Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Kevin J Thompson"'
Autor:
Kevin J Thompson, James N Ingle, Xiaojia Tang, Nicholas Chia, Patricio R Jeraldo, Marina R Walther-Antonio, Karunya K Kandimalla, Stephen Johnson, Janet Z Yao, Sean C Harrington, Vera J Suman, Liewei Wang, Richard L Weinshilboum, Judy C Boughey, Jean-Pierre Kocher, Heidi Nelson, Matthew P Goetz, Krishna R Kalari
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188873 (2017)
The inflammatory tumoral-immune response alters the physiology of the tumor microenvironment, which may attenuate genomic instability. In addition to inducing inflammatory immune responses, several pathogenic bacteria produce genotoxins. However the
Externí odkaz:
https://doaj.org/article/53af000f849c4c2dad2a356dba3d40b8
Autor:
Krishna Rani Kalari, Kevin J Thompson, Asha eNair, Xiaojia eTang, Matthew eBockol, Navya eJhawar, Suresh K Swaminathan, Val J Lowe, Karunya K Kandimalla
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
Externí odkaz:
https://doaj.org/article/951cf760aa254fcdaaddc6a79edf5db9
Autor:
Nadine Norton, Zhifu Sun, Yan W Asmann, Daniel J Serie, Brian M Necela, Aditya Bhagwate, Jin Jen, Bruce W Eckloff, Krishna R Kalari, Kevin J Thompson, Jennifer M Carr, Jennifer M Kachergus, Xochiquetzal J Geiger, Edith A Perez, E Aubrey Thompson
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81925 (2013)
Advantages of RNA-Seq over array based platforms are quantitative gene expression and discovery of expressed single nucleotide variants (eSNVs) and fusion transcripts from a single platform, but the sensitivity for each of these characteristics is un
Externí odkaz:
https://doaj.org/article/08cde7971d5a43eaa606d79d877059cf
Autor:
Krishna R Kalari, Brian M Necela, Xiaojia Tang, Kevin J Thompson, Melissa Lau, Jeanette E Eckel-Passow, Jennifer M Kachergus, S Keith Anderson, Zhifu Sun, Saurabh Baheti, Jennifer M Carr, Tiffany R Baker, Poulami Barman, Derek C Radisky, Richard W Joseph, Sarah A McLaughlin, High-seng Chai, Stephan Camille, David Rossell, Yan W Asmann, E Aubrey Thompson, Edith A Perez
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79298 (2013)
Our goal in these analyses was to use genomic features from a test set of primary breast tumors to build an integrated transcriptome landscape model that makes relevant hypothetical predictions about the biological and/or clinical behavior of HER2-po
Externí odkaz:
https://doaj.org/article/b4f7343083b74f57913c4b514a195e31
Autor:
Xiaojia Tang, Kevin J. Thompson, Krishna R. Kalari, Jason P. Sinnwell, Vera J. Suman, Peter T. Vedell, Sarah A. McLaughlin, Donald W. Northfelt, Alvaro Moreno Aspitia, Richard J. Gray, Jodi M. Carter, Richard Weinshilboum, Liewei Wang, Judy C. Boughey, Matthew P. Goetz
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-18 (2023)
Abstract Background Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype. Patients with TNBC are primarily treated with neoadjuvant chemotherapy (NAC). The response to NAC is prognostic, with reductions in overall surviva
Externí odkaz:
https://doaj.org/article/3af3f74d177a4754a631cf8c8eef5d57
Autor:
Kirsten G. M. Aspros, Jodi M. Carter, Tanya L. Hoskin, Vera J. Suman, Malayannan Subramaniam, Michael J. Emch, Zhenqing Ye, Zhifu Sun, Jason P. Sinnwell, Kevin J. Thompson, Xiaojia Tang, Esther P. B. Rodman, Xiyin Wang, Adam W. Nelson, Igor Chernukhin, Feda H. Hamdan, Elizabeth S. Bruinsma, Jason S. Carroll, Martin E. Fernandez-Zapico, Steven A. Johnsen, Krishna R. Kalari, Haojie Huang, Roberto A. Leon-Ferre, Fergus J. Couch, James N. Ingle, Matthew P. Goetz, John R. Hawse
