Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Kevin J, Sokoloski"'
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Alphaviruses are arthropod-borne, single-stranded positive-sense RNA viruses that are recognized as rapidly emerging pathogens. Despite being exquisitely sensitive to the effects of the innate immune response alphaviruses can readily replicate, disse
Externí odkaz:
https://doaj.org/article/c5628144a7024e42ac06a4887a642252
Autor:
Kevin J. Sokoloski, Rochelle H. Holm, Melissa Smith, Easton E. Ford, Eric C. Rouchka, Ted Smith
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-6 (2023)
Abstract Background Despite a clear appreciation of the impact of human pathogens on community health, efforts to understand pathogen dynamics within populations often follow a narrow-targeted approach and rely on the deployment of specific molecular
Externí odkaz:
https://doaj.org/article/3aee852831924692a0f4f2663eceeeec
Publikováno v:
Viruses, Vol 15, Iss 1, p 164 (2023)
Alphaviruses are arthropod-borne, single-stranded positive sense RNA viruses that rely on the engagement of host RNA-binding proteins to efficiently complete the viral lifecycle. Because of this reliance on host proteins, the identification of host/p
Externí odkaz:
https://doaj.org/article/537b3349f36844b1b092bb3df94daf0e
Autor:
Claire E. Westcott, Kevin J. Sokoloski, Eric C. Rouchka, Julia H. Chariker, Rochelle H. Holm, Ray A. Yeager, Joseph B. Moore, Erin M. Elliott, Daymond Talley, Aruni Bhatnagar, Ted Smith
Publikováno v:
Pathogens, Vol 11, Iss 11, p 1249 (2022)
Despite entering an endemic phase, SARS-CoV-2 remains a significant burden to public health across the global community. Wastewater sampling has consistently proven utility to understanding SARS-CoV-2 prevalence trends and genetic variation as it rep
Externí odkaz:
https://doaj.org/article/7158c1840c3e4b9e81e9db8e03524369
Publikováno v:
Viruses, Vol 14, Iss 7, p 1423 (2022)
Alphaviruses cause significant outbreaks of febrile illness and debilitating multi-joint arthritis for prolonged periods after initial infection. We have previously reported that several host hnRNP proteins bind to the Sindbis virus (SINV) RNAs, and
Externí odkaz:
https://doaj.org/article/c988e8c360ba420c843b96cc94e70551
Autor:
James W Harder, Jing Ma, Pascale Alard, Kevin J Sokoloski, Edith Mathiowitz, Stacia Furtado, Nejat K Egilmez, Michele M Kosiewicz
Publikováno v:
Journal of Leukocyte Biology. 113:41-57
Systemic lupus erythematosus development is influenced by both sex and the gut microbiota. Metabolite production is a major mechanism by which the gut microbiota influences the immune system, and we have previously found differences in the fecal meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5102cfbc1696245e7a2e9ae7c564685
https://doi.org/10.1093/jleuko/qiac002
https://doi.org/10.1093/jleuko/qiac002
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT Alphaviruses are positive-sense RNA viruses that utilize a 5′ cap structure to facilitate translation of viral proteins and to protect the viral RNA genome. Nonetheless, significant quantities of viral genomic RNAs that lack a canonical 5
Externí odkaz:
https://doaj.org/article/45cab0136a9e4a81873d836c22da1439
Autor:
Brian D Carey, Ivan Akhrymuk, Bibha Dahal, Chelsea L Pinkham, Nicole Bracci, Sarah Finstuen-Magro, Shih-Chao Lin, Caitlin W Lehman, Kevin J Sokoloski, Kylene Kehn-Hall
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008282 (2020)
Protein phosphorylation plays an important role during the life cycle of many viruses. Venezuelan equine encephalitis virus (VEEV) capsid protein has recently been shown to be phosphorylated at four residues. Here those studies are extended to determ
Externí odkaz:
https://doaj.org/article/49b2ae15c6664592adc90c5d81263f5e
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0238254 (2020)
The identification of host / pathogen interactions is essential to both understanding the molecular biology of infection and developing rational intervention strategies to overcome disease. Alphaviruses, such as Sindbis virus, Chikungunya virus, and
Externí odkaz:
https://doaj.org/article/7f4470a7507640759e82171549fa6155
Autor:
Eric C. Rouchka, Julia H. Chariker, Kumar Saurabh, Sabine Waigel, Wolfgang Zacharias, Mei Zhang, Daymond Talley, Ian Santisteban, Madeline Puccio, Sarah Moyer, Rochelle H. Holm, Ray A. Yeager, Kevin J. Sokoloski, Joshua Fuqua, Aruni Bhatnagar, Ted Smith
Publikováno v:
Pathogens, Vol 10, Iss 10, p 1271 (2021)
Throughout the course of the ongoing SARS-CoV-2 pandemic there has been a need for approaches that enable rapid monitoring of public health using an unbiased and minimally invasive means. A major way this has been accomplished is through the regular
Externí odkaz:
https://doaj.org/article/7ac2b79287d14dfba8616c129f30eaf8