Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kevin Gahan"'
Autor:
Catherine Tighe, Monica de Gaetano, Andrea Zanetti, Catherine Godson, Jianmin Chen, Patrick J. Guiry, Mark E. Cooper, Xavier Leroy, Kevin Gahan, Eoin P. Brennan, Derek W. Gilroy, Antonino Cacace, Mauro Perretti, Mariam Marai, Justine Newson, Andrew Gaffney, Phillip Kantharidis
Publikováno v:
Journal of Medicinal Chemistry
Failure to resolve inflammation underlies many prevalent pathologies. Recent insights have identified lipid mediators, typified by lipoxins (LXs), as drivers of inflammation resolution, suggesting potential therapeutic benefit. We report the asymmetr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c0a8aae72d9162c7a12aafaa264eb1
https://doi.org/10.1021/acs.jmedchem.1c00403
https://doi.org/10.1021/acs.jmedchem.1c00403
Autor:
Patrick J. Guiry, Celso Martins Queiroz-Junior, Kevin Gahan, Monica de Gaetano, Vivian Louise Soares de Oliveira, Eoin P. Brennan, Izabela Galvão, Eliza Mathias Melo, Juliana P. Vago, Catherine Godson, Mauro M. Teixeira
Publikováno v:
Pharmacological Research. 165:105445
The resolution of inflammation is a dynamic process, characterized by the biosynthesis of pro-resolving mediators, including the lipid Lipoxin A4 (LXA4). LXA4 acts on the N-formyl peptide receptor 2 (FPR2/ALX) to mediate anti-inflammatory and pro-res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d8de8fac5be310ab54663f6ef94eb4
https://doi.org/10.1016/j.phrs.2021.105445
https://doi.org/10.1016/j.phrs.2021.105445
Autor:
Monica, de Gaetano, Eibhlín, Butler, Kevin, Gahan, Andrea, Zanetti, Mariam, Marai, Jianmin, Chen, Antonino, Cacace, Emily, Hams, Catherine, Maingot, Alisha, McLoughlin, Eoin, Brennan, Xavier, Leroy, Christine E, Loscher, Padraic, Fallon, Mauro, Perretti, Catherine, Godson, Patrick J, Guiry
Publikováno v:
European journal of medicinal chemistry. 162
Lipoxins (LXs) are endogenously generated eicosanoids with potent bio-actions consistent with attenuation of inflammation. The costly synthesis and metabolic instability of LXs may limit their therapeutic potential. Here we report the synthesis and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9675aee14297a6c70baa45c58a2e40d6
https://pubmed.ncbi.nlm.nih.gov/30419493
https://pubmed.ncbi.nlm.nih.gov/30419493
Autor:
Emily Hams, Eoin P. Brennan, Jianmin Chen, Christine E. Loscher, Catherine Maingot, Xavier Leroy, Catherine Godson, Monica de Gaetano, Antonino Cacace, Patrick J. Guiry, Eibhlín Butler, Padraic G. Fallon, Andrea Zanetti, Mariam Marai, Alisha McLoughlin, Mauro Perretti, Kevin Gahan
Publikováno v:
European Journal of Medicinal Chemistry
Lipoxins (LXs) are endogenously generated eicosanoids with potent bio-actions consistent with attenuation of inflammation. The costly synthesis and metabolic instability of LXs may limit their therapeutic potential. Here we report the synthesis and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09894d06fc9e91c7faab5e30622cfe4d