Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Kevin J Kramer"'
Autor:
Kevin J. Kramer, Erin M. Wilfong, Kelsey Voss, Sierra M. Barone, Andrea R. Shiakolas, Nagarajan Raju, Caroline E. Roe, Naveenchandra Suryadevara, Lauren M. Walker, Steven C. Wall, Ariana Paulo, Samuel Schaefer, Debolanle Dahunsi, Camille S. Westlake, James E. Crowe, Robert H. Carnahan, Jeffrey C. Rathmell, Rachel H. Bonami, Ivelin S. Georgiev, Jonathan M. Irish
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Vaccination against COVID-19 has shown activation of different immune cell types. Here the authors characterise the immune response to the SARS-CoV-2 mRNA vaccine using longitudinal CyTOF single cell approaches to characterise antigen specific B and
Externí odkaz:
https://doaj.org/article/54f0d07dda6a4419baae2ec37e6174d0
Autor:
Kelsey A. Pilewski, Steven Wall, Simone I. Richardson, Nelia P. Manamela, Kaitlyn Clark, Tandile Hermanus, Elad Binshtein, Rohit Venkat, Giuseppe A. Sautto, Kevin J. Kramer, Andrea R. Shiakolas, Ian Setliff, Jordan Salas, Rutendo E. Mapengo, Naveen Suryadevara, John R. Brannon, Connor J. Beebout, Rob Parks, Nagarajan Raju, Nicole Frumento, Lauren M. Walker, Emilee Friedman Fechter, Juliana S. Qin, Amyn A. Murji, Katarzyna Janowska, Bhishem Thakur, Jared Lindenberger, Aaron J. May, Xiao Huang, Salam Sammour, Priyamvada Acharya, Robert H. Carnahan, Ted M. Ross, Barton F. Haynes, Maria Hadjifrangiskou, James E. Crowe, Jr., Justin R. Bailey, Spyros Kalams, Lynn Morris, Ivelin S. Georgiev
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112044- (2023)
Summary: Despite prolific efforts to characterize the antibody response to human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) mono-infections, the response to chronic co-infection with these two ever-evolving viruses is poorly un
Externí odkaz:
https://doaj.org/article/1510f5933b314ee292c1c7de93695a93
Autor:
Naveenchandra Suryadevara, Andrea R. Shiakolas, Laura A. VanBlargan, Elad Binshtein, Rita E. Chen, James Brett Case, Kevin J. Kramer, Erica C. Armstrong, Luke Myers, Andrew Trivette, Christopher Gainza, Rachel S. Nargi, Christopher N. Selverian, Edgar Davidson, Benjamin J. Doranz, Summer M. Diaz, Laura S. Handal, Robert H. Carnahan, Michael S. Diamond, Ivelin S. Georgiev, James E. Crowe Jr.
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 11 (2022)
The protective human antibody response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) focuses on the spike (S) protein, which decorates the virion surface and mediates cell binding and entry. Most SARS-CoV-2 protective antibodies tar
Externí odkaz:
https://doaj.org/article/9fba5e9f15e74bbdb3531fad2680cb32
Autor:
Kevin J. Kramer, Nicole V. Johnson, Andrea R. Shiakolas, Naveenchandra Suryadevara, Sivakumar Periasamy, Nagarajan Raju, Jazmean K. Williams, Daniel Wrapp, Seth J. Zost, Lauren M. Walker, Steven C. Wall, Clinton M. Holt, Ching-Lin Hsieh, Rachel E. Sutton, Ariana Paulo, Rachel S. Nargi, Edgar Davidson, Benjamin J. Doranz, James E. Crowe, Jr., Alexander Bukreyev, Robert H. Carnahan, Jason S. McLellan, Ivelin S. Georgiev
Publikováno v:
Cell Reports, Vol 37, Iss 1, Pp 109784- (2021)
Summary: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineages that are more transmissible and resistant to currently approved antibody therapies poses a considerable challenge to the clinical treatment of coronavirus
Externí odkaz:
https://doaj.org/article/f0d8cdf7656645d0b29756b1b1c69e65
Autor:
Andrea R. Shiakolas, Kevin J. Kramer, Daniel Wrapp, Simone I. Richardson, Alexandra Schäfer, Steven Wall, Nianshuang Wang, Katarzyna Janowska, Kelsey A. Pilewski, Rohit Venkat, Robert Parks, Nelia P. Manamela, Nagarajan Raju, Emilee Friedman Fechter, Clinton M. Holt, Naveenchandra Suryadevara, Rita E. Chen, David R. Martinez, Rachel S. Nargi, Rachel E. Sutton, Julie E. Ledgerwood, Barney S. Graham, Michael S. Diamond, Barton F. Haynes, Priyamvada Acharya, Robert H. Carnahan, James E. Crowe, Jr., Ralph S. Baric, Lynn Morris, Jason S. McLellan, Ivelin S. Georgiev
