Zobrazeno 1 - 10
of 320
pro vyhledávání: '"Kevin J Anderson"'
Autor:
Frederick S. Varn, Kevin C. Johnson, Jan Martinek, Jason T. Huse, MacLean P. Nasrallah, Pieter Wesseling, Lee A.D. Cooper, Tathiane M. Malta, Taylor E. Wade, Thais S. Sabedot, Daniel Brat, Peter V. Gould, Adelheid Wöehrer, Kenneth Aldape, Azzam Ismail, Santhosh K. Sivajothi, Floris P. Barthel, Hoon Kim, Emre Kocakavuk, Nazia Ahmed, Kieron White, Indrani Datta, Hyo-Eun Moon, Steven Pollock, Christine Goldfarb, Ga-Hyun Lee, Luciano Garofano, Kevin J. Anderson, Djamel Nehar-Belaid, Jill S. Barnholtz-Sloan, Spyridon Bakas, Annette T. Byrne, Fulvio D’Angelo, Hui K. Gan, Mustafa Khasraw, Simona Migliozzi, D. Ryan Ormond, Sun Ha Paek, Erwin G. Van Meir, Annemiek M.E. Walenkamp, Colin Watts, Tobias Weiss, Michael Weller, Karolina Palucka, Lucy F. Stead, Laila M. Poisson, Houtan Noushmehr, Antonio Iavarone, Roel G.W. Verhaak, Kristin D. Alfaro, Samirkumar B. Amin, David M. Ashley, Christoph Bock, Andrew Brodbelt, Ketan R. Bulsara, Ana Valeria Castro, Jennifer M. Connelly, Joseph F. Costello, John F. de Groot, Gaetano Finocchiaro, Pim J. French, Anna Golebiewska, Ann C. Hau, Chibo Hong, Craig Horbinski, Kasthuri S. Kannan, Mathilde CM. Kouwenhoven, Anna Lasorella, Peter S. LaViolette, Keith L. Ligon, Allison K. Lowman, Shwetal Mehta, Hrvoje Miletic, Annette M. Molinaro, Ho Keung Ng, Simone P. Niclou, Johanna M. Niers, Joanna J. Phillips, Raul Rabadan, Ganesh Rao, Guido Reifenberger, Nader Sanai, Susan C. Short, Peter Sillevis Smitt, Andrew E. Sloan, Marion Smits, James M. Snyder, Hiromichi Suzuki, Ghazaleh Tabatabai, Georgette Tanner, William H. Tomaszewski, Michael Wells, Bart A. Westerman, Helen Wheeler, Jichun Xie, W.K. Alfred Yung, Gelareh Zadeh, Junfei Zhao, Roel GW. Verhaak
Publikováno v:
Cell, 185(12), 2184-2199.e16. Cell Press
Cell
Cell, vol 185, iss 12
The GLASS Consortium 2022, ' Glioma progression is shaped by genetic evolution and microenvironment interactions ', Cell, vol. 185, no. 12, pp. 2184-2199.e16 . https://doi.org/10.1016/j.cell.2022.04.038
Cell, 185(12), 2184-2199.e16. CELL PRESS
Cell
Cell, vol 185, iss 12
The GLASS Consortium 2022, ' Glioma progression is shaped by genetic evolution and microenvironment interactions ', Cell, vol. 185, no. 12, pp. 2184-2199.e16 . https://doi.org/10.1016/j.cell.2022.04.038
Cell, 185(12), 2184-2199.e16. CELL PRESS
The factors driving therapy resistance in diffuse glioma remain poorly understood. To identify treatment-associated cellular and genetic changes, we analyzed RNA and/or DNA sequencing data from the temporally separated tumor pairs of 304 adult patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36aa8231290284197e37208bfab4dbba
https://research.vumc.nl/en/publications/312bbb0a-1328-4405-bfbe-cce4f07b8a67
https://research.vumc.nl/en/publications/312bbb0a-1328-4405-bfbe-cce4f07b8a67
Autor:
Philip C. De Witt Hamer, Petra J. W. Pouwels, W Pieter Vandertop, Frederik Barkhof, Otto S. Hoekstra, Kevin J. Anderson, Sunit Das, Annemieke J.M. Rozemuller, Niels Verburg, Pieter Wesseling, Ronald Boellaard, Michael D. Taylor, Jeroen A.M. Beliën, Jaap C. Reijneveld, Roel G.W. Verhaak, Maqsood Yaqub, Joseph F. Costello, Kevin C. Johnson, Adriaan A. Lammertsma, Floris P. Barthel, Thomas Koopman
Publikováno v:
Neuro-Oncology, 23(12), 2054-2065. Oxford University Press
