Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kevin H. Dykstra"'
Publikováno v:
Journal of Neurochemistry. 62:1734-1740
We applied in vivo microdialysis to assess the effects of dopaminergic and beta-adrenergic receptor stimulation on cyclic AMP efflux in rat striatum under chloral hydrate anesthesia. Dopamine (up to 1 mM) infused for 20 min through the probe did not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11ac3667396b4843736a224de8f6bd0
https://doi.org/10.1046/j.1471-4159.1994.62051734.x
https://doi.org/10.1046/j.1471-4159.1994.62051734.x
Publikováno v:
Clinical Trial Simulations ISBN: 9781441974143
The Clinical Utility IndexSM (CUISM) is a practical and useful approach for informing drug development decisions where multiple aspects of a drug’s clinical profile must be optimally balanced. In its most common application, a CUI is a model of pop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a79af0d008ce47dcceee36149a6aa8db
https://doi.org/10.1007/978-1-4419-7415-0_5
https://doi.org/10.1007/978-1-4419-7415-0_5
Autor:
Ivan N. Mefford, Melinda M. Scully, John K. Hsiao, Robert L. Dedrick, Paul F. Morrison, Peter M. Bungay, Kevin H. Dykstra
Publikováno v:
Journal of Neurochemistry. 58:931-940
Spatial solute concentration profiles resulting from in vivo microdialysis were measured in rat caudate-putamen by quantitative autoradiography. Radiolabeled sucrose was included in the dialysate, and the tissue concentration profile measured after i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::121375acbbcc24fab22c290abc2074cb
https://doi.org/10.1111/j.1471-4159.1992.tb09346.x
https://doi.org/10.1111/j.1471-4159.1992.tb09346.x
Autor:
Henry Y. Wang, Kevin H. Dykstra
Publikováno v:
Bioproducts and Bioprocesses 2 ISBN: 9783642493621
Most industrial bioprocesses are generally conducted in batch or fed batch modes with limited process control capabilities. The cell is essentially treated as a black box which takes up nutrients and produces the desired product. Improvements in prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d3e1fe529908e087f097dfe2192b3a2
https://doi.org/10.1007/978-3-642-49360-7_22
https://doi.org/10.1007/978-3-642-49360-7_22
Autor:
Henry Y. Wang, Kevin H. Dykstra
Publikováno v:
Biotechnology progress. 8(4)
Two-dimensional polyacrylamide gel electrophoresis (2D PAGE) is a method of separating complex protein mixtures, such as whole cell extracts, on the basis of protein isoelectric point and molecular weight. In bioprocess engineering, conventional 2D P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b1aece3c7e29b55f8d16edcf937d82
https://pubmed.ncbi.nlm.nih.gov/1368457
https://pubmed.ncbi.nlm.nih.gov/1368457
Autor:
Robert L. Dedrick, John K. Hsiao, Paul F. Morrison, Kevin H. Dykstra, Peter M. Bungay, Ivan N. Mefford
Publisher Summary This chapter discusses overall concepts of quantitative microdialysis, including some difficulties of application. The major factors that may influence the proper quantitative use of the microdialysis probe include: (1) microdialysa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b04e5efae4c968d711797c2db002f199
https://doi.org/10.1016/b978-0-444-81194-3.50008-3
https://doi.org/10.1016/b978-0-444-81194-3.50008-3
Autor:
Kevin H. Dykstra, Henry Y. Wang
Publikováno v:
Applied microbiology and biotechnology. 34(2)
Two-dimensional gel electrophoresis (2-D PAGE) was used to study the intracellular protein profile of Streptomyces griseus in relation to cycloheximide (CH) biosynthesis. Four proteins (CR1-CR4) were found to be significantly and specifically repress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af013ee2a0eba48d3ac595da18dbbf03
https://pubmed.ncbi.nlm.nih.gov/1367499
https://pubmed.ncbi.nlm.nih.gov/1367499
Publikováno v:
Biotechnology and Bioengineering. 32:356-362
The fermentation of Streptomyces griseus for the production of cycloheximide is similar to other antibiotic fermentations in that product synthesis is subject to feedback regulation and the desired product is degraded in the fermentation broth. The p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb5e6b71bf4dae47c5180cd7a180d3bb
https://doi.org/10.1002/bit.260320314
https://doi.org/10.1002/bit.260320314