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pro vyhledávání: '"Kevin H. Zhan"'
Autor:
Marcus D. Kelly, Matthew R. Pawlak, Kevin H. Zhan, Ghaidan A. Shamsan, Wendy R. Gordon, David J. Odde
Publikováno v:
APL Bioengineering, Vol 8, Iss 3, Pp 036102-036102-11 (2024)
Cell migration is the major driver of invasion and metastasis during cancer progression. For cells to migrate, they utilize the actin–myosin cytoskeleton and adhesion molecules, such as integrins and CD44, to generate traction forces in their envir
Externí odkaz:
https://doaj.org/article/1e07d54b25c34fafa4f2d643b0677027
Autor:
Syed Haider, Luned M. Badder, Lorena A. Ruiz, Mary Anne Durin, Catherine M. Green, Bramwell G. Lambrus, J. Ross Chapman, Thao P. Phan, Lauren T Evans, Zhong Y. Yeow, Andrew J. Holland, Phillip M. Scott, Elizabeth M. Park, Daniela Novo, Eleanor Knight, Christopher J. Lord, Daniela Moralli, Andrew Tutt, Rebecca Marlow, Kevin H. Zhan
Publikováno v:
Nature. 585:447-452
Genomic instability is a hallmark of cancer, and has a central role in the initiation and development of breast cancer1,2. The success of poly-ADP ribose polymerase inhibitors in the treatment of breast cancers that are deficient in homologous recomb
Autor:
Kevin M. Clutario, Phillip M. Scott, Elizabeth M. Park, Scott A. Gerber, Andrew J. Holland, Kevin H. Zhan, Katelyn B. Cassidy
Publikováno v:
The Journal of Cell Biology
Park et al. identify a role for a subset of mRNA splicing factors, including WBP11, in centriole biogenesis. WBP11 is required for the splicing of short, weak introns, including those found in TUBGCP6 pre-mRNA. Splicing of TUBGCP6, as well as other W