Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kevin H, Goslen"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
A Krebs cycle intermediate metabolite, itaconate, has gained attention as a potential antimicrobial and autoimmune disease treatment due to its anti-inflammatory effects. While itaconate and its derivatives pose an attractive therapeutic option for t
Externí odkaz:
https://doaj.org/article/1791641852a64c1e8ad7bde9e41bc54b
Autor:
Giselle C. Meléndez, Kylie Kavanagh, Nazli Gharraee, Jessica L. Lacy, Kevin H. Goslen, Masha Block, Jordyn Whitfield, Alexander Widiapradja, Scott P. Levick
Publikováno v:
Biomedicine & Pharmacotherapy. 160:114365
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d0f6a0e4e950613ad04381b9886ed53
https://doi.org/10.1016/j.biopha.2023.114365
https://doi.org/10.1016/j.biopha.2023.114365
Publikováno v:
Frontiers in immunology. 13
A Krebs cycle intermediate metabolite, itaconate, has gained attention as a potential antimicrobial and autoimmune disease treatment due to its anti-inflammatory effects. While itaconate and its derivatives pose an attractive therapeutic option for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69955c8a13b1e912a76acca857eda7d9
https://pubmed.ncbi.nlm.nih.gov/35265064
https://pubmed.ncbi.nlm.nih.gov/35265064
Autor:
Monica C. Pillon, Mack Sobhany, Mario J. Borgnia, Juno M. Krahn, Allen L. Hsu, Jason Williams, Robin E. Stanley, Kevin H Goslen
Publikováno v:
Nature structural & molecular biology
Ribosome assembly is a complex process reliant on the coordination of trans-acting enzymes to produce functional ribosomal subunits and secure the translational capacity of cells. The endoribonuclease (RNase) Las1 and the poly-nucleotide kinase (PNK)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6693290b197680cc4a076bb56bf515f3
https://doi.org/10.1038/s41594-019-0289-8
https://doi.org/10.1038/s41594-019-0289-8
A Krebs cycle intermediate metabolite, itaconate, has gained attention as a potential antimicrobial and autoimmune disease treatment due to its anti-inflammatory effects. While itaconate and its derivatives pose an attractive therapeutic option for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bd0b24b0cbf7056cb20d5731a31872a
https://doi.org/10.1101/2021.02.01.429228
https://doi.org/10.1101/2021.02.01.429228
Autor:
Jacob Gordon, Melissa L. Wells, Jason Williams, Robin E. Stanley, Monica C. Pillon, Kevin H Goslen
Publikováno v:
J Biol Chem
The ribosome biogenesis factor Las1 is an essential endoribonuclease that is well-conserved across eukaryotes and a newly established member of the higher eukaryotes and prokaryotes nucleotide-binding (HEPN) domain-containing nuclease family. HEPN nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ab487ae32eb39d2dfb8edd961e7b72
https://europepmc.org/articles/PMC7196650/
https://europepmc.org/articles/PMC7196650/
Las1 is an essential endoribonuclease that is well-conserved across eukaryotes and a newly established member of the HEPN (higher eukaryotes and prokaryotes nucleotide-binding) nuclease family. HEPN nucleases participate in diverse RNA cleavage pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a28617f25692e5f39473edbd2d9927
https://doi.org/10.1101/760058
https://doi.org/10.1101/760058