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 6, Pp 100313- (2021)
Summary: The continual emergence of novel coronaviruses (CoV), such as severe acute respiratory syndrome-(SARS)-CoV-2, highlights the critical need for broadly reactive therapeutics and vaccines against this family of viruses. From a recovered SARS-C
Externí odkaz:
https://doaj.org/article/855d316603ff4ff6bce75cfb57c2d1a1
Publikováno v:
Vaccines, Vol 9, Iss 9, p 964 (2021)
Vaccination remains one of the most successful medical interventions in history, significantly decreasing morbidity and mortality associated with, or even eradicating, numerous infectious diseases. Although traditional immunization strategies have re
Externí odkaz:
https://doaj.org/article/b07b6ace652f43ba910b07117de7a427
Autor:
Andrea R. Shiakolas, Kevin J. Kramer, Nicole V. Johnson, Steven C. Wall, Naveenchandra Suryadevara, Daniel Wrapp, Sivakumar Periasamy, Kelsey A. Pilewski, Nagarajan Raju, Rachel Nargi, Rachel E. Sutton, Lauren M. Walker, Ian Setliff, James E. Crowe, Alexander Bukreyev, Robert H. Carnahan, Jason S. McLellan, Ivelin S. Georgiev
Publikováno v:
Nature Biotechnology. 40:1270-1275
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15e58678fb1c94d593ffb8ae6ceea928
https://doi.org/10.1038/s41587-022-01232-2
https://doi.org/10.1038/s41587-022-01232-2
Autor:
Robert H. Carnahan, Sierra Barone, Rachel H. Bonami, Andrea R. Shiakolas, Jonathan M. Irish, Camille S. Westlake, Ariana Paulo, Ivelin S. Georgiev, Erin M Wilfong, James E. Crowe, Lauren M. Walker, Debolanle O. Dahunsi, Nagarajan Raju, Kevin J Kramer, Kelsey Voss, Jeffrey C. Rathmell, Samuel Schaefer, Naveenchandra Suryadevara, Caroline E. Roe, Steven C. Wall
Publikováno v:
bioRxiv
SUMMARYRNA-based vaccines against SARS-CoV-2 are critical to limiting COVID-19 severity and spread. Cellular mechanisms driving antigen-specific responses to these vaccines, however, remain uncertain. We used single-cell technologies to identify and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e62513d5ff94225c9381ce6ab80618
https://europepmc.org/articles/PMC8328055/
https://europepmc.org/articles/PMC8328055/
Autor:
Rachel E. Sutton, Alexander Bukreyev, James E. Crowe, Robert H. Carnahan, Nagarajan Raju, Jason S. McLellan, Kevin J Kramer, Rachel S. Nargi, Lauren M. Walker, Sivakumar Periasamy, Naveenchandra Suryadevara, Ivelin S. Georgiev, Ian Setliff, Andrea R. Shiakolas, Daniel Wrapp, Kelsey A. Pilewski, Nicole V. Johnson
Publikováno v:
bioRxiv : the preprint server for biology.
SARS-CoV-2 therapeutic antibody discovery efforts have met with notable success but have been associated with a generally inefficient process, requiring the production and characterization of exceptionally large numbers of candidates for the identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d9fb58649296e07dda27694c788b50
https://pubmed.ncbi.nlm.nih.gov/35241839
https://pubmed.ncbi.nlm.nih.gov/35241839
Autor:
Andrea R, Shiakolas, Kevin J, Kramer, Nicole V, Johnson, Steven C, Wall, Naveenchandra, Suryadevara, Daniel, Wrapp, Sivakumar, Periasamy, Kelsey A, Pilewski, Nagarajan, Raju, Rachel, Nargi, Rachel E, Sutton, Lauren M, Walker, Ian, Setliff, James E, Crowe, Alexander, Bukreyev, Robert H, Carnahan, Jason S, McLellan, Ivelin S, Georgiev
Publikováno v:
bioRxiv
Although several monoclonal antibodies (mAbs) targeting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been approved for coronavirus disease 2019 (COVID-19) therapy, development was generally inefficient, with lead generation often
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d86a443d1996e78e77db68ea32cb1190
https://pubmed.ncbi.nlm.nih.gov/34100018
https://pubmed.ncbi.nlm.nih.gov/34100018