Trauma ICU Prevalence Project: the diversity of surgical critical care

Autor: Anne Stey, Ram Nirula, Katherine Corey, Marie Crandall, Rachel C Dirks, Thomas Schroeppel, Jeffry Nahmias, Areg Grigorian, Adrian A Maung, Jeanette Podbielski, Matthew M Carrick, Lisa M Kodadek, Chang Liu, Christopher P Michetti, Samir M Fakhry, Karen Brasel, Niels D Martin, Erik J Teicher, Anna Newcomb, Amy Stewart, Grace Chang, Michael Foreman, Evan Elizabeth Rainey, Forrest O (Dell) Moore, Jessica Huang, Krista Kaups, Rachel L Sensenig, Janika L San Roman, Clay Cothren Burlew, Eric M Campion, Len Weireter, Katherine Kelley, Dennis Kim, Erin Howell, Charles Hu, Karen Lewandowski, Elizabeth D Dauer, Kaushik Mukherjee, Liz G Penaloza, Daniel C Cullinane, Vaidehi Agrawal, Manuel Lorenzo, Dana Ferrari-Light, Michael Coomaraswamy, Michaela A West, Joseph Farhat, Karen J Brasel, Jessica H Ballou, Byron C Drumheller, Jason Radowsky, David J Dries, Elizabeth Ramey, Nicole Goulet, David H Livingston, Jonathan P Meizoso, Tanya L Zakrison, Wendy L Wahl, Mary-Margaret Brandt, Fady S Nasrallah, Kathryn B Schaffer, Joseph V Sakran, Tatiana C P Cardenas, Meenakshi Rani, Abid Khan, Elisa Moskowitz, Todd W Costantini, Jay J Doucet, Claire Pederson, Kevin H Martin, Patrick L Bosarge, Paige Farley, Jennifer Mull, Philip A Efron, Ruth Davis, Henrik Berdel, Chris Culpepper, Sonlee D West, Ashley Keiler-Green, Lily Tung, Jason L Sperry, Vincent P Anto, Milos Buhavac, Linda Ann Dultz, Lillian Kao, Reanna Adams, Javier Romero, Graal Diaz, Grant V Bochicchio, Rohit K Rasane, Casey Hill, Andre Campbell

Publikováno v: Trauma Surgery & Acute Care Open, Vol 4, Iss 1 (2019)

Background Surgical critical care is crucial to the care of trauma and surgical patients. This study was designed to provide a contemporary assessment of patient types, injuries, and conditions in intensive care units (ICU) caring for trauma patients

Externí odkaz: https://doaj.org/article/a9db1d376ae0450c8273d84c23172af8

Disruption of c-di-GMP Signaling Networks Unlocks Cryptic Expression of Secondary Metabolites during Biofilm Growth in Burkholderia pseudomallei

Autor: Grace I. Borlee, Mihnea R. Mangalea, Kevin H. Martin, Brooke A. Plumley, Samuel J. Golon, Bradley R. Borlee

Publikováno v: Applied and Environmental Microbiology. 88

The regulation and production of secondary metabolites during biofilm growth of Burkholderia spp. is not well understood. To learn more about the crucial role and regulatory control of cryptic molecules produced during biofilm growth, we disrupted c-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12ec0ccc978e9b31501c1bd945dfe98
https://doi.org/10.1128/aem.02431-21

2-Aminoimidazoles Inhibit

Autor: Juan M, Belardinelli, Wei, Li, Kevin H, Martin, Michael J, Zeiler, Elena, Lian, Charlotte, Avanzi, Crystal J, Wiersma, Tuan Vu, Nguyen, Bhanupriya, Angala, Vinicius C N, de Moura, Victoria, Jones, Bradley R, Borlee, Christian, Melander, Mary, Jackson

Publikováno v: International journal of molecular sciences. 23(6)

Biofilm growth is thought to be a significant obstacle to the successful treatment of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7d7b6263b7c34de8d0cdd88f4107a635
https://pubmed.ncbi.nlm.nih.gov/35328372

Unique Features of Mycobacterium abscessus Biofilms Formed in Synthetic Cystic Fibrosis Medium

Autor: Juan M. Belardinelli, Wei Li, Charlotte Avanzi, Shiva K. Angala, Elena Lian, Crystal J. Wiersma, Zuzana Palčeková, Kevin H. Martin, Bhanupriya Angala, Vinicius C. N. de Moura, Callan Kerns, Victoria Jones, Mercedes Gonzalez-Juarrero, Rebecca M. Davidson, Jerry A. Nick, Bradley R. Borlee, Mary Jackson

Publikováno v: Frontiers in Microbiology 12:743126
Frontiers in Microbiology
Frontiers in Microbiology, Vol 12 (2021)

Characterizing Mycobacterium abscessus complex (MABSC) biofilms under host-relevant conditions is essential to the design of informed therapeutic strategies targeted to this persistent, drug-tolerant, population of extracellular bacilli. Using synthe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f615485618147b02541003e1734c6be
https://doi.org/10.3389/fmicb.2021.743126

Cyclic di-GMP-Responsive Transcriptional Reporter Bioassays in Pseudomonas aeruginosa

Autor: Bradley R, Borlee, Grace I, Borlee, Kevin H, Martin, Yasuhiko, Irie

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1657

3',5'-cyclic diguanosine monophosphate (cyclic di-GMP) is a bacterial secondary messenger molecule that regulates many important cellular activities and behaviors, such as motility and biofilm formation. While mass spectrometry protocols for quantita

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d655ce5d561e4db1600a69e7a8aa968e
https://pubmed.ncbi.nlm.nih.gov/28889289