Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Kevin J, Otto"'
Autor:
Kyle P. O’Sullivan, Brian J. Philip, Jonathan L. Baker, John D. Rolston, Mark E. Orazem, Kevin J. Otto, Christopher R. Butson
Publikováno v:
Data, Vol 9, Iss 6, p 78 (2024)
Invasive intracranial electrodes are used in both clinical and research applications for recording and stimulation of brain tissue, providing essential data in acute and chronic contexts. The impedance characteristics of the electrode–tissue interf
Externí odkaz:
https://doaj.org/article/9a15c5a2e0a8493b9f9399ed8b2f4ec4
Publikováno v:
Bioelectronic Medicine, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract Background The purpose of this study was to evaluate if kilohertz frequency alternating current (KHFAC) stimulation of peripheral nerve could serve as a treatment for lumbar radiculopathy. Prior work shows that KHFAC stimulation can treat sc
Externí odkaz:
https://doaj.org/article/d67a9e4c4999440eb44e591aaec264b6
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
During type 1 diabetes, an autoimmune attack destroys pancreatic β-cells leading to the inability to maintain glucose homeostasis. These β-cells are neuroresponsive endocrine cells which normally secrete insulin partially in response to input from
Externí odkaz:
https://doaj.org/article/12e9cda4da684472b59150ea21691572
Autor:
Aritra Kundu, Erin Patrick, Seth Currlin, Ryan Madler, Francisco Delgado, Ahmed Fahmy, Rik Verplancke, Marco Ballini, Dries Braeken, Maaike Op de Beeck, Nima Maghari, Kevin J. Otto, Rizwan Bashirullah
Publikováno v:
Micromachines, Vol 15, Iss 2, p 280 (2024)
Compound nerve action potentials (CNAPs) were used as a metric to assess the stimulation performance of a novel high-density, transverse, intrafascicular electrode in rat models. We show characteristic CNAPs recorded from distally implanted cuff elec
Externí odkaz:
https://doaj.org/article/a5829b4f33d84176bbad1ca13b41b767
Autor:
Morgan E. Urdaneta, Nicolas G. Kunigk, Jesus D. Peñaloza-Aponte, Seth Currlin, Ian G. Malone, Shelley I. Fried, Kevin J. Otto
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Intracortical recordings can be used to voluntarily control external devices via brain-machine interfaces (BMI). Multiple factors, including the foreign body response (FBR), limit the stability of these neural signals over time. Current clinically ap
Externí odkaz:
https://doaj.org/article/8f40b6fb2cc645498de18c85132f54e6
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Intracortical microstimulation (ICMS) has shown promise in restoring quality of life to patients suffering from paralysis, specifically when used in the primary somatosensory cortex (S1). However, these benefits can be hampered by long-term degradati
Externí odkaz:
https://doaj.org/article/b4ff058299d34f98960621f8ad26d805
Autor:
Morgan E. Urdaneta, Nicolas G. Kunigk, Seth Currlin, Francisco Delgado, Shelley I. Fried, Kevin J. Otto
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Intracortical microstimulation (ICMS) of the somatosensory cortex (S1) can restore sensory function in patients with paralysis. Studies assessing the stability of ICMS have reported heterogeneous responses across electrodes and over time, potentially
Externí odkaz:
https://doaj.org/article/31af9feaf9c64d2f8296123ead435e4d
Autor:
Michael D. Sunshine, Antonino M. Cassarà, Esra Neufeld, Nir Grossman, Thomas H. Mareci, Kevin J. Otto, Edward S. Boyden, David D. Fuller
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Sunshine et al use a combination of rat models and in silico modeling to show that temporal interference stimulation can prevent fatal apneas after opioid overdose, and can activate the diaphragm after spinal cord injury. This potentially paves the w
Externí odkaz:
https://doaj.org/article/2b94bcb188db43d4a437d393abdb0f27
Autor:
Vinata Vedam-Mai, Karl Deisseroth, James Giordano, Gabriel Lazaro-Munoz, Winston Chiong, Nanthia Suthana, Jean-Philippe Langevin, Jay Gill, Wayne Goodman, Nicole R. Provenza, Casey H. Halpern, Rajat S. Shivacharan, Tricia N. Cunningham, Sameer A. Sheth, Nader Pouratian, Katherine W. Scangos, Helen S. Mayberg, Andreas Horn, Kara A. Johnson, Christopher R. Butson, Ro'ee Gilron, Coralie de Hemptinne, Robert Wilt, Maria Yaroshinsky, Simon Little, Philip Starr, Greg Worrell, Prasad Shirvalkar, Edward Chang, Jens Volkmann, Muthuraman Muthuraman, Sergiu Groppa, Andrea A. Kühn, Luming Li, Matthew Johnson, Kevin J. Otto, Robert Raike, Steve Goetz, Chengyuan Wu, Peter Silburn, Binith Cheeran, Yagna J. Pathak, Mahsa Malekmohammadi, Aysegul Gunduz, Joshua K. Wong, Stephanie Cernera, Wei Hu, Aparna Wagle Shukla, Adolfo Ramirez-Zamora, Wissam Deeb, Addie Patterson, Kelly D. Foote, Michael S. Okun
Publikováno v:
Frontiers in Human Neuroscience, Vol 15 (2021)
Externí odkaz:
https://doaj.org/article/b1c3f1fa9cf84beaa3bfad4a1b3085c0
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Intracortical microelectrodes are neuroprosthetic devices used in brain-machine interfaces to both record and stimulate neural activity in the brain. These technologies have been improved by advances in microfabrication, which have led to the creatio
Externí odkaz:
https://doaj.org/article/98f5b4a4bf4645b7918c92c22db72795