Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kevin G. Soucy"'
Autor:
Kevin G. Soucy, Guruprasad A. Giridharan, Carlo R. Bartoli, Dustin Phillips, Michael A. Sobieski, Robert D. Dowling, Zhongjun J. Wu, William B. Wead, Steven C. Koenig, Mark S. Slaughter, Sumanth D. Prabhu
Publikováno v:
Annals of Biomedical Engineering. 45:1475-1486
Continuous-flow left ventricular assist devices (CF LVADs) are rotary blood pumps that improve mean blood flow, but with potential limitations of non-physiological ventricular volume unloading and diminished vascular pulsatility. In this study, we te
Autor:
Jorge H. Jimenez, Kevin G. Soucy, Michael A. Sobieski, Mark S. Slaughter, Guruprasad A. Giridharan, Gretel Monreal, Seth West, Steven C. Koenig, Young Choi
Publikováno v:
ASAIO Journal. 60:617-625
APK Advanced Medical Technologies (Atlanta, GA) is developing a sutureless beating heart (SBH) left ventricular assist device (LVAD) connector system consisting of anchoring titanium coil, titanium cannula with integrated silicone hemostatic valve, c
Autor:
Guruprasad A. Giridharan, Leslie C. Sherwood, Gretel Monreal, Kevin G. Soucy, Steven C. Koenig, Mark S. Slaughter, Charles R. Shambaugh, Katherine Chorpenning, Daniel Tamez, Jeffrey A. LaRose, Michael A. Sobieski
Publikováno v:
ASAIO Journal. 60:170-177
Implantation of ventricular assist devices (VADs) for the treatment of end-stage heart failure (HF) falls decidedly short of clinical demand, which exceeds 100,000 HF patients per year. Ventricular assist device implantation often requires major surg
Autor:
Guruprasad A. Giridharan, Steven C. Koenig, Kevin G. Soucy, Michael A. Sobieski, Mark S. Slaughter
Publikováno v:
ASAIO Journal. 59:410-419
Clinical acceptance of ventricular assist devices (VADs) as long-term heart failure therapy requires safe and effective circulatory support for a minimum of 5 years. Yet, VAD failure beyond 2 years of support is still a concern. Currently, device con
Autor:
Mark S. Slaughter, Kevin G. Soucy, Steven C. Koenig, Michael A. Sobieski, Guruprasad A. Giridharan
Publikováno v:
ASAIO Journal. 59:355-366
Ventricular assist devices (VADs) have been successfully used as a bridge to heart transplant and destination therapy (DT) for congestive heart failure (HF) patients. Recently, continuous flow VAD (CVAD) has emerged as an attractive clinical option f
Autor:
Carrie J. Benzinger, Kevin G. Soucy, M. Keith Sharp, Steven C. Koenig, Mark S. Slaughter, Guruprasad A. Giridharan, Michael A. Sobieski, Joel D. Graham
Publikováno v:
Cardiovascular Engineering and Technology. 4:161-170
A growing number of elderly patients with significant co-morbidities do not meet the inclusion criteria for conventional cardiac surgical therapies, including aortic valve replacement and mechanical circulatory support. To meet this clinical need, an
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 153(1)
Autor:
Marcelo E. Vazquez, Hyun Kyo Lim, Jae Hyung Kim, Dan E. Berkowitz, Kevin G. Soucy, Baris Sevinc, Maggie Kuo, Young S. Oh, Artin A. Shoukas, David O. Attarzadeh
Publikováno v:
Radiation Research. 176:474-485
Ionizing radiation has been implicated in the development of significant cardiovascular complications. Since radiation exposure is associated with space exploration, astronauts are potentially at increased risk of accelerated cardiovascular disease.
Autor:
Patricia A. Soucy, Raghav Ramachandran, David O. Attarzadeh, Kevin G. Soucy, Lewis H. Romer, Dan E. Berkowitz, Artin A. Shoukas
Publikováno v:
Radiation and Environmental Biophysics. 49:397-404
Radiation exposure can increase the risk for many non-malignant physiological complications, including cardiovascular disease. We have previously demonstrated that ionizing radiation can induce endothelial dysfunction, which contributes to increased
Autor:
Andre Camara, Hunter C. Champion, Gautam Sikka, Artin A. Shoukas, Monica Ilies, David W. Christianson, Sungwoo Ryoo, Kevin G. Soucy, Trinity J. Bivalacqua, Dan E. Berkowitz, Daniel Nyhan, Jae Hyung Kim, Young Jun Oh, Lakshmi Santhanam, Lukasz J. Bugaj, Alanah Webb
Publikováno v:
Journal of Applied Physiology. 107:1249-1257
There is increasing evidence that upregulation of arginase contributes to impaired endothelial function in aging. In this study, we demonstrate that arginase upregulation leads to endothelial nitric oxide synthase (eNOS) uncoupling and that in vivo c