Verburg, N, Barthel, F P, Anderson, K J, Johnson, K C, Koopman, T, Yaqub, M M, Hoekstra, O S, Lammertsma, A A, Barkhof, F, Pouwels, P J W, Reijneveld, J C, Rozemuller, A J M, Beliën, J A M, Boellaard, R, Taylor, M D, Das, S, Costello, J F, Vandertop, W P, Wesseling, P, de Witt Hamer, P C & Verhaak, R G W 2021, ' Spatial concordance of DNA methylation classification in diffuse glioma ', Neuro-Oncology, vol. 23, no. 12, pp. 2054-2065 . https://doi.org/10.1093/neuonc/noab134
Neuro-Oncology, vol 23, iss 12
Neuro-oncology, 23(12), 2054-2065. Oxford University Press
Neuro-Oncology
Verburg, N, Barthel, F P, Anderson, K J, Johnson, K C, Koopman, T, Yaqub, M M, Hoekstra, O S, Lammertsma, A A, Barkhof, F, Pouwels, P J W, Reijneveld, J C, Rozemuller, A J M, Beliën, J A M, Boellaard, R, Taylor, M D, Das, S, Costello, J F, Vandertop, W P, Wesseling, P, de Witt Hamer, P C & Verhaak, R G W 2021, ' Spatial concordance of DNA methylation classification in diffuse glioma ', Neuro-Oncology, vol. 23, no. 12, pp. 2054-2065 . https://doi.org/10.1093/neuonc/noab134
Neuro-Oncology, vol 23, iss 12
Neuro-oncology, 23(12), 2054-2065. Oxford University Press
Neuro-Oncology
Background Intratumoral heterogeneity is a hallmark of diffuse gliomas. DNA methylation profiling is an emerging approach in the clinical classification of brain tumors. The goal of this study is to investigate the effects of intratumoral heterogenei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::500075d31fc825394290fd5a81476763
https://research.vumc.nl/en/publications/d65cfd45-3b50-4b9f-91a1-55557b4b5eab
https://research.vumc.nl/en/publications/d65cfd45-3b50-4b9f-91a1-55557b4b5eab
Autor:
Rahul Maurya, Hoon Kim, Sunit Das, Amit D. Gujar, Philip C. De Witt Hamer, Elise T. Courtois, Chew Yee Ngan, Kevin J. Anderson, Floris P. Barthel, Niels Verburg, Kevin C. Johnson, Dacheng Zhao, Ketan R. Bulsara, Martine Seignon, Paul Robson, Frederick S. Varn, Eun Hee Yi, Nicholas Navin, Marcos R. Estecio, Diane Luo, Roel G.W. Verhaak, Michael Samuels, Ming Tang
Publikováno v:
Johnson, K C, Anderson, K J, Courtois, E T, Gujar, A D, Barthel, F P, Varn, F S, Luo, D, Seignon, M, Yi, E, Kim, H, Estecio, M R H, Zhao, D, Tang, M, Navin, N E, Maurya, R, Ngan, C Y, Verburg, N, de Witt Hamer, P C, Bulsara, K, Samuels, M L, Das, S, Robson, P & Verhaak, R G W 2021, ' Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response ', Nature Genetics, vol. 53, no. 10, pp. 1456-1468 . https://doi.org/10.1038/s41588-021-00926-8
Nature Genetics, 53(10), 1456-1468. Nature Publishing Group
Nature Genetics, 53(10), 1456-1468. Nature Publishing Group
Glioma intratumoral heterogeneity enables adaptation to challenging microenvironments and contributes to therapeutic resistance. We integrated 914 single-cell DNA methylomes, 55,284 single-cell transcriptomes and bulk multi-omic profiles across 11 ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad1ae7e79d3ae7c7008a19eba37ea4d
https://research.vumc.nl/en/publications/3ef3cb20-34eb-4d85-9b84-b617090e15d1
https://research.vumc.nl/en/publications/3ef3cb20-34eb-4d85-9b84-b617090e15d1
Autor:
Samirkumar B. Amin, Erik P. Sulman, Martijn P. Lolkema, Emre Kocakavuk, Roel G.W. Verhaak, Frederick S. Varn, Floris P. Barthel, Kevin J. Anderson, Kevin C. Johnson
Publikováno v:
Nature Genetics, 53(7), 1088-1096. Nature Publishing Group
Kocakavuk, E, Anderson, K J, Varn, F S, Johnson, K C, Amin, S B, Sulman, E P, Lolkema, M P, Barthel, F P & Verhaak, R G W 2021, ' Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients with cancer ', Nature Genetics, vol. 53, no. 7, pp. 1088-1096 . https://doi.org/10.1038/s41588-021-00874-3
