Výsledky vyhledávání - "Kevin Gillinder"

Akademický článek

Mutations in linker-2 of KLF1 impair expression of membrane transporters and cytoskeletal proteins causing hemolysis

Autor: Stephen Huang, Casie Reed, Melissa Ilsley, Graham Magor, Michael Tallack, Michael Landsberg, Helen Mitchell, Kevin Gillinder, Andrew Perkins

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Abstract The SP/KLF family of transcription factors harbour three C-terminal C2H2 zinc fingers interspersed by two linkers which confers DNA-binding to a 9-10 bp motif. Mutations in KLF1, the founding member of the family, are common. Missense mutati

Externí odkaz: https://doaj.org/article/41a563bbd8e9432d9d4dc9755cd58dc0

Zobrazit plný text záznamu

Akademický článek

A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasia

Autor: Zewen K. Tuong, Samuel W. Lukowski, Quan H. Nguyen, Janin Chandra, Chenhao Zhou, Kevin Gillinder, Abate A. Bashaw, John R. Ferdinand, Benjamin J. Stewart, Siok Min Teoh, Sarah J. Hanson, Katharina Devitt, Menna R. Clatworthy, Joseph E. Powell, Ian H. Frazer

Publikováno v: iScience, Vol 24, Iss 11, Pp 103326- (2021)

Summary: Langerhans cells (LC) are skin-resident antigen-presenting cells that regulate immune responses to epithelial microorganisms. Human papillomavirus (HPV) infection can promote malignant epithelial transformation. As LCs are considered importa

Externí odkaz: https://doaj.org/article/08f0ec2087624af0b1807e9af63d460a

Zobrazit plný text záznamu