Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kevin G. Reuter"'
Autor:
Andre Hermans, Piero M. Armenante, Gerard Bredael, Kevin G. Reuter, Sanjaykumar Patel, Chadakarn Sirasitthichoke
Publikováno v:
International Journal of Pharmaceutics. 607:120976
The USP Apparatus 1 (rotating basket), typically used to assess drug product reproducibility and evaluate oral solid dosage forms performance, consists of a cylindrical glass vessel with a hemispherical bottom and a wire basket rotating at constant s
Autor:
Pramod Kotwal, Filippos Kesisoglou, Andreas Abend, Kevin G. Reuter, Celeste Frankenfeld, Leah Xiong, Xiaohua Zhang
Publikováno v:
The AAPS journal. 22(1)
Dissolution experiments to support an active pharmaceutical ingredient (API) form change in Verubecestat immediate release tablets were performed following current regulatory guidance published by health authorities in Canada, Australia, Japan, the E
Autor:
Rihe Liu, Joseph M. DeSimone, J. Christopher Luft, Dong Wook Kim, Kevin G. Reuter, Jillian L. Perry
Publikováno v:
Nano Letters. 15:6371-6378
In this Letter, we varied targeting ligand density of an EGFR binding affibody on the surface of two different hydrogel PRINT nanoparticles (80 nm × 320 and 55 nm × 60 nm) and monitored effects on target-cell association, off-target phagocytic upta
Autor:
Siddhi Dudhat, Michael Heslinga, Kevin G. Reuter, Irina Kazakevich, Vivek Shah, William P. Forrest, Yun Mao, Claudia Neri, Sanjaykumar Patel
Publikováno v:
AAPS PharmSciTech. 19(1)
Long-acting or extended release parenteral dosage forms have attracted extensive attention due to their ability to maintain therapeutic drug concentrations over long periods of time and reduce administration frequency, thus improving patient complian
Autor:
Jillian L. Perry, Chad V. Pecot, William C. Zamboni, Kevin G. Reuter, J. Christopher Luft, Joseph M. DeSimone
As the enhanced permeation and retention (EPR) effect continues to be a controversial topic in nanomedicine, we sought to examine EPR as a function of nanoparticle size, tumor model, and tumor location, while also evaluating tumors for EPR mediating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e151d159ed0a88caf5a496b3fdc30e5
Autor:
J. Chris Luft, James E. Bear, Marc P. Kai, Kevin P. Herlihy, Kevin G. Reuter, Joseph M. DeSimone, Jillian L. Perry, Mary E. Napier, Stephen W. Jones
Publikováno v:
Nano Letters. 12:5304-5310
In this account, we varied PEGylation density on the surface of hydrogel PRINT nanoparticles and systematically observed the effects on protein adsorption, macrophage uptake, and circulation time. Interestingly, the density of PEGylation necessary to
Autor:
Jillian L, Perry, Marc P, Kai, Kevin G, Reuter, Charles, Bowerman, J, Christopher Luft, Joseph M, DeSimone
Publikováno v:
Cancer treatment and research. 166
Nanoparticle properties such as size, shape, deformability, and surface chemistry all play a role in nanomedicine drug delivery in cancer. While many studies address the behavior of particle systems in a biological setting, revealing how these proper
Autor:
Kevin G. Reuter, Charles J. Bowerman, Marc P. Kai, J. Chris Luft, Jillian L. Perry, Joseph M. DeSimone
Publikováno v:
Cancer Treatment and Research ISBN: 9783319165547
Nanoparticle properties such as size, shape, deformability, and surface chemistry all play a role in nanomedicine drug delivery in cancer. While many studies address the behavior of particle systems in a biological setting, revealing how these proper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8b73e43ffabcc3ca463222e7a833eca
https://doi.org/10.1007/978-3-319-16555-4_12
https://doi.org/10.1007/978-3-319-16555-4_12
Autor:
Joseph M. DeSimone, Lishan Su, Karen P. McKinnon, Gregory D. Sempowski, Tammy W. Shen, Reid A. Roberts, Haitao Guo, Kevin G. Reuter, Gregory R. Robbins, Jenny P.-Y. Ting
Ideal nanoparticle (NP)-based drug and vaccine delivery vectors should be free of inherent cytotoxic or immunostimulatory properties. Therefore, determining baseline immune responses to nanomaterials is of utmost importance when designing human thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce65118ff458384ac692b20af051170d
Autor:
Kevin G. Reuter, JillianL. Perry, Dongwook Kim, J. Christopher Luft, Rihe Liu, Joseph M. DeSimone
Publikováno v:
Nano Letters; Oct2015, Vol. 15 Issue 10, p6371-6378, 8p