Kocakavuk, E, Anderson, K J, Varn, F S, Johnson, K C, Amin, S B, Sulman, E P, Lolkema, M P, Barthel, F P & Verhaak, R G W 2021, ' Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients with cancer ', Nature Genetics, vol. 53, no. 7, pp. 1088-1096 . https://doi.org/10.1038/s41588-021-00874-3
Ionizing radiation causes DNA damage and is a mainstay for cancer treatment, but understanding of its genomic impact is limited. We analyzed mutational spectra following radiotherapy in 190 paired primary and recurrent gliomas from the Glioma Longitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee36eec5dba803a7d59ed73959e53a2
https://research.vumc.nl/en/publications/b15d8f1a-a9c1-47b4-be37-c144e31e4bbd
https://research.vumc.nl/en/publications/b15d8f1a-a9c1-47b4-be37-c144e31e4bbd
Autor:
Lucy F. Stead, Daniel J. Brat, Michael D. Jenkinson, Michael Schuster, Michael Weller, Hiromichi Suzuki, Raul Rabadan, Kristin Alfaro, Do-Hyun Nam, D. Ryan Ormond, Gaetano Finocchiaro, Anzhela D. Moskalik, Hoon Kim, Jason K. Sa, Mustafa Khasraw, Chew Yee Ngan, Andrew E. Sloan, Peter Gould, Mark R. Gilbert, Ganesh Rao, Michael N. C. Fletcher, Brian L. Shaw, Houtan Noushmehr, Ketan R. Bulsara, Naema Nayyar, Elizabeth B. Claus, Colin Watts, Samirkumar B. Amin, Pim J. French, Rameen Beroukhim, Azzam Ismail, Erwin G. Van Meir, Matthew R. Grimmer, Andrew R Brodbelt, Joseph F. Costello, W. K. Alfred Yung, Susan C Short, Meihong Li, Guido Reifenberger, Adelheid Woehrer, Aruna Chakrabarty, Hui K Gan, Keith L. Ligon, Roel G.W. Verhaak, Chul-Kee Park, Simone P. Niclou, Georgette Tanner, Frederick S. Varn, Arnab Chakravarti, Javad Noorbakhsh, Floris P. Barthel, Jason T. Huse, Christoph Bock, Annette M. Molinaro, Georg Widhalm, Alexander F. Bruns, Olajide Abiola, Tathiane M. Malta, Pieter Wesseling, Tali Mazor, Donát Alpár, Peter Lichter, Jill S. Barnholtz-Sloan, Priscilla K. Brastianos, Antonio Iavarone, Laila M. Poisson, Jennifer Connelly, Bernhard Radlwimmer, Gelareh Zadeh, David M. Ashley, Ho Keung Ng, Ghazaleh Tabatabai, Peter A. E. Sillevis Smitt, Mathilde C.M. Kouwenhoven, Elizabeth J. Cochran, Jeffrey H. Chuang, Pratiti Bandopadhayay, Kevin C. Johnson, Marion Smits, Allison Lowman, John de Groot, Kevin J. Anderson, Johanna M. Niers, Bart A. Westerman, Peter S. LaViolette, Emre Kocakavuk, Kenneth Aldape, Kerrie L. McDonald
Publikováno v:
Nature, vol 576, iss 7785
Nature, 576(7785), 112-120. Nature Publishing Group
Nature
Barthel, F P, Johnson, K C, Varn, F S, Moskalik, A D, Tanner, G, Kocakavuk, E, Anderson, K J, Abiola, O, Aldape, K, Alfaro, K D, Alpar, D, Amin, S B, Ashley, D M, Bandopadhayay, P, Barnholtz-Sloan, J S, Beroukhim, R, Bock, C, Brastianos, P K, Brat, D J, Brodbelt, A R, Bruns, A F, Bulsara, K R, Chakrabarty, A, Chakravarti, A, Chuang, J H, Claus, E B, Cochran, E J, Connelly, J, Costello, J F, Finocchiaro, G, Fletcher, M N, French, P J, Gan, H K, Gilbert, M R, Gould, P V, Grimmer, M R, Iavarone, A, Ismail, A, Jenkinson, M D, Khasraw, M, Kim, H, Kouwenhoven, M C M, LaViolette, P S, Li, M, Lichter, P, Ligon, K L, Lowman, A K, Malta, T M, Mazor, T, McDonald, K L, Molinaro, A M, Nam, D H, Nayyar, N, Ng, H K, Ngan, C Y, Niclou, S P, Niers, J M, Noushmehr, H, Noorbakhsh, J, Ormond, D R, Park, C K, Poisson, L M, Rabadan, R, Radlwimmer, B, Rao, G, Reifenberger, G, Sa, J K, Schuster, M, Shaw, B L, Short, S C, Smitt, P A S, Sloan, A E, Smits, M, Suzuki, H, Tabatabai, G, Van Meir, E G, Watts, C, Weller, M, Wesseling, P, Westerman, B A, Widhalm, G, Woehrer, A, Yung, W K A, Zadeh, G, Huse, J T, De Groot, J F, Stead, L F, Verhaak, R G W & The GLASS Consortium 2019, ' Longitudinal molecular trajectories of diffuse glioma in adults ', Nature, vol. 576, no. 7785, pp. 112-120 . https://doi.org/10.1038/s41586-019-1775-1, https://doi.org/10.1038/s41586-019-1775-1
