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pro vyhledávání: '"Kevin Guertin"'
Akademický článek
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Autor:
Melanie Demers, Sarah Sturtevant, Kevin Guertin, Dipti Gupta, Kunal Desai, Benjamin Vieira, Alexandra Hicks, Ayman Ismail, Yukio Nakamura, Bronner Goncalves, Giuseppe Di Caprio, Ethan Schonbrun, Scott Hansen, Martin K. Safo, David K. Wood, John M. Higgins, David R. Light
Publikováno v:
Blood. 134:2260-2260
Dilution of HbS with non-sickling hemoglobin or hemoglobin with increased oxygen affinity is clinically beneficial in sickle cell disease. Aldehydes, including 5-HMF, tucaresol or GBT440, modify the N-terminus of HbS by reversible covalent imine form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d578b804ef5d5c112905dcc877ae17d
https://doi.org/10.1182/blood-2019-128727
https://doi.org/10.1182/blood-2019-128727
Autor:
Liaomin Peng, Daliya Banerjee, Jianhua Chao, Norm Allaire, Christine Loh, Patrick Cullen, Lan Wu, Jason D. Fontenot, Catherine Quigley, Robert Dunstan, Kevin Guertin, Stefan Hamann, Ayla Ergun, Linlin Zhao, Tao Wang, Arumugam Palanichamy
Publikováno v:
Immunology. 147(4)
Retinoic acid receptor‐related orphan nuclear receptor γ (ROR γ) orchestrates a pro‐inflammatory gene expression programme in multiple lymphocyte lineages including T helper type 17 (Th17) cells, γδ T cells, innate lymphoid cells and lymphoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de289028718a38510f0eb23fb01d057
https://pubmed.ncbi.nlm.nih.gov/26694902
https://pubmed.ncbi.nlm.nih.gov/26694902
Autor:
Kevin Guertin, Tonika Bohnert, Tao Wang, Howard Jones, Edward Yin-Shiang Lin, Daliya Banerjee, Tina Talreja, Istvan J. Enyedy, Kurt Van Vloten, Douglas Marcotte, Jianhua Chao, Jason D. Fontenot
Publikováno v:
Bioorganicmedicinal chemistry letters. 25(15)
The nuclear receptor RORγ plays a central role in controlling a pro-inflammatory gene expression program in several lymphocyte lineages including TH17 cells. RORγ-dependent inflammation has been implicated in the pathogenesis of several major autoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92cf92a880de37c49e8dc3ae5446756
https://pubmed.ncbi.nlm.nih.gov/26048789
https://pubmed.ncbi.nlm.nih.gov/26048789
Autor:
Joanne L. Viney, Victor Hong, Arthur G. Taveras, Chi-Chi Peng, Daliya Banerjee, Kevin Guertin, Laura Silvian, Richard H. Hutchings, Howard Jones, Douglas Marcotte, Liaomin Peng, Noel A. Powell, Kevin Little, Jianhua Chao, Tonika Bohnert, Kurt Van Vloten, Istvan J. Enyedy, Jason D. Fontenot
Publikováno v:
Bioorganicmedicinal chemistry letters. 25(15)
RORγt is a pivotal regulator of a pro-inflammatory gene expression program implicated in the pathology of several major human immune-mediated diseases. Evidence from mouse models demonstrates that genetic or pharmacological inhibition of RORγ activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12513df04b12ba87745ee6c80e88a93
https://pubmed.ncbi.nlm.nih.gov/26048806
https://pubmed.ncbi.nlm.nih.gov/26048806