-4121558e6b5b

Molecular dynamics study of membrane permeabilization by wild-type and mutant lytic peptides from the non-enveloped Flock House virus

Autor: Shivangi Nangia, Eric R. May, Kevin J. Boyd

Publikováno v: Biochim Biophys Acta Biomembr

Flock House virus (FHV) serves as a model system for understanding infection mechanisms utilized by non-enveloped viruses to transport across cellular membranes. During the infection cycle of FHV, a fundamental stage involves disruption of the endoso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cdd41b5332982ee1658d0b227903c73
https://pubmed.ncbi.nlm.nih.gov/31678020

BUMPy: A Model-Independent Tool for Constructing Lipid Bilayers of Varying Curvature and Composition

Autor: Eric R. May, Kevin J. Boyd

Publikováno v: Journal of chemical theory and computation. 14(12)

Molecular dynamics is a powerful tool to investigate atomistic and mesoscopic phenomena in lipid bilayer systems. These studies have progressed with the advent of increased computational power, and efforts are now increasingly being directed toward i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da41d4db302816c58f6cbf5298f74988
https://pubmed.ncbi.nlm.nih.gov/30431272