Nature, 576(7785), 112-120. Nature Publishing Group
Nature
Barthel, F P, Johnson, K C, Varn, F S, Moskalik, A D, Tanner, G, Kocakavuk, E, Anderson, K J, Abiola, O, Aldape, K, Alfaro, K D, Alpar, D, Amin, S B, Ashley, D M, Bandopadhayay, P, Barnholtz-Sloan, J S, Beroukhim, R, Bock, C, Brastianos, P K, Brat, D J, Brodbelt, A R, Bruns, A F, Bulsara, K R, Chakrabarty, A, Chakravarti, A, Chuang, J H, Claus, E B, Cochran, E J, Connelly, J, Costello, J F, Finocchiaro, G, Fletcher, M N, French, P J, Gan, H K, Gilbert, M R, Gould, P V, Grimmer, M R, Iavarone, A, Ismail, A, Jenkinson, M D, Khasraw, M, Kim, H, Kouwenhoven, M C M, LaViolette, P S, Li, M, Lichter, P, Ligon, K L, Lowman, A K, Malta, T M, Mazor, T, McDonald, K L, Molinaro, A M, Nam, D H, Nayyar, N, Ng, H K, Ngan, C Y, Niclou, S P, Niers, J M, Noushmehr, H, Noorbakhsh, J, Ormond, D R, Park, C K, Poisson, L M, Rabadan, R, Radlwimmer, B, Rao, G, Reifenberger, G, Sa, J K, Schuster, M, Shaw, B L, Short, S C, Smitt, P A S, Sloan, A E, Smits, M, Suzuki, H, Tabatabai, G, Van Meir, E G, Watts, C, Weller, M, Wesseling, P, Westerman, B A, Widhalm, G, Woehrer, A, Yung, W K A, Zadeh, G, Huse, J T, De Groot, J F, Stead, L F, Verhaak, R G W & The GLASS Consortium 2019, ' Longitudinal molecular trajectories of diffuse glioma in adults ', Nature, vol. 576, no. 7785, pp. 112-120 . https://doi.org/10.1038/s41586-019-1775-1, https://doi.org/10.1038/s41586-019-1775-1
The evolutionary processes that drive universal therapeutic resistance in adult patients with diffuse glioma remain unclear1,2. Here we analysed temporally separated DNA-sequencing data and matched clinical annotation from 222 adult patients with gli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42aa714cc58ed5e72980caca94e04350
https://pure.eur.nl/en/publications/b9198630-2a42-471b-be97-3c7b0986e7d4
https://pure.eur.nl/en/publications/b9198630-2a42-471b-be97-3c7b0986e7d4
Autor:
Brian Herbert, Kevin J. Anderson
In the penultimate issue of the final prequel to Dune, Ix isn't the only planet under siege, as militaries clash, plans crumble, leaders fall, and tainted Spice wreaks havoc. It all comes to a head as Lady Jessica goes into labor with her child of ma
Autor:
Brian Herbert, Kevin J. Anderson
The second official, NYT Bestselling prequel to Dune is adapted for the first time by award-winning novelists Brian Herbert and Kevin J. Anderson and artist Michael Shelfer (Domino), unveiling a closer look at the rising conflict between beloved char
Autor:
Brian Herbert, Kevin J. Anderson
Spanning from Arrakis to Wallach IX, formative moments from major characters'past in the Dune universe come to light driven by the ruthless machinations of House Harkonnen! Chaos ensues across planets with tense rescue missions, impossible choices, m
Autor:
Brian Herbert, Kevin J. Anderson
Where the Emperor is concerned, the legality of a massacre is of little matter, as revolution brews, and Jessica prepares to deliver her child of fate, the discovery of tainted spice cannot go unpunished… Meanwhile, Shaddam has the perfect subject
Autor:
Brian Herbert, Kevin J. Anderson
Prophetic visions, the nuclear carnage of war, political tension, and violent skirmishes unfold as the final prequel to Dune approaches its later chapters. Meanwhile, a tainted supply of spice sows chaos in the midst of the ongoing spice war.