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pro vyhledávání: '"Kevin Goosse"'
Publikováno v:
The American Journal of Clinical Nutrition. 94:S1824-S1829
Type 2 diabetes arises when the endocrine pancreas fails to secrete sufficient insulin to cope with metabolic demands resulting from β cell secretory dysfunction, decreased β cell mass, or both. Epidemiologic studies have shown strong relations bet
Publikováno v:
Journal of Endocrinology. 200:177-187
An increased vulnerability of adult β-cells seems to be programmed in early life as adult islets from the progeny of dams fed a low-protein diet exhibited an increased apoptotic rate after cytokine stimulation. This was prevented by maternal taurine
Autor:
Claude Remacle, Thomas Bouckenooghe, Brigitte Reusens, Giorgia Sisino, Kevin Goosse, Sandra Aurientis
Publikováno v:
Acta physiologica (Oxford, England). 210(1)
Background: Epidemiological studies related poor maternal nutrition and subsequent growth retardation in the progeny to the development of diabetes later in life. Low-protein diet during gestation altered the beta-cell development of the rat progeny
Autor:
Marie-Thérèse Ahn, A. Renard, Brigitte Reusens, Claude Remacle, Kevin Goosse, J. Tamarit-Rodriguez, L. Kalbe, S. Merezak
Publikováno v:
Diabetologia. 47(4)
A maternal low-protein diet has been shown to induce an increased susceptibility of fetal islets to cytokines, but this effect can be avoided by maternal taurine supplementation. Here, we question whether these effects persist until adulthood in the