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-15 (2022)
Abstract Triple Negative Breast Cancer (TNBC) accounts for 15–20% of all breast cancer cases, yet is responsible for a disproportionately high percentage of breast cancer mortalities. Thus, there is an urgent need to identify novel biomarkers and t
Externí odkaz:
https://doaj.org/article/cb14a3f8cc2f47efa372c800d589e31a
Autor:
George B. Saffouri, Robin R. Shields-Cutler, Jun Chen, Yi Yang, Heather R. Lekatz, Vanessa L. Hale, Janice M. Cho, Eric J. Battaglioli, Yogesh Bhattarai, Kevin J. Thompson, Krishna K. Kalari, Gaurav Behera, Jonathan C. Berry, Stephanie A. Peters, Robin Patel, Audrey N. Schuetz, Jeremiah J. Faith, Michael Camilleri, Justin L. Sonnenburg, Gianrico Farrugia, Jonathan R. Swann, Madhusudan Grover, Dan Knights, Purna C. Kashyap
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Small intestinal bacterial overgrowth (SIBO) has been associated with functional gastrointestinal disorders. Here, the authors show that SIBO may be a result of dietary preferences, and patient symptoms correlate with changes in small intestinal micr
Externí odkaz:
https://doaj.org/article/32a844355ed94b92862ae083fcfb70df
Autor:
Jia Yu, Bo Qin, Ann M. Moyer, Jason P. Sinnwell, Kevin J. Thompson, John A. Copland, Laura A. Marlow, James L. Miller, Ping Yin, Bowen Gao, Katherine Minter-Dykhouse, Xiaojia Tang, Sarah A. McLaughlin, Alvaro Moreno-Aspitia, Anthony Schweitzer, Yan Lu, Jason Hubbard, Donald W. Northfelt, Richard J. Gray, Katie Hunt, Amy L. Conners, Vera J. Suman, Krishna R. Kalari, James N. Ingle, Zhenkun Lou, Daniel W. Visscher, Richard Weinshilboum, Judy C. Boughey, Matthew P. Goetz, Liewei Wang
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-2 (2021)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/522cd7669360436690f876e3a87eb7fe
Autor:
Jia Yu, Bo Qin, Ann M. Moyer, Jason P. Sinnwell, Kevin J. Thompson, John A. Copland, Laura A. Marlow, James L. Miller, Ping Yin, Bowen Gao, Katherine Minter-Dykhouse, Xiaojia Tang, Sarah A. McLaughlin, Alvaro Moreno-Aspitia, Anthony Schweitzer, Yan Lu, Jason Hubbard, Donald W. Northfelt, Richard J. Gray, Katie Hunt, Amy L. Conners, Vera J. Suman, Krishna R. Kalari, James N. Ingle, Zhenkun Lou, Daniel W. Visscher, Richard Weinshilboum, Judy C. Boughey, Matthew P. Goetz, Liewei Wang
Publikováno v:
Breast Cancer Research, Vol 19, Iss 1, Pp 1-13 (2017)
Abstract Background Patient-derived xenografts (PDXs) are increasingly used in cancer research as a tool to inform cancer biology and drug response. Most available breast cancer PDXs have been generated in the metastatic setting. However, in the sett
Externí odkaz:
https://doaj.org/article/ff08d7b126a94ac2ae38cf69dca307e2
Autor:
Ciara C O'Sullivan, Jun He, Jason Sinnwell, Vera J Suman, Krishna R Kalari, Peter T Vedell, Ann M Moyer, Xiaojia Tang, Kevin J Thompson, Abe Eyman Casey, Alvaro Moreno-Aspitia, Donald W Northfelt, Minetta C Liu, Tufia C Haddad, Saranya Chumsri, Brendan McMenomy, Prema Peethambaram, Kathryn J Ruddy, Karthik V Giridhar, Roberto A Leon-Ferre, Mattias Bergqvist, Adrian Nordmark, Richard M Weinshilboum, Liewei Wang, Matthew P Goetz
Publikováno v:
Cancer Research. 82:P5-13
Background: Cyclin dependent 4/6 kinase inhibitors (CDK4/6i) and endocrine therapy (ET) have improved progression-free survival (PFS) and overall survival in HR+ MBC, but progression of disease ultimately occurs. Apart from HR+ status